• L-tyrosine → 4-coumarate + ammonium (R3408)
  • Overexpression
    • Plasmid
      • Escherichia coli HA-7
      • Escherichia coli HA-3
      • Escherichia coli HA-4
• D-erythrose 4-phosphate + phosphoenolpyruvate + H₂O ↔ 3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate (R576)
  • Overexpression
    • Plasmid
      • Escherichia coli HA-7
      • Escherichia coli HA-4
• prephenate + NAD⁺ → NADH + 3-(4-hydroxyphenyl)pyruvate + CO₂ (R727)
  • Overexpression
    • Plasmid
      • Escherichia coli HA-7
      • Escherichia coli HA-4
• chorismate ↔ prephenate (R69)
  • Overexpression
    • Plasmid
      • Escherichia coli HA-7
      • Escherichia coli HA-4
• coenzyme A + 4-coumarate + ATP → (E)-4-coumaroyl-CoA + diphosphate + AMP (R2776)
  • Overexpression
    • Plasmid
      • Escherichia coli HA-7
      • Escherichia coli HA-3
      • Escherichia coli HA-4
• (E)-4-coumaroyl-CoA + anthranilate → coenzyme A + avenanthramide D (R00898)
  • Overexpression
    • Plasmid
      • Escherichia coli HA-7
      • Escherichia coli HA-3
      • Escherichia coli HA-4
• L-glutamine + chorismate ↔ anthranilate + pyruvate + H⁺ + L-glutamate (R10)
  • Overexpression
    • Plasmid
      • Escherichia coli HA-7
      • Escherichia coli HA-3
      • Escherichia coli HA-4
• N-(5-phosphoribosyl)-anthranilate + diphosphate ↔ anthranilate + 5-phospho-α-D-ribose 1-diphosphate (R423)
  • Silencing
    • Genome
      • Escherichia coli HA-7