acetyl-CoA + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA ← coenzyme A + (6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA
β-L-rhamnosyl-(1,6)-β-D-glucosyl-(1,6)-α-D-glucosyl-(1,2)-β-D-glucuronate-(1,2)-α-D-mannosyl-(1,3)-β-D-glucosyl-(1,4)-α-D-glucosyl-diphosphoundecaprenol + acetyl-CoA → coenzyme A + β-L-rhamnosyl-(1,6)-β-D-glucosyl-(1,6)-α-D-glucosyl-(1,2)-β-D-glucuronate-(1,2)-6-O-acetyl-α-D-mannosyl-(1,3)-β-D-glucosyl-(1,4)-α-D-glucosyl-diphosphoundecaprenol
β-L-rhamnosyl-(1,6)-β-D-glucosyl-(1,6)-α-D-glucosyl-(1,2)-β-D-glucuronate-(1,2)-6-O-acetyl-α-D-mannosyl-(1,3)-β-D-glucosyl-(1,4)-α-D-glucosyl-diphosphoundecaprenol + acetyl-CoA → coenzyme A + β-L-rhamnosyl-(1,6)-β-D-glucosyl-(1,6)-α-D-glucosyl-(1,2)-β-D-glucuronate-(1,2)-6-O-acetyl-α-D-mannosyl-(1,3)-β-D-glucosyl-(1,4)-6-O-acetyl-α-D-glucosyl-diphosphoundecaprenol
2 hexadeca-4,7,10,13-tetraene-1-oyl-CoA + H2O → 2 coenzyme A + (6Z,9Z,12Z,15Z)-3-oxo-2-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]octadeca-6,9,12,15-tetraenoate + H+
H2O + (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA → coenzyme A + (7Z,10Z,13Z,16Z,19Z)-docosa-7,10,13,16,19-pentenoate + H+
malonyl-CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H+ → (8Z,11Z,14Z,17Z,20Z,23Z)-3-oxohexacosahexaenoyl-CoA + CO2 + coenzyme A
H2O + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA ↔ coenzyme A + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H+