Compound as reactive (14)

H⁺ + CO₂ → formate

H⁺ + L-glutamate → 4-aminobutanoate + CO₂

3-carboxy-8-(methylsulfanyl)-2-oxooctanoate + H⁺ → 8-(methylsulfanyl)-2-oxooctanoate + CO₂

2 NADPH + 2 H⁺ + 2 oxygen + L-tryptophan → 2 NADP⁺ + 3 H₂O + (E)-(indol-3-yl)acetaldehyde oxime + CO₂

prephenate + NADP⁺ → NADPH + 3-(4-hydroxyphenyl)pyruvate + CO₂

2-oxoglutarate + oxygen + gibberellin A₁₄ → succinate + gibberellin A₃₇ + CO₂

2 NADPH + 3 H⁺ + malonyl-CoA + stearidonoyl-CoA → 2 NADP⁺ + coenzyme A + H₂O + (8Z,11Z,14Z,17Z)-icosatetraenoyl-CoA + CO₂

N,N-dihydroxy-L-isoleucine + H⁺ → H₂O + (1E,2S)-2-methylbutanal oxime + CO₂

2-amino-5-chlorophenyl carbonate + H⁺ → 2-amino-5-chlorophenol + CO₂

2-oxoglutarate + H⁺ + oxygen + (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate → 2 CO₂ + H₂O + succinate + 3-[(E)-2-isocyanoethenyl]-1H-indole

2-oxoglutarate + oxygen + gibberellin A₅ → succinate + gibberellin A₆ + CO₂

C37-phenolcarboxyphthiodiolenone + H⁺ → C36-phenolphthiodiolenone A + CO₂

salicylate + H⁺ → phenol + CO₂

H⁺ + 3-nonaprenyl-4-hydroxybenzoate → 2-nonaprenylphenol + CO₂

L-ornithine + H⁺ → putrescine + CO₂

2-(4-hydroxyphenyl)-2-oxoacetate + H⁺ → 4-hydroxybenzaldehyde + CO₂

2 H⁺ + 3,6-dihydronicotinate → 1,2-dihydropyrimidine + CO₂

L-arginine + oxygen → H₂O + 4-guanidinobutyramide + CO₂

2-oxoglutarate + N¹-methyladenine + oxygen → formaldehyde + succinate + CO₂ + adenine

H⁺ + malonyl-CoA + ricinoleoyl-CoA → coenzyme A + 3-oxo-lesqueroloyl-CoA + CO₂

pimeloyl-CoA + H⁺ + L-alanine → coenzyme A + 8-amino-7-oxononanoate + CO₂

2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + H⁺ → 2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + CO₂

L-dopa + H⁺ → dopamine + CO₂

H⁺ + 4-hydroxybenzoate → phenol + CO₂

a reduced electron donor + H⁺ + oxygen + 15-demethoxy-aclacinomycin A → an oxidized electron donor + H₂O + 10-decarboxymethyl, 10-hydroxyaclacinomycin A + CO₂

malonyl-MmyA + acetyl-CoA → coenzyme A + acetoacetyl-MmyA + CO₂

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde + H⁺ → (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + CO₂

2 NADPH + 2 S-adenosyl-L-methionine + 2 oxygen + 4-methylsalicylate + H⁺ + all-trans-hexaprenyl diphosphate → 2 H₂O + 2 S-adenosyl-L-homocysteine + 2 NADP⁺ + 3-demethylubiquinol-6 + diphosphate + CO₂

6 glycolate + H⁺ → 2 succinate + 2 CO₂ + 4 H₂O + acetate

H⁺ + 3-octaprenyl-4-hydroxybenzoate → 2-octaprenylphenol + CO₂

4-(methylsulfanyl)-2-oxobutanoate + H⁺ → 3-(methylsulfanyl)propanal + CO₂

NADH + H⁺ + oxygen + 2-iodobenzoate → catechol + NAD⁺ + iodide + CO₂

17 NADPH + 17 H⁺ + 9 malonyl-CoA + acetyl-CoA → 10 coenzyme A + 17 NADP⁺ + 8 H₂O + 9 CO₂ + (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

2-oxoglutarate + oxygen + neopentalenolactone E → succinate + neopentalenolactone F + CO₂

H⁺ + L-lysine → cadaverine + CO₂

ectoine + 2-oxoglutarate + oxygen → 5-hydroxyectoine + succinate + CO₂

H⁺ + 3-decaprenyl-4-hydroxybenzoate → 2-decaprenylphenol + CO₂

2 H⁺ + H₂O + 3-ureidopropanoate → β-alanine + ammonium + CO₂

4α-carboxy-4β,14α-dimethyl-9β,19-cyclo-5α-ergost-24(24¹)-en-3β-ol + NAD⁺ → cycloeucalenone + NADH + CO₂

3 malonyl-CoA + N-methylanthraniloyl-CoA → 3 CO₂ + 4 coenzyme A + 1,3-dihydroxy-N-methylacridone

2-oxoglutarate + 2-chloro-4-methyl-phenoxyacetate + oxygen → glyoxylate + 2-chloro-4-methylphenol + succinate + CO₂

2-oxoglutarate + H⁺ + chloride + oxygen + ambiguine I → H₂O + succinate + ambiguine E + CO₂

H₂O + 2,6-dihydroxynicotinate + oxygen → maleamate + formate + H⁺ + CO₂

3 H⁺ + 3 malonyl-CoA + acetyl-CoA + 1,4,5-trihydroxy-Δ^2,3-protoilludene → 3 CO₂ + 4 coenzyme A + H₂O + melleolide F

2 an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A + 5-chloro-4-hydroxy-2-oxopentanoate → 2 a reduced ferredoxin [iron-sulfur] cluster + H⁺ + 4-chloro-3-hydroxybutyryl-CoA + CO₂

H⁺ + 3,6,8-trimethyl-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline → S-(+)-3,6,8-trimethylallantoin + CO₂

H⁺ + meso-diaminopimelate → L-lysine + CO₂

2 H⁺ + 6-hydroxynicotinate + NADH + oxygen → H₂O + 2,5-dihydroxypyridine + NAD⁺ + CO₂

H⁺ + 1,3-dicarboxyurea → urea-1-carboxylate + CO₂

H₂O + ammonium + ubiquinone-10 → rhodoquinone-10 + CO₂

2 H⁺ + NADH + 5-methylsalicylate + oxygen → H₂O + 4-methylcatechol + NAD⁺ + CO₂

(E)-cinnamoyl-CoA + 4-coumaroyl-diketide + H⁺ → coenzyme A + (1E,6E)-1-(4-hydroxyphenyl)-7-phenylhepta-1,6-diene-3,5-dione + CO₂

11 H⁺ + 5 NADPH + 5 (S)-methylmalonyl-CoA + malonyl-CoA → 2 H₂O + 5 NADP⁺ + 6 coenzyme A + 6 CO₂ + 10-deoxymethynolide

2-oxoglutarate + oxygen + gibberellin A₁₂ → succinate + gibberellin A₁₅ (open lactone form) + CO₂

H⁺ + 3-oxo-palmitate → 2-pentadecanone + CO₂

2-oxoglutarate + oxygen + gibberellin A₂₀ → succinate + gibberellin A₁ + CO₂

carboxynorspermidine + H⁺ → norspermidine + CO₂

(E)-4-coumaroyl-CoA + H⁺ + malonyl-CoA → coenzyme A + 4-coumaroylacetyl-CoA + CO₂

H₂O + chlorophyllide a → methanol + 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + CO₂

11 NADPH + 2 (S)-methylmalonyl-CoA + 22 H⁺ + 9 malonyl-CoA → 11 coenzyme A + 11 NADP⁺ + 11 CO₂ + 5 H₂O + spinosyn macrolactone

H⁺ + Δ⁹-tetrahydrocannabinolate → Δ⁹-tetrahydrocannabinol + CO₂

3-carboxy-9-(methylsulfanyl)-2-oxononanoate + H⁺ → 9-(methylsulfanyl)-2-oxononanoate + CO₂

2-oxoglutarate + H⁺ → succinate semialdehyde + CO₂

2 oxygen + β-fenchene → H₂O + β-fenchocamphorone + CO₂

3-[(4'-methylsulfanyl)butyl]malate + NAD⁺ → NADH + 7-(methylsulfanyl)-2-oxoheptanoate + CO₂

2 H⁺ + siroheme → 2 CO₂ + 12,18-didecarboxysiroheme

1-carboxybiuret + H⁺ → biuret + CO₂

malonate + H⁺ + n Na⁺ → acetate + CO₂ + n Na⁺

NADP⁺ + L-serine → NADPH + 2-aminoacetaldehyde + CO₂

2-oxoglutarate + trans-feruloyl-CoA + oxygen → 6'-hydroxy-trans-feruloyl-CoA + succinate + CO₂

(2R,3S)-3-methylmalate + NAD⁺ → NADH + 2-oxobutanoate + CO₂

2-oxoglutarate + scopoletin + oxygen → fraxetin + succinate + CO₂

H⁺ + 3,4,8,9,10-pentahydroxy-6-oxobenzo[c]chromene-1-carboxylate → urolithin M5 + CO₂

NAD(P)+ + coproporphyrinogen III → 2 CO₂ + NAD(P)H + protoporphyrinogen IX

L-3-cyclohex-2'-enylalanine + chloroethylmalonyl-CoA + acetyl-CoA → 2 coenzyme A + salinosporamide A + H⁺ + CO₂

H⁺ + Na⁺ + (E)-glutaconyl-CoA → crotonyl-CoA + Na⁺ + CO₂

4α-carboxy-5α-cholesta-7,24-dien-3β-ol + NAD⁺ → 5α-cholesta-7,24-dien-3-one + NADH + CO₂

2-oxoglutarate + L-threonine + oxygen → 4-hydroxy-L-threonine + succinate + CO₂

2-amino-3-carboxymuconate-6-semialdehyde → (2Z,4E)-2-amino-6-oxohexa-2,4-dienoate + CO₂

coenzyme A + 2-oxoglutarate + NAD⁺ → NADH + succinyl-CoA + CO₂

NAD(P)H + 2-oxoglutarate + CO₂ ← NAD(P)+ + D-threo-isocitrate

H⁺ + 3-oxo-dodecanoate → 2-undecanone + CO₂

2 an oxidized electron donor + H₂O + 8-carboxy-8-demethylriboflavin 5'-phosphate + L-glutamate → 2 a reduced electron donor + 8-amino-8-demethylriboflavin 5'-phosphate + 2-oxoglutarate + CO₂

2-oxoglutarate + oxygen + gibberellin A₈ → H₂O + H⁺ + succinate + gibberellin A₈-catabolite + CO₂

2-oxoglutarate + validamycin A + oxygen → validamycin B + succinate + CO₂

2 H⁺ + 2 malonyl-CoA + hexanoyl-CoA → 2 coenzyme A + 2 CO₂ + 3,5-dioxodecanoyl-CoA

H⁺ + 3-oxopropanoate → acetaldehyde + CO₂

(2S)-naringenin + 2-oxoglutarate + oxygen → H₂O + H⁺ + succinate + CO₂ + apigenin

H⁺ + oxygen + violaceinate → H₂O + violacein + CO₂

2-oxoglutarate + NADP⁺ + oxygen + gibberellin A₃₆ → 2 CO₂ + NADPH + succinate + gibberellin A₄

L-lysine + oxygen → H₂O + 5-aminopentanamide + CO₂

2 3-amino-4-hydroxybenzoate + 2 oxygen + N-acetyl-L-cysteine + H⁺ → 4 H₂O + grixazone B + CO₂

H⁺ + 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate → 2-methoxy-6-(all-trans-octaprenyl)phenol + CO₂

6 H⁺ + 7 malonyl-CoA → 7 coenzyme A + 7 CO₂ + H₂O + heptaketide pyrone

xanthine + 2-oxoglutarate + oxygen → urate + succinate + CO₂

NADPH + H⁺ + oxygen + (indol-3-yl)pyruvate → H₂O + NADP⁺ + (indol-3-yl)acetate + CO₂

2-oxoglutarate + L-proline + oxygen → cis-4-hydroxy-L-proline + succinate + CO₂

H⁺ + malonyl-CoA + densipoloyl-CoA → coenzyme A + 3-oxo-auricoloyl-CoA + CO₂

2-oxoglutarate + oxygen + gibberellin A₁₅ (open lactone form) → H₂O + succinate + gibberellin A₂₄ + CO₂

(-)threo-iso(homo)₂citrate + NAD⁺ → NADH + 2-oxopimelate + CO₂

H₂O + H⁺ + malonyl-CoA + (S)-1-pyrroline-5-carboxylate → coenzyme A + (2S,5S)-5-carboxymethyl proline + CO₂

2-benzyl-3-oxobutanedioate + H⁺ → 2-oxo-4-phenylbutanoate + CO₂

2-oxoglutarate + oxygen + (2R,3S,4S)-leucodelphinidin → 2 H₂O + delphinidin + H⁺ + succinate + CO₂

H⁺ + 3-oxo-myristate → 2-tridecanone + CO₂

deacetoxycephalosporin C + 2-oxoglutarate + oxygen → succinate + deacetylcephalosporin C + CO₂

4-coumaryl-4-coumarate → (7S)-trans-hinokiresinol + CO₂

H⁺ + (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + oxygen → hydrogen peroxide + 5,10-dihydrophenazine + CO₂

1,4-dihydroxy-2-naphthoate + H⁺ + all-trans-undecaprenyl diphosphate → demethylmenaquinol-11 + diphosphate + CO₂

α-linolenate + hydrogen peroxide + H⁺ → 2 H₂O + 1E,8Z,11Z,14Z-heptadecatetraene + CO₂

2 H₂O + 3-(methylsulfanyl)acryloyl-CoA → coenzyme A + acetaldehyde + methanethiol + CO₂

H₂O + polyneuridine aldehyde → 16-epivellosimine + methanol + CO₂

2-oxoglutarate + 8-hydroxy-salvigenin + oxygen → formaldehyde + pilosin + succinate + CO₂

orotidine 5'-phosphate + H⁺ → UMP + CO₂

H⁺ + anthraniloyl-CoA + 3-oxodecanoate → coenzyme A + H₂O + 2-heptyl-4-quinolone + CO₂

fusicocca-2,10(14)-diene-8β,16-diol + 2-oxoglutarate + oxygen → fusicocca-1,10(14)-diene-3,8β,16-triol + succinate + CO₂

L-homotyrosine + 2-oxoglutarate + oxygen → 3-hydroxy-L-homotyrosine + succinate + CO₂

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate + H⁺ → H₂O + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO₂

NADPH + H⁺ + palmitoleoyl-CoA + (S)-methylmalonyl-CoA → 2 coenzyme A + 2-methyl-octadec-2,9-dienoate + NADP⁺ + CO₂

H⁺ + malonyl-CoA + lignoceroyl-CoA → coenzyme A + 3-oxo-cerotoyl-CoA + CO₂

an oxidized electron donor + H⁺ + 2-(glutathion-S-yl)-2-carboxypropane → a reduced electron donor + 2-(glutathion-S-yl)-propene + CO₂

2 NADPH + 2 bromide + 2 oxygen + 5 H⁺ + protocatechuate → 2 NADP⁺ + 4 H₂O + 3,5-dibromocatechol + CO₂

(+)-dihydromyricetin + 2-oxoglutarate + oxygen → myricetin + H₂O + succinate + CO₂

H⁺ + malonyl-CoA + stearoyl-CoA → coenzyme A + 3-oxoicosanoyl-CoA + CO₂

H₂O + (E)-4-coumaroyl-CoA + H⁺ + malonyl-CoA → 2 coenzyme A + 2 CO₂ + 4-hydroxybenzalacetone

2-oxoglutarate + oxygen + 4'-methoxydehydrocyclopeptine → succinate + CO₂ + (-)-4'-methoxycyclopenine

decanoyl-CoA + S-adenosyl-L-methionine → coenzyme A + S-methyl-5'-thioadenosine + 3-aminotridec-2-en-4-one + CO₂

H₂O + cyanuric acid → biuret + CO₂

H⁺ + Na⁺ + (S)-methylmalonyl-CoA → propanoyl-CoA + Na⁺ + CO₂

2 S-adenosyl-L-methionine + Fe-coproporphyrin III → 2 5'-deoxyadenosine + 2 L-methionine + 2 CO₂ + protoheme

H⁺ + (indol-3-yl)pyruvate → (indol-3-yl)acetaldehyde + CO₂

2 H⁺ + NADH + 5-chlorosalicylate + oxygen → H₂O + NAD⁺ + 4-chlorocatechol + CO₂

pyruvate + H⁺ + phosphate + oxygen → acetyl phosphate + hydrogen peroxide + CO₂

3 H₂O + trimethylaminoacetone → 9 H⁺ + glycine betaine + CO₂

thebaine + 2-oxoglutarate + oxygen → oripavine + formaldehyde + succinate + CO₂

3-hydroxy-2-methylpyridine-4,5-dicarboxylate + H⁺ → 3-hydroxy-2-methylpyridine-5-carboxylate + CO₂

2 H⁺ + 3 malonyl-CoA + H₂O + (E)-4-coumaroyl-CoA → 3 CO₂ + 4 coenzyme A + p-coumaroyltriacetate

3-geranyl-4-hydroxybenzoate → geranylhydroquinone + CO₂

3 H⁺ + cyanate + hydrogencarbonate → 2 CO₂ + ammonium

1,4-dihydroxy-2-naphthoate + H⁺ + all-trans-nonaprenyl diphosphate → demethylmenaquinol-9 + diphosphate + CO₂

prephenate + NAD⁺ → NADH + 3-(4-hydroxyphenyl)pyruvate + CO₂

2-oxoglutarate + H⁺ + chloride + oxygen + 12-epi-fischerindole U → H₂O + succinate + CO₂ + 12-epi-fischerindole G

H⁺ + malonyl-CoA + stearidonoyl-CoA → coenzyme A + (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CO₂

fusicocca-2,10(14)-diene-8β,16-diol + 2-oxoglutarate + oxygen → 8β-hydroxyfusicocca-1,10(14)-diene-16-al + H₂O + succinate + CO₂

2 H⁺ + NADH + 5-methylphenazine-1-carboxylate + oxygen → H₂O + NAD⁺ + pyocyanin + CO₂

3 2-oxoglutarate + 3 H⁺ + 3 oxygen + L-arginine → 2 ethene + 3 H₂O + 7 CO₂ + guanidinium + (S)-1-pyrroline-5-carboxylate + succinate

dehydroprephenate + H⁺ → H₂O + 3-(cyclohexa-1,3-dien-1-yl)-2-oxopropanoate + CO₂

H⁺ + L-serine → ethanolamine + CO₂

2-oxoglutarate + andilesin C + oxygen → H₂O + succinate + anditomin + CO₂

H⁺ + malonyl-CoA + anthraniloyl-CoA → coenzyme A + (2-aminobenzoyl)acetyl-CoA + CO₂

2 H⁺ + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate → thiamine phosphate + diphosphate + CO₂

2-oxoglutarate + oxygen + cyclopeptine → H₂O + succinate + CO₂ + dehydrocyclopeptine

H⁺ + malonyl-CoA + α-linolenoyl-CoA → coenzyme A + (11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA + CO₂

dihydroclavaminate + 2-oxoglutarate + oxygen → H₂O + succinate + clavaminate + CO₂

NADP⁺ + L-allo-threonine → aminoacetone + NADPH + CO₂

3 H⁺ + 3 malonyl-CoA + NADPH + S-adenosyl-L-methionine + acetyl-CoA → 3 CO₂ + 4 coenzyme A + H₂O + S-adenosyl-L-homocysteine + 3-methylorcinaldehyde + NADP⁺

H⁺ + S-methyl-L-methionine → dimethylsulfoniopropanoate-amine + CO₂

2 H⁺ + NAD(P)H + 4-hydroxybenzoate + oxygen → H₂O + NAD(P)+ + hydroquinone + CO₂

2-oxoglutarate + oxygen + gibberellin A₁₂ → succinate + gibberellin A₁₁₀ + CO₂

H₂O + L-phenylalanine + H⁺ + oxygen → hydrogen peroxide + phenylacetaldehyde + ammonium + CO₂

4-phosphooxy-L-threonine + NAD⁺ → NADH + 3-amino-1-hydroxyacetone 1-phosphate + CO₂

NAD⁺ + L-serine → NADH + 2-aminoacetaldehyde + CO₂

3 H⁺ + 3 malonyl-CoA + 3-phenylpropanoyl-CoA → 4 coenzyme A + 4 CO₂ + dihydropinosylvin

4-hydroxy-L-tryptophan + H⁺ → 4-hydroxytryptamine + CO₂

3 H⁺ + 3 malonyl-CoA + NADPH + acetyl-CoA → 3 CO₂ + 4 coenzyme A + H₂O + 6-methylsalicylate + NADP⁺

H⁺ + malonyl-CoA + anthraniloyl-CoA → 2 coenzyme A + 4-hydroxy-2(1H)-quinolone + CO₂

(3E)-2-oxohex-3-enedioate + H⁺ → (2Z)-2-hydroxypenta-2,4-dienoate + CO₂

2 H⁺ + N-(carboxyaminomethyl)urea → N-(aminomethyl)urea + CO₂

N,N-dihydroxyhexahomomethioniate + H⁺ → H₂O + (E)-9-(methylsulfanyl)nonanal oxime + CO₂

2-oxoglutarate + oxygen + gibberellin A₁₉ → succinate + gibberellin A₁₇ + CO₂

2 S-adenosyl-L-methionine + 3 malonyl-CoA + acetyl-CoA → 2 S-adenosyl-L-homocysteine + 3 CO₂ + 4 coenzyme A + 3,5-dimethylorsellinate

2 an oxidized electron donor + 2 H⁺ + H₂O + 4-(3-methylbut-2-enyl)-L-abrine → 2 a reduced electron donor + CO₂ + chanoclavine-I

2-oxoglutarate + oxygen + gibberellin A₂₄ → succinate + gibberellin A₂₅ + CO₂

pyruvate + H⁺ + D-glyceraldehyde 3-phosphate → 1-deoxy-D-xylulose 5-phosphate + CO₂

H⁺ + L-histidine → histamine + CO₂

H⁺ + 3-hexaprenyl-4-amino-5-methoxybenzoate → 2-hexaprenyl-6-methoxyaminobenzene + CO₂

H⁺ + C34-carboxyphthiodiolenone → C33-phthiodiolenone A + CO₂

pyruvate + H⁺ → acetaldehyde + CO₂

an oxidized electron donor + formate + H⁺ → a reduced electron donor + CO₂

2 H⁺ + H₂O + N-carbamoylputrescine → putrescine + ammonium + CO₂

3 H⁺ + 3 malonyl-CoA + dihydro-4-coumaroyl-CoA → 3 CO₂ + 4 coenzyme A + phloretin

2-oxoglutarate + oxygen + gibberellin A₁₇ → succinate + gibberellin A₂₈ + CO₂

(-)-yatein + 2-oxoglutarate + oxygen → (-)-deoxypodophyllotoxin + H₂O + succinate + CO₂

a reduced electron donor + 2-oxoglutarate + preandiloid C + oxygen → an oxidized electron donor + H₂O + succinate + andiconin + CO₂

2 H⁺ + L-2-amino-3-oxobutanoate → aminoacetone + CO₂

2-oxoglutarate + oxygen + gibberellin A₁₅ (open lactone form) → succinate + gibberellin A₃₇ + CO₂

8-O-methyl-13-carboxynorjavanicin → 8-O-methyl-13-hydroxynorjavanicin + CO₂

4-coumaryl-4-coumarate → (7S)-cis-hinokiresinol + CO₂

deoxyamidinoproclavaminate + 2-oxoglutarate + oxygen → amidinoproclavaminate + succinate + CO₂

2-oxoglutarate + oxygen + gibberellin A₁₃ → succinate + gibberellin A₄₃ + CO₂

(-)threo-iso(homo)₃citrate + NAD⁺ → NADH + 2-oxosuberate + CO₂

coenzyme A + pyruvate + NAD⁺ → NADH + acetyl-CoA + CO₂

dihydrotoxoflavin + oxygen → 1-[(6E)-5-hydroxy-1-methyl-1,6-dihydro-1,2,4-triazin-6-ylidene]-3-methylurea + CO₂

H⁺ + 3-methoxy-4-hydroxy-5-all-trans-nonaprenylbenzoate → 2-methoxy-6-(all-trans-nonaprenyl)phenol + CO₂

3-(hydroxyphosphonoylmethyl)malate → H⁺ + deamino α-keto demethylphosphinothricin + CO₂

hydrogen peroxide + arachidate + H⁺ → 2 H₂O + 1-nonadecene + CO₂

2-oxoglutarate + H⁺ + oxygen + (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate → 2 CO₂ + H₂O + succinate + 4-[(E)-2-isocyanoethenyl]phenol

3-(4-hydroxyphenyl)pyruvate + H⁺ → (4-hydroxyphenyl)acetaldehyde + CO₂

2-oxoglutarate + oxygen + (2R,3S,4S)-leucocyanidin → H₂O + (4S)-2,3-dehydro-leucocyanidin + succinate + CO₂

2-oxoglutarate + trans-caffeoyl-CoA + oxygen → 2,4,6-trihydroxycinnamoyl-CoA + succinate + CO₂

2 H⁺ + 3 malonyl-CoA + (E)-4-coumaroyl-CoA → 3 CO₂ + 4 coenzyme A + p-coumaroyltriacetic acid lactone

protocatechuate + H⁺ → catechol + CO₂

glycine + H⁺ + succinyl-CoA → coenzyme A + 5-aminolevulinate + CO₂

L-threonine 3-O-phosphate + H⁺ → (R)-1-amino-2-propanol O-2-phosphate + CO₂

H⁺ + malonyl-CoA + 3,5-dioxodecanoyl-CoA → coenzyme A + 3,5,7-trioxododecanoyl-CoA + CO₂

glutaryl-CoA → 2 H⁺ + crotonyl-CoA + CO₂

lipoamide + 2-oxoglutarate → S-succinyl-dihydrolipoamide + CO₂

H⁺ + malonyl-CoA + salicyl-CoA → 2 coenzyme A + 4-hydroxycoumarin + CO₂

an oxidized electron donor + H⁺ + (S)-2-acetolactate → a reduced electron donor + diacetyl + CO₂

2-oxoglutarate + (S)-mecoprop + oxygen → pyruvate + succinate + 2-methyl-4-chlorophenol + CO₂

4-coumarate + H⁺ → 4-vinylphenol + CO₂

11 NADPH + 18 H⁺ + 8 malonyl-CoA + S-adenosyl-L-methionine + acetyl-CoA → 11 NADP⁺ + 6 H₂O + 8 CO₂ + 9 coenzyme A + S-adenosyl-L-homocysteine + dihydromonacolin L lactone

H⁺ + (3Z)-2-chloro-5-oxohex-3-enedioate → (3Z)-5-chloro-2-oxopent-3-enoate + CO₂

H⁺ + tribromopyrrole-2-carboxylate → 2,3,4-tribromo-1H-pyrrole + CO₂

5-aminoimidazole-4-carboxylate + H⁺ → 4-aminoimidazole + CO₂

11 NADPH + 11 H⁺ + 2 malonyl-CoA + 5 (S)-methylmalonyl-CoA + (2S)-ethylmalonyl-CoA → 11 NADP⁺ + 3 H₂O + 8 coenzyme A + 8 CO₂ + tylactone

2-oxoglutarate + oxygen + 4'-methoxycyclopeptine → H₂O + succinate + CO₂ + 4'-methoxydehydrocyclopeptine

unsaturated archaetidylserine + H⁺ → unsaturated archaetidylethanolamine + CO₂

(E)-5-methyl-2-oxo-3-hex-3-enedioate + H⁺ → (4E)-2-oxo-hex-4-enoate + CO₂

3-sulfopyruvate + H⁺ → sulfoacetaldehyde + CO₂

L-arogenate + NAD⁺ → NADH + L-tyrosine + CO₂

a reduced electron donor + 15-demethoxy-ε-rhodomycinone + H⁺ + oxygen → an oxidized electron donor + H₂O + β-rhodomycinone + CO₂

coenzyme A + an oxidized ferredoxin [iron-sulfur] cluster + 3-methyl-2-oxobutanoate → a reduced ferredoxin [iron-sulfur] cluster + H⁺ + isobutanoyl-CoA + CO₂

2 hydrogen peroxide + 2 H⁺ + Fe-coproporphyrin III → 2 CO₂ + 4 H₂O + protoheme

3 H⁺ + 3 malonyl-CoA + (9Z,12Z,15Z)-hexadeca-9,12,15-trienoyl-CoA → 4 coenzyme A + 4 CO₂ + 5-pentadecatrienyl resorcinol

3-[(3'-methylsulfanyl)propyl]malate + NAD⁺ → NADH + 6-(methylsulfanyl)-2-oxohexanoate + CO₂

oripavine + 2-oxoglutarate + oxygen → morphinone + formaldehyde + succinate + CO₂

3 (R)-methylmalonyl-CoA + 6 NADPH + 9 H⁺ + stearoyl-CoA → 3 coenzyme A + 3 H₂O + 3 CO₂ + 6 NADP⁺ + C27-mycolipanoyl-CoA

trans-cinnamate + H⁺ → styrene + CO₂

coenzyme A + phenylglyoxylate + NAD⁺ → NADH + benzoyl-CoA + CO₂

H⁺ + cannabichromenate → cannabichromene + CO₂

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + H⁺ + malonyl-CoA → coenzyme A + (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + CO₂

C-13²-carboxypyropheophorbide a → CO₂ + pyropheophorbide a

H⁺ + L-dopachrome → 5,6-dihydroxyindole + CO₂

3-phenyl-2-oxopropanoate + oxygen → (2-hydroxyphenyl)acetate + CO₂

2-oxo-3-carboxy-4,5-cyclopropylhex-5-enoate + H⁺ → β-methylenecyclopropyl pyruvate + CO₂

2-oxoglutarate + oxygen + gibberellin A₁₅ (closed lactone form) → succinate + gibberellin A₃₇ (closed lactone form) + CO₂

2 S-adenosyl-L-methionine + coproporphyrinogen III → 2 5'-deoxyadenosine + 2 L-methionine + 2 CO₂ + protoporphyrinogen IX

H⁺ + heptaketide pyrone intermediate → aloesone + CO₂

H⁺ + L-tryptophan + oxygen → ammonium + indole-3-glycol aldehyde + CO₂

2-oxoglutarate + oxygen + 3,7,4'-trimethylquercetin → succinate + 3,7,4'-trimethylquercetagetin + CO₂

3-[(7'-methylsulfanyl)heptyl]malate + NAD⁺ → NADH + 10-(methylsulfanyl)-2-oxodecanoate + CO₂

4α-carboxy,4β,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3β-ol + NAD⁺ → 4α,14α-dimethyl-9β,19-cyclo-5α-cholest-24-en-3-one + NADH + CO₂

(R)-mevalonate diphosphate + ATP → isopentenyl diphosphate + phosphate + ADP + CO₂

2 hydrogen peroxide + palmitate + H⁺ → 3 H₂O + pentadecanal + CO₂

N,N-dihydroxy-L-tyrosine + H⁺ → H₂O + (E)-(4-hydroxyphenyl)acetaldehyde oxime + CO₂

NADH + H⁺ + oxygen + 2-bromobenzoate → catechol + NAD⁺ + bromide + CO₂

2 NADPH + 5 malonyl-CoA + 6 H⁺ + acetyl-CoA + oxygen → 2 NADP⁺ + 3 H₂O + 5 CO₂ + 6 coenzyme A + hexaketide pyrone

2-oxoglutarate + oxygen + gibberellin A₃₇ → H₂O + succinate + gibberellin A₃₆ + CO₂

15 malonyl-CoA + 28 NADPH + 4 (S)-methylmalonyl-CoA + 47 H⁺ + 4-aminobenzoyl-CoA → 15 CO₂ + 16 H₂O + 20 coenzyme A + 28 NADP⁺ + candicinolide

H⁺ + (S)-methylmalonyl-CoA → propanoyl-CoA + CO₂

1-methyl-dAMP + 2-oxoglutarate + oxygen → formaldehyde + succinate + dAMP + CO₂

H⁺ + (R)-methylmalonyl-CoA → propanoyl-CoA + CO₂

2-oxoglutarate + oxygen + gibberellin A₂₀ → succinate + gibberellin A₂₉ + CO₂

coenzyme A + 2-oxoadipate + NAD⁺ → NADH + glutaryl-CoA + CO₂

(R)-malate + NAD⁺ → NADH + pyruvate + CO₂

UMP + 2-oxoglutarate + oxygen → 5'-dehydrouridine + phosphate + succinate + CO₂

H⁺ + (S)-2-acetolactate → (R)-acetoin + CO₂

4 NADH + 4 oxygen + 6 H⁺ + dichlorochromopyrrolate → 2 CO₂ + 4 NAD⁺ + 6 H₂O + dichloro-arcyriaflavin A

DIBOA-β-D-glucoside + 2-oxoglutarate + oxygen → TRIBOA-β-D-glucoside + succinate + CO₂

Se-methyl-Se-L-methionine + H⁺ → dimethylselenopropanoate-amine + CO₂

NAD(P)+ + 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate → 4β-methyl-5α-cholest-7-en-3-one + NAD(P)H + CO₂

H⁺ + (S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline → CO₂ + (S)-(+)-allantoin

2 NADPH + 2 bromide + 2 oxygen + 5 H⁺ + 4-hydroxybenzoate → 2 NADP⁺ + 4 H₂O + 2,4-dibromophenol + CO₂

H⁺ + (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + oxygen → hydrogen peroxide + 5,10-dihydrophenazine-1,6-dicarboxylate + CO₂

2-oxoglutarate + oxygen + gibberellin A₂₅ → succinate + gibberellin A₁₃ + CO₂

(2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate → protoanemonin + chloride + CO₂

thebaine + 2-oxoglutarate + oxygen → neopinone + formaldehyde + succinate + CO₂

3-carboxy-2-hydroxymuconate semialdehyde + H⁺ → (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + CO₂

formate + H⁺ + ATP → H₂O + dATP + CO₂

3 H⁺ + NADPH + bromide + oxygen + 3-bromo-4,5-dihydroxybenzoate → 2 H₂O + NADP⁺ + 3,5-dibromocatechol + CO₂

H⁺ + malonyl-CoA + icosanoyl-CoA → coenzyme A + 3-oxo-behenoyl-CoA + CO₂

H⁺ + (S)-4-hydroxymandelate + oxygen → hydrogen peroxide + 4-hydroxybenzaldehyde + CO₂

H⁺ + malonyl-CoA + linoleoyl-CoA → coenzyme A + (11Z,14Z)-3-oxoicosadienoyl-CoA + CO₂

H⁺ + oxygen + protoviolaceinate → H₂O + CO₂ + proviolacein

2 H⁺ + 2,3-dihydroxybenzoate + NADH + oxygen → H₂O + pyrogallol + NAD⁺ + CO₂

2 H⁺ + H₂O + 3-(carbamoylamino)-2-methylpropanoate → (R)-3-amino-2-methylpropanoate + ammonium + CO₂

(2S)-pinocembrin + 2-oxoglutarate + oxygen → (+)-pinobanksin + succinate + CO₂

H⁺ + 1,4-dihydroxy-6-naphthoate + all-trans-hexaprenyl diphosphate → demethylmenaquinol-6 + diphosphate + CO₂

10 malonyl-CoA + 14 NADPH + 23 H⁺ + acetyl-CoA → 10 CO₂ + 11 coenzyme A + 14 NADP⁺ + 9 H₂O + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate

NADH + H⁺ + oxygen + 2-fluorobenzoate → catechol + NAD⁺ + fluoride + CO₂

2-oxoglutarate + oxygen + gibberellin A₉ → succinate + gibberellin A₅₁ + CO₂

10 malonyl-CoA + 9 H⁺ + H₂O → 10 coenzyme A + 10 CO₂ + 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate

H₂O + (R)-4'-phosphopantothenoyl-L-cysteine + H⁺ → (R)-4'-phosphopantothenate + cysteamine + CO₂

formate + H⁺ + UTP → H₂O + dUTP + CO₂

formate + H⁺ + CTP → H₂O + dCTP + CO₂

an oxidized electron donor + 3-phosphonomethylmalate + H⁺ → a reduced electron donor + 2-oxo-4-phosphonobutanoate + CO₂

(E)-4-coumaroyl-CoA + 2-oxoglutarate + oxygen → 2,4-dihydroxy-trans-cinnamoyl-CoA + succinate + CO₂

1,4-dihydroxy-2-naphthoate + H⁺ + all-trans-hexaprenyl diphosphate → demethylmenaquinol-6 + diphosphate + CO₂

N,N-dihydroxyhomomethionine + H⁺ → H₂O + (E)-4-(methylsulfanyl)butanal oxime + CO₂

2-oxoglutarate + oxygen + gibberellin A₅₃ → succinate + gibberellin₄₄ (open lactone form) + CO₂

H₂O + 3-α(S)-strictosidine → CO₂ + strictosamide

coenzyme A + NAD(P)+ + 3-oxopropanoate → NAD(P)H + acetyl-CoA + CO₂

5-phospho-α-D-ribose 1-diphosphate + H⁺ + 4-hydroxybenzoate → 4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate + diphosphate + CO₂

2-oxoglutarate + L-proline + oxygen → cis-3-hydroxy-L-proline + succinate + CO₂

ferulate + 2-oxoglutarate + oxygen → (E)-6'-hydroxyferulate + succinate + CO₂

deacetoxyvindoline + 2-oxoglutarate + oxygen → 17-O-deacetylvindoline + succinate + CO₂

2 Na⁺ + H⁺ + oxaloacetate → 2 Na⁺ + pyruvate + CO₂

H₂O + 4-coumaroylacetyl-CoA + trans-feruloyl-CoA → 2 coenzyme A + demethoxycurcumin + CO₂

2-oxoglutarate + H⁺ + chloride + oxygen + hapalindole U → H₂O + succinate + hapalindole G + CO₂

1,4-dihydroxy-2-naphthoate + H⁺ + all-trans-dodecaprenyl diphosphate → demethylmenaquinol-12 + diphosphate + CO₂

2-oxoglutarate + oxygen + gibberellin A₂₄ → succinate + gibberellin A₃₆ + CO₂

2-oxoglutarate + 4-chloro-2-methylphenoxyacetate + oxygen → glyoxylate + succinate + 2-methyl-4-chlorophenol + CO₂

2-oxoglutarate + oxygen + gibberellin A₂₄ → 2 CO₂ + succinate + gibberellin A₉

3-(4-hydroxyphenyl)pyruvate + oxygen → homogentisate + CO₂

menaquinone-8 + formate → menaquinol-8 + CO₂

H⁺ + oxalate → formate + CO₂

2 H₂O + 2-(hydroxymethyl)-3-(acetamidomethylene)succinate + H⁺ → acetate + 2-hydroxymethyl-4-oxobutanoate + ammonium + CO₂

(1R,6S)-dihydroxycyclohexa-2,4-diene-1,4-dicarboxylate + NAD⁺ → protocatechuate + NADH + CO₂

4-methyl-2-oxopentanoate + oxygen → 3-hydroxy-3-methylbutanoate + CO₂

pyruvate + H⁺ + trans-2-octenal → (S)-3-acetyloctanal + CO₂

2-oxoglutarate + oxygen + (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate → H₂O + succinate + (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + CO₂

2-oxoglutarate + oxygen + gibberellin A₅₁ → H₂O + H⁺ + succinate + gibberellin A₅₁-catabolite + CO₂

5-guanidino-2-oxopentanoate + H⁺ → 4-guanidinobutyraldehyde + CO₂

NAD⁺ + D-threo-isocitrate → NADH + 2-oxoglutarate + CO₂

H₂O + trans-feruloyl-CoA + feruloylacetyl-CoA → 2 coenzyme A + curcumin + CO₂

3 H⁺ + 3 malonyl-CoA + H₂O + acetyl-CoA → 3 CO₂ + 4 coenzyme A + H₂O + orsellinate + H⁺

H₂O + ADP-5-ethyl-4-methylthiazole-2-carboxylate → H⁺ + 4-methyl-5-(2-phosphooxyethyl)thiazole + AMP + CO₂

phytyl diphosphate + homogentisate + H⁺ → 2-methyl-6-phytyl-1,4-benzoquinol + diphosphate + CO₂

2 H⁺ + N-carbamoylsarcosine + H₂O → sarcosine + ammonium + CO₂

2 2-oxoglutarate + 2 oxygen + pentalenolactone D → 2 succinate + 2 CO₂ + H₂O + pentalenolactone F

2 oxygen + α-fenchene → H₂O + α-fenchocamphorone + CO₂

3 H⁺ + 3 malonyl-CoA + (E)-cinnamoyl-CoA → 4 coenzyme A + 4 CO₂ + pinosylvin

formate + H⁺ → H₂ + CO₂

prephenate + H⁺ → 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO₂

12 H⁺ + 5 NADPH + 6 malonyl-CoA + NADH → 4 H₂O + 5 NADP⁺ + 6 coenzyme A + 6 CO₂ + (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + NAD⁺

3-phenyl-2-oxopropanoate + H⁺ → phenylacetaldehyde + CO₂

prephenate + H⁺ → dihydro-4-hydroxyphenylpyruvate + CO₂

3-hexyl-4-septyloxetan-2-one → (7Z)-pentadec-7-ene + CO₂

3-carboxy-10-(methylsulfanyl)-2-oxodecanoate + H⁺ → 10-(methylsulfanyl)-2-oxodecanoate + CO₂

H⁺ + L-tyrosine → tyramine + CO₂

N, N-dihydroxy-tetrahomomethionine + H⁺ → H₂O + (E)-7-(methyltsulfanyl)heptanal oxime + CO₂

H⁺ + 3-methoxy-4-hydroxy-5-all-trans-heptaprenylbenzoate → 2-methoxy-6-(all-trans-heptaprenyl)phenol + CO₂

H₂O + pyruvate + ubiquinone-6 → acetate + ubiquinol-6 + CO₂

2-oxoglutarate + L-isoleucine + oxygen → (2S,3R,4S)-4-hydroxy-L-isoleucine + succinate + CO₂

H⁺ + (indol-3-yl)acetate → skatole + CO₂

coelenterazine disulfonate dioxetanone → excited-state coelenteramide disulfonate anion + CO₂

hydrogen peroxide + H⁺ + harderoheme III → 2 H₂O + protoheme + CO₂

O-carbamoyl-L-serine + H⁺ → ammonium + 2-aminoprop-2-enoate + CO₂

2 H₂O + 2 H⁺ + N²-succinyl-L-arginine → 2 ammonium + N²-succinyl-L-ornithine + CO₂

3-(2-formyl-6-hydroxy-4-methylphenyl)-8-hydroxy-1,4-dioxonaphthalene-2-carboxylate + L-isoleucine → H₂O + (3aS)-jadomycin A + CO₂

(S)-lactate + oxygen → acetate + H₂O + CO₂

carboxyphosphinopyruvate + H⁺ → 3-(hydroxyphosphinoyl)pyruvate + CO₂

2 H⁺ + 3 malonyl-CoA + isovaleryl-CoA → 3 CO₂ + 4 coenzyme A + 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone

2 H⁺ + NADH + 4-chlorosalicylate + oxygen → H₂O + NAD⁺ + 4-chlorocatechol + CO₂

2 H⁺ + oxygen + oxalate → 2 CO₂ + hydrogen peroxide

2-oxoglutarate + H⁺ + oxygen + luteoforol → 2 H₂O + luteolinidin + succinate + CO₂

H⁺ + malonyl-CoA + (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA → coenzyme A + (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO₂

NAD(P)+ + 4α-carboxy-5α-cholesta-8,24-dien-3β-ol → zymosterone + NAD(P)H + CO₂

oxygen + 2,3-dihydroxyindole → anthranilate + H⁺ + CO₂

2-oxoglutarate + oxygen + gibberellin A₁₂ → succinate + gibberellin A₁₄ + CO₂

(3E)-2-oxohex-3-enedioate + H⁺ → 2-oxopent-4-enoate + CO₂

3 H⁺ + 3 malonyl-CoA + benzoyl-CoA → 3 CO₂ + 4 coenzyme A + 2,4,6-trihydroxybenzophenone

NAD(P)+ + D-gluconate 6-phosphate → D-ribulose 5-phosphate + NAD(P)H + CO₂

2 H⁺ + 1-hydroxy-2-naphthoate + NAD(P)H + oxygen → H₂O + naphthalene-1,2-diol + NAD(P)+ + CO₂

(R)-5-phosphomevalonate + ATP → isopentenyl phosphate + phosphate + ADP + CO₂

3-(3,4-dihydroxyphenyl)pyruvate + H⁺ → 3,4-dihydroxyphenylacetaldehyde + CO₂

5-dehydro-4-deoxy-D-glucarate + H⁺ → H₂O + 2,5-dioxopentanoate + CO₂

H₂O + H⁺ + (Z)-2-methylureidoacrylate peracid → (Z)-2-methyl-peroxyaminoacrylate + ammonium + CO₂

5-hydroxy-leucine + 2-oxoglutarate + oxygen → 5,5-dihydroxy-leucine + succinate + CO₂

H₂O + H⁺ + N-carbobenzyloxy-L-glutamine → benzyl alcohol + L-glutamine + CO₂

6-methylsalicylate + H⁺ → 3-methylphenol + CO₂

4α-carboxy-stigmasta-7,24(24¹)-dien-3β-ol + NAD⁺ → avenastenone + NADH + CO₂

(2-aminoethyl)phosphonate + 2-oxoglutarate + oxygen → (2-amino-1-hydroxyethyl)phosphonate + succinate + CO₂

2 H₂O + E-2-(acetamidomethylidene)succinate + H⁺ → acetate + succinate semialdehyde + ammonium + CO₂

phosphonoacetaldehyde + H⁺ + oxaloacetate → 2-keto-4-hydroxy-5-phosphopentanoate + CO₂

13 NADPH + 21 H⁺ + 9 malonyl-CoA + acetyl-CoA → 10 coenzyme A + 13 NADP⁺ + 8 H₂O + 9 CO₂ + (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

2-oxoglutarate + oxygen + 3,7-dimethylquercetin → succinate + 3,7-dimethylquercetagetin + CO₂

2-oxoglutarate + H⁺ + chloride + oxygen + ambiguine C → H₂O + succinate + ambiguine B + CO₂

12 H⁺ + 6 NADPH + 6 (S)-methylmalonyl-CoA + acetyl-CoA → 6 NADP⁺ + 6 CO₂ + 7 coenzyme A + H₂O + 8,8a-deoxyoleandolide

4-phospho-D-threonate + NAD⁺ → glycerone phosphate + NADH + CO₂

1,4-dihydroxy-2-naphthoate + all-trans-octaprenyl diphosphate → 2-demethylmenaquinone-8 + H⁺ + diphosphate + CO₂

H₂O + (E)-4-coumaroyl-CoA + feruloylacetyl-CoA → 2 coenzyme A + demethoxycurcumin + CO₂

3-decyl-4-undecyloxetan-2-one → (11Z)-tricos-11-ene + CO₂

2 H⁺ + NADPH + oxygen + 4-hydroxyisophthalate → protocatechuate + H₂O + NADP⁺ + CO₂

15 malonyl-CoA + 19 NADPH + 3 (S)-methylmalonyl-CoA + 37 H⁺ + acetyl-CoA → 18 CO₂ + 19 coenzyme A + 19 NADP⁺ + 8 H₂O + decarboxy-dehydroxy-demycosaminyl-nystatin

2-oxoglutarate + oxygen + gibberellin₄₄ (open lactone form) → H₂O + succinate + gibberellin A₁₉ + CO₂

thymine + 2-oxoglutarate + oxygen → 5-hydroxymethyluracil + succinate + CO₂

hydrogen peroxide + H⁺ + Fe-coproporphyrin III → 2 H₂O + harderoheme III + CO₂

proclavaminate + 2-oxoglutarate + oxygen → H₂O + dihydroclavaminate + succinate + CO₂

4 H⁺ + uroporphyrinogen-III → 4 CO₂ + coproporphyrinogen III

N-methyl-Δ¹-pyrrolinium cation + H⁺ + acetonedicarboxylate → 4-(1-methyl-2-pyrrolidinyl)-3-oxobutanoate + CO₂

NADP⁺ + D-threo-isocitrate → NADPH + 2-oxoglutarate + CO₂

3,5-cyclohexadiene-1,2-diol-1-carboxylate + NAD⁺ → NADH + catechol + CO₂

H⁺ + malonyl-CoA + adrenoyl-CoA → coenzyme A + (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO₂

hydrogen peroxide + H⁺ + linoleate → 2 H₂O + 1E,8Z,11Z-heptadecatriene + CO₂

(+)-taxifolin + 2-oxoglutarate + oxygen → H₂O + quercetin + succinate + CO₂

NAD⁺ + 3-chloro-3,5-cyclohexadiene-l,2-diol-1-carboxylate → NADH + 3-chlorocatechol + CO₂

2-oxoglutarate + gardenin B + oxygen → formaldehyde + nevadensin + succinate + CO₂

H₂O + L-tyrosine + oxygen → ammonia + hydrogen peroxide + (4-hydroxyphenyl)acetaldehyde + CO₂

(4-hydroxyphenyl)acetate + H⁺ → 4-methylphenol + CO₂

3 H⁺ + NADPH + bromide + oxygen + 3-bromo-4-hydroxybenzoate → 2 H₂O + NADP⁺ + 2,4-dibromophenol + CO₂

an oxidized electron donor + L-3-cyclohex-2'-enylalanine + H⁺ + chloroethylmalonyl-CoA + acetyl-CoA → 2 coenzyme A + a reduced electron donor + salinosporamide A + CO₂

coenzyme A + 2-oxobutanoate + NAD⁺ → propanoyl-CoA + NADH + CO₂

2-oxoglutarate + oxygen + pentalenolactone D → H₂O + succinate + pentalenolactone E + CO₂

2-oxoglutarate + oxygen + gibberellin A₂₅ → succinate + gibberellin A₄₆ + CO₂

15-demethoxy-ε-rhodomycinone + H⁺ → 15-decarboxymethyl-ε-rhodomycinone + CO₂

3 H⁺ + 3 malonyl-CoA + isovaleryl-CoA → 3 CO₂ + 4 coenzyme A + phlorisovalerophenone

4α-carboxy-ergosta-7,24(24¹)-dien-3β-ol + NAD⁺ → episterone + NADH + CO₂

3-phosphonopyruvate + H⁺ → phosphonoacetaldehyde + CO₂

(2R,6Z)-2-hydroxy-6-(hydroxymethylidene)-2,5-dimethylcyclohex-4-ene-1,3-dione + 2-oxoglutarate + oxygen → H₂O + stipitaldehyde + succinate + CO₂

3 H⁺ + 3 malonyl-CoA + (E)-4-coumaroyl-CoA → 4 coenzyme A + 4 CO₂ + trans-resveratrol

4-methyl-2-oxopentanoate + H⁺ → 3-methylbutanal + CO₂

2'-deoxymugineate + 2-oxoglutarate + oxygen → 3-epihydroxy-2'-deoxymugineate + H⁺ + succinate + CO₂

2 H₂O + urate + oxygen → hydrogen peroxide + CO₂ + (S)-(+)-allantoin

2 glyoxylate + H⁺ → tartronate semialdehyde + CO₂

4-oxaloisocrotonate + H⁺ → 2-oxopent-4-enoate + CO₂

1,4-dihydroxy-2-naphthoate + H⁺ + all-trans-tridecaprenyl diphosphate → demethylmenaquinol-13 + diphosphate + CO₂

2-oxoglutarate + H⁺ + oxygen + gibberellin₄₄ (open lactone form) → H₂O + succinate + gibberellin A₃₈ + CO₂

3-ethyl-2-oxosuccinate + H⁺ → 2-oxovalerate + CO₂

(2S)-dihydrotricetin + 2-oxoglutarate + oxygen → (+)-dihydromyricetin + succinate + CO₂

2-oxoglutarate + oxygen + gibberellin A₅ → succinate + gibberellin A₃ + CO₂

H⁺ + 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate → 6-(all-trans-decaprenyl)-2-methoxy-phenol + CO₂

(2R,3S)-3-isopropylmalate + NAD⁺ → NADH + 4-methyl-2-oxopentanoate + CO₂

2 H⁺ + oxygen + coproporphyrinogen III → 2 H₂O + 2 CO₂ + protoporphyrinogen IX

2-hydroxy-3-oxoadipate + H⁺ → 5-hydroxy-4-oxopentanoate + CO₂

2-amino-4-phosphonobutanoate + H⁺ + CTP → CMP-5'-3-(aminopropyl)phosphonate + diphosphate + CO₂

H₂O + H⁺ + O-ureido-D-serine + ATP → ammonium + phosphate + D-cycloserine + ADP + CO₂

2-oxoglutarate + L-arginine + oxygen → (3S)-3-hydroxy-L-arginine + succinate + CO₂

2-oxovalerate + H⁺ → butan-1-al + CO₂

4-coumaryl-4-coumarate → (7R)-trans-hinokiresinol + CO₂

H₂O + linuron → 3,4-dichloroaniline + N,O-dimethylhydroxylamine + CO₂

H⁺ + L-aspartate → L-alanine + CO₂

3-[(5'-methylsulfanyl)pentyl]malate + NAD⁺ → NADH + 8-(methylsulfanyl)-2-oxooctanoate + CO₂

(3E,5R)-5-carboxy-2-oxohept-3-enedioate + H⁺ → (2Z,4Z)-2-hydroxyhepta-2,4-dienedioate + CO₂

coenzyme A + 4-methyl-2-oxopentanoate + NAD⁺ → NADH + isovaleryl-CoA + CO₂

H⁺ + (2-aminobenzoyl)acetate → 2-aminoacetophenone + CO₂

3-[(6'-methylsulfanyl)hexyl]malate + NAD⁺ → NADH + 9-(methylsulfanyl)-2-oxononanoate + CO₂

2'-deoxymugineate + 2-oxoglutarate + oxygen → mugineate + H⁺ + succinate + CO₂

2-oxoglutarate + L-leucine + oxygen → 5-hydroxy-leucine + succinate + CO₂

L-tryptophan + oxygen → H₂O + (indol-3-yl)acetamide + CO₂

N,N-dihydroxy-L-dihomomethionine + H⁺ → H₂O + (E)-5-(methylsulfanyl)pentanal oxime + CO₂

3,5,7-trioxododecanoyl-CoA → coenzyme A + olivetol + CO₂

N,N-dihydroxy-L-phenylalanine + H⁺ → H₂O + (E)-phenylacetaldehyde oxime + CO₂

3-carboxy-2,5-dihydro-5-oxofuran-2-acetate → (4,5-dihydro-5-oxofuran-2-yl)-acetate + CO₂

2 an oxidized electron donor + H₂O + dimethylsulfonio-2-hydroxybutanoate → 2 a reduced electron donor + dimethylsulfoniopropanoate + CO₂

S-adenosyl-L-methionine + precorrin-6B + H⁺ → S-adenosyl-L-homocysteine + precorrin-7 + CO₂

H⁺ + (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + oxygen → hydrogen peroxide + (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + CO₂

3-dehydrocarnitine + H⁺ → trimethylaminoacetone + CO₂

coenzyme A + 3-methyl-2-oxobutanoate + NAD⁺ → NADH + isobutanoyl-CoA + CO₂

2-oxoglutarate + oxygen + gibberellin A₁₉ → 2 CO₂ + succinate + gibberellin A₂₀

H⁺ + 2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate → 5-(methylsulfanyl)-2-oxopentanoate + CO₂

2 3-phenyl-2-oxopropanoate + 2 ATP + H₂O → 2 diphosphate + 2 AMP + (-)-microperfuranone + CO₂

2-oxoglutarate + 2-hydroxyethylphosphonate + oxygen → 1,2-dihydroxyethylphosphonate + succinate + CO₂

3,4-dihydroxyphthalate + H⁺ → protocatechuate + CO₂

5-phospho-α-D-ribose 1-diphosphate + H⁺ + 4-aminobenzoate → 4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate + diphosphate + CO₂

mugineate + 2-oxoglutarate + oxygen → 3-epihydroxymugineate + succinate + CO₂

5-carboxyvanillate + H⁺ → vanillate + CO₂

N,N-dihydroxy-L-valine + H⁺ → H₂O + (E)-2-methylpropanal-oxime + CO₂

3-carboxy-7-(methylsulfanyl)-2-oxoheptanoate + H⁺ → 7-(methylsulfanyl)-2-oxoheptanoate + CO₂

H⁺ + L-2,4-diaminobutanoate → propane-1,3-diamine + CO₂

2-oxoglutarate + oxygen + (2R,3S,4S)-leucopelargonidin → 2 H⁺ + H₂O + (4S)-2,3-dehydroleucopelargonidin + succinate + CO₂

H⁺ + malonyl-CoA + trans-feruloyl-CoA → coenzyme A + feruloylacetyl-CoA + CO₂

3 an oxidized electron donor + FMN + H₂O + L-glutamate + oxygen → 3 a reduced electron donor + 8-amino-8-demethylriboflavin 5'-phosphate + 2-oxoglutarate + H⁺ + CO₂

hydrogen peroxide + 6-amino-2-oxohexanoate → H₂O + 5-aminopentanoate + CO₂

3 NADPH + 5 malonyl-CoA + 8 H⁺ + acetyl-CoA + oxygen → 3 NADP⁺ + 4 H₂O + 6 coenzyme A + 6 CO₂ + 1,8-dihydroxy-3-methylnaphthalene

(6Z,9Z,12Z,15Z)-3-oxo-2-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]octadeca-6,9,12,15-tetraenoate + H⁺ → hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one + CO₂

2-hydroxy-3-carboxy-6-oxo-hepta-2,4-dienoate + H⁺ → 2-hydroxy-6-oxohepta-2,4-dienoate + CO₂

2-oxoglutarate + L-leucine + oxygen → 4-hydroxy-L-leucine + succinate + CO₂

H⁺ + 1,4-dihydroxy-6-naphthoate + all-trans-octaprenyl diphosphate → demethylmenaquinol-8 + diphosphate + CO₂

3-dodecyl-4-tridecyloxetan-2-one → (13Z)-heptacos-13-ene + CO₂

2-oxoglutarate + (R)-mecoprop + oxygen → pyruvate + succinate + 2-methyl-4-chlorophenol + CO₂

H₂O + H⁺ + pheophorbide a → methanol + CO₂ + pyropheophorbide a

H₂O + 2-keto-6-acetamidocaproate + NAD⁺ → 5-acetamidovalerate + NADH + H⁺ + CO₂

12 H⁺ + 6 NADPH + 6 (S)-methylmalonyl-CoA + propanoyl-CoA → 6 NADP⁺ + 6 CO₂ + 7 coenzyme A + H₂O + 6-deoxyerythronolide B

(R)-3,5-bisphosphomevalonate + H⁺ → isopentenyl phosphate + phosphate + CO₂

NAD⁺ + 5-chloro-3,5-cyclohexadiene-l,2-diol-1-carboxylate → NADH + 4-chlorocatechol + CO₂

H⁺ + UDP-α-D-glucuronate → UDP-α-D-xylose + CO₂

2-oxoglutarate + oxygen + dehydrocyclopeptine → succinate + CO₂ + (-)-cyclopenine

2'-deoxyuridine + 2-oxoglutarate + oxygen → uridine + succinate + CO₂

2-oxoglutarate + oxygen + (S)-atropine → (6S)-hydroxyhyoscyamine + succinate + CO₂

2-oxoglutarate + H⁺ + chloride + oxygen + ambiguine H → H₂O + succinate + ambiguine A + CO₂

2 H⁺ + NAD(P)H + oxygen + 4-aminobenzoate → H₂O + 4-aminophenol + NAD(P)+ + CO₂

N, N-dihydroxytrihomomethionine + H⁺ → H₂O + (E)-6-(methylsulfanyl)hexanal oxime + CO₂

L-arogenate + H⁺ → H₂O + L-phenylalanine + CO₂

2 NAD⁺ + H₂O + trimethylaminoacetone + oxygen → 2 NADH + 3 H⁺ + glycine betaine + CO₂

3 H⁺ + 5 NADPH + 9 malonyl-CoA + H₂O + acetyl-CoA → 10 coenzyme A + 5 NADP⁺ + 9 CO₂ + 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate

H⁺ + carboxyspermidine → spermidine + CO₂

(+)-dihydrokaempferol + 2-oxoglutarate + oxygen → H₂O + H⁺ + succinate + CO₂ + kaempferol

2 H⁺ + H₂O + 5-ureidoimidazole-4-carboxylate → 5-aminoimidazole-4-carboxylate + ammonium + CO₂

H₂O + stipitatonate → stipitatate + H⁺ + CO₂

2-oxoglutarate + L-arginine + oxygen → H₂O + guanidinium + H⁺ + (S)-1-pyrroline-5-carboxylate + succinate + CO₂

2-oxoglutarate + oxygen + FR-900098 → succinate + FR-33289 + CO₂

2-oxoglutarate + oxygen + (2S)-eriodictyol → (+)-taxifolin + succinate + CO₂

formate + H⁺ + GTP → H₂O + dGTP + CO₂

hydrogen peroxide + oleate + H⁺ → 2 H₂O + 1E,8Z-heptadecadiene + CO₂

NAD(P)+ + 4β-carboxy-4α-methyl-5α-cholesta-8,24-dien-3β-ol → 3-dehydro-4-methylzymosterol + NAD(P)H + CO₂

NAD(P)+ + 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol → 3-dehydro-4-methylzymosterol + NAD(P)H + CO₂

H₂O + (E)-4-coumaroyl-CoA + 3-oxooctanoyl-CoA → 2 coenzyme A + 4-coumaroylhexanoylmethane + CO₂

(3S,5S)-carbapenam-3-carboxylate + 2-oxoglutarate + oxygen → (5R)-carbapen-2-em-3-carboxylate + H₂O + succinate + CO₂

2-hydroxyphenazine-1-carboxylate + H⁺ → 2-hydroxyphenazine + CO₂

penicillin N + 2-oxoglutarate + oxygen → deacetoxycephalosporin C + H₂O + succinate + CO₂

3-keto-L-gulonate + H⁺ → L-xylulose + CO₂

2 H⁺ + H₂O + (S)-ureidoglycolate → 2 ammonium + glyoxylate + CO₂

2-oxoglutarate + oxygen + gibberellin A₁ → succinate + gibberellin A₈ + CO₂

4-(methylsulfanyl)-2-oxobutanoate + hydroxyl radical → 2 CO₂ + ethene + methanethiol

H⁺ + oxygen + protodeoxyviolaceinate → H₂O + CO₂ + prodeoxyviolacein

2 malonyl-CoA + H⁺ + trans-caffeoyl-CoA → 2 CO₂ + 3 coenzyme A + hispidin

2 an oxidized electron donor + glycine → 2 a reduced electron donor + hydrogen cyanide + CO₂

2-oxoglutarate + oxygen + pentalenolactone E → succinate + pentalenolactone F + CO₂

3-methyl-2-oxobutanoate + H⁺ → isobutanal + CO₂

2 a reduced ferredoxin [iron-sulfur] cluster + 2 CO₂ + coenzyme M + coenzyme B ← 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 formate + CoB-CoM heterodisulfide

NAD⁺ + 3-ethylmalate → NADH + 2-oxovalerate + CO₂

coenzyme A + an oxidized ferredoxin [iron-sulfur] cluster + 5-chloro-4-hydroxy-2-oxopentanoate → a reduced ferredoxin [iron-sulfur] cluster + 4-chloro-3-hydroxybutyryl-CoA + CO₂

2 H⁺ + salicylate + NADH + oxygen → H₂O + catechol + NAD⁺ + CO₂

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate + H⁺ → (4,5-dihydro-5-oxofuran-2-yl)-acetate + CO₂

H⁺ + 10-carboxy-3-deoxycarminomycin → 13-deoxycarminomycin + CO₂

3 H⁺ + 3 malonyl-CoA + 2-methylbutanoyl-CoA → 3 CO₂ + 4 coenzyme A + phlormethylbutanophenone

hydrogen peroxide + stearate + H⁺ → 2 H₂O + 1-heptadecene + CO₂

H⁺ + (-)-dehydrodiconiferyl acid carboxylate → 4,2'-dihydroxy-3,3'-dimethoxy-5'-(2''-carboxyvinyl)stilbene + CO₂

14 NADPH + 22 H⁺ + 9 malonyl-CoA + acetyl-CoA → 10 coenzyme A + 14 NADP⁺ + 8 H₂O + 9 CO₂ + arachidonate

H⁺ + malonyl-CoA + palmitoyl-CoA → coenzyme A + 3-oxooctadecanoyl-CoA + CO₂

19-oxoandrost-4-ene-3,17-dione + oxygen → H₂O + estrone + CO₂

firefly oxyluciferin-dioxetanone → excited state firefly oxyluciferin + CO₂

H⁺ + malonyl-CoA + γ-linolenoyl-CoA → coenzyme A + 3-oxodihomo γ-linolenoyl-CoA + CO₂

3-(4-hydroxybenzyl)-malate + NAD⁺ → NADH + 4-(4-hydroxyphenyl)-2-oxobutanoate + CO₂

H⁺ + (2S)-ethylmalonyl-CoA → butanoyl-CoA + CO₂

3-carboxy-6-(methylsulfanyl)-2-oxohexanoate + H⁺ → 6-(methylsulfanyl)-2-oxohexanoate + CO₂

3-keto-L-gulonate 6-phosphate + H⁺ → L-xylulose 5-phosphate + CO₂

2 H⁺ + FAD + 1'-carboxy-chondrochloren B → FADH₂ + chondrochloren B + CO₂

NAD⁺ + L-threonine → aminoacetone + NADH + CO₂

methylenomycin C → methylenomycin B + CO₂

3 H⁺ + 3 malonyl-CoA → 3 coenzyme A + 3 CO₂ + phloroglucinol

N3-methylcytosine + 2-oxoglutarate + oxygen → formaldehyde + H⁺ + succinate + cytosine + CO₂

2-oxoglutarate + L-asparagine + oxygen → (3S)-3-hydroxy-L-asparagine + succinate + CO₂

(3E)-2-chloro-5-oxohex-3-enedioate + H⁺ → (3E)-5-chloro-2-oxopent-3-enoate + CO₂

a reduced electron donor + H⁺ + L-tryptophan + oxygen → an oxidized electron donor + H₂O + ammonium + (indol-3-yl)acetaldehyde + CO₂

7 H⁺ + 8 malonyl-CoA → 8 coenzyme A + 8 CO₂ + H₂O + octoketide

S-adenosyl-L-methionine + H⁺ + cobalt-precorrin-6B → S-adenosyl-L-homocysteine + CO₂ + cobalt-precorrin-7

H⁺ + 3-heptaprenyl-4-hydroxybenzoate → 2-heptaprenylphenol + CO₂

5-hydroxy-L-tryptophan + H⁺ → serotonin + CO₂

2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen → glyoxylate + 2,4-dichlorophenol + succinate + CO₂

5 H⁺ + 5 malonyl-CoA → 5 coenzyme A + 5 CO₂ + H₂O + 5,7-dihydroxy-2-methylchromone

2 H⁺ + H₂O + allantoate → ammonium + (S)-ureidoglycine + CO₂

(S)-3-methyl-2-oxopentanoate + H⁺ → 2-methylbutanal + CO₂

D-gluconate 6-phosphate + NADP⁺ → D-ribulose 5-phosphate + NADPH + CO₂

an oxidized electron donor + 1,4-dihydroxy-2-naphthoate + H⁺ → 1,4-naphthoquinone + a reduced electron donor + CO₂

H⁺ + malonyl-CoA + oleoyl-CoA → coenzyme A + 3-oxo-(11Z)-eicos-11-enoyl-CoA + CO₂

2-oxoglutarate + oxygen + gibberellin A₅₃ → succinate + gibberellin A₉₇ + CO₂

NADH + H⁺ + 2-chlorobenzoate + oxygen → catechol + NAD⁺ + chloride + CO₂

2 H⁺ + 3 malonyl-CoA + 7-hydroxylauroyl-CoA → 3 CO₂ + 4 coenzyme A + 2-(8-hydroxy-2-oxotridecyl)-6-oxopyran-4-olate

N-[(R)-pantothenoyl]-L-cysteine + H⁺ → pantetheine + CO₂

H⁺ + malonyl-CoA + docosanoyl-CoA → coenzyme A + 3-oxo-lignoceroyl-CoA + CO₂

2-oxoglutarate + L-enduracididine + oxygen → (3S)-3-hydroxy-L-enduracididine + succinate + CO₂

2 NADH + 2 oxygen + 4 H⁺ + chromopyrrolate → 2 NAD⁺ + 2 CO₂ + 3 H₂O + K-252c

N²,N²-dihydroxy-L-tryptophan + H⁺ → H₂O + (E)-(indol-3-yl)acetaldehyde oxime + CO₂

2 oxygen + coproporphyrinogen III → 2 hydrogen peroxide + 2 CO₂ + protoporphyrinogen IX

2-oxoglutarate + H⁺ + chloride + oxygen + ambiguine L → H₂O + succinate + ambiguine K + CO₂

2-oxoglutarate + L-arginine + oxygen → N^ω-hydroxy-L-arginine + succinate + CO₂

2 H⁺ + 2-oxoglutarate + oxygen + gibberellin A₄₄ (closed lactone form) → succinate + gibberellin A₉₈ + CO₂

H⁺ + malonyl-CoA + arachidonoyl-CoA → coenzyme A + (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO₂

2 H⁺ + 2-oxoglutarate + oxygen → 3 CO₂ + H₂O + ethene

phytyl diphosphate + 2-carboxy-1,4-naphthoquinone + H⁺ → demethylphylloquinone + diphosphate + CO₂

2-oxoglutarate + oxygen + 1-deoxypentalenate → succinate + CO₂ + 1-deoxy-11β-hydroxypentalenate

15 H⁺ + 2 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 7 NADPH + (2S)-ethylmalonyl-CoA → 3 H₂O + 7 NADP⁺ + 8 coenzyme A + 8 CO₂ + tylactone

L-phenylalanine + H⁺ → 2-phenylethylamine + CO₂

2-oxoglutarate + N¹-ethyladenine + oxygen → acetaldehyde + succinate + CO₂ + adenine

3 H⁺ + 3 malonyl-CoA + (E)-cinnamoyl-CoA → 3 CO₂ + 4 coenzyme A + pinocembrin chalcone

coenzyme A + NADP⁺ + 3-oxopropanoate → NADPH + acetyl-CoA + CO₂

6 H⁺ + 6 malonyl-CoA + acetyl-CoA → 7 coenzyme A + 7 CO₂ + H₂O + aloesone

D-gluconate 6-phosphate + NAD⁺ → D-ribulose 5-phosphate + NADH + CO₂

2-oxoglutarate + oxygen + (2S)-eriodictyol → H₂O + luteolin + succinate + CO₂

3 H⁺ + 3 malonyl-CoA + 3-hydroxybenzoyl-CoA → 3 CO₂ + 4 coenzyme A + 2,3',4,6-tetrahydroxybenzophenone

2-oxoglutarate + oxygen + apiforol → 2 H₂O + succinate + apigeninidin + CO₂

H⁺ + monothiocarbonate → hydrogen sulfide + CO₂

H₂O + (E)-4-coumaroyl-CoA + 4-coumaroylacetyl-CoA → 2 coenzyme A + bisdemethoxycurcumin + CO₂

H₂O + L-dopa + oxygen → ammonia + hydrogen peroxide + 3,4-dihydroxyphenylacetaldehyde + CO₂

2-oxoglutarate + oxygen + gibberellin A₃₄ → H₂O + H⁺ + succinate + gibberellin A₃₄-catabolite + CO₂

furan-2,5-dicarboxylate + H⁺ → 2-furoate + CO₂

NAD(P)+ + 4β-carboxy-4α-methyl-5α-cholesta-8-en-3β-ol → NAD(P)H + 4α-methyl-5α-cholesta-8-en-3-one + CO₂

NAD(P)+ + 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol → NAD(P)H + 4α-methyl-5α-cholesta-8-en-3-one + CO₂

2-oxoglutarate + kanamycin B + oxygen → ammonium + 2'-dehydrokanamycin A + succinate + CO₂

L-phenylalanine + oxygen → H₂O + 2-phenylacetamide + CO₂

4-phospho-D-erythronate + NAD⁺ → glycerone phosphate + NADH + CO₂

1,4-dihydroxy-2-naphthoate + H⁺ + all-trans-decaprenyl diphosphate → demethylmenaquinol-10 + diphosphate + CO₂

isochorismate + 2-oxoglutarate + H⁺ → 2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate + CO₂

2-oxoglutarate + L-proline + oxygen → trans-4-hydroxy-L-proline + succinate + CO₂

homogentisate + H⁺ + geranylgeranyl diphosphate → 2-methyl-6-geranylgeranyl-1,4-benzoquinol + diphosphate + CO₂

2-oxoglutarate + H⁺ + chloride + oxygen + 12-epi-hapalindole C → H₂O + succinate + 12-epi-hapalindole E + CO₂

3-α(S)-strictosidine → 2 H₂O + CO₂ + strictosamide

5 H⁺ + 5 malonyl-CoA → 5 coenzyme A + 5 CO₂ + H₂O + 1,3,6,8-naphthalenetetrol

(6S)-hydroxyhyoscyamine + 2-oxoglutarate + oxygen → H₂O + scopolamine + H⁺ + succinate + CO₂

glycine + NAD⁺ + 5,6,7,8-tetrahydrofolate → NADH + ammonium + 5,10-methylenetetrahydropteroyl mono-L-glutamate + CO₂

phenylglyoxylate + H⁺ → benzaldehyde + CO₂

2-oxoglutarate + (R)-dichlorprop + oxygen → pyruvate + 2,4-dichlorophenol + succinate + CO₂

3-dehydro-4-phospho-D-erythronate + H⁺ → glycerone phosphate + CO₂

3-dehydro-4-phospho-L-erythronate + H⁺ → glycerone phosphate + CO₂

3 H⁺ + H₂O + urea-1-carboxylate → 2 ammonium + 2 CO₂

3 H⁺ + phytyl diphosphate + 1,4-dihydroxy-2-naphthoate → demethylphylloquinol + diphosphate + CO₂

2-oxoglutarate + oxygen + N⁶,N⁶,N⁶-trimethyl-L-lysine → succinate + CO₂ + 3-hydroxy-N⁶,N⁶,N⁶-trimethyl-L-lysine

H₂O + ammonium + ubiquinone-9 → rhodoquinone-9 + CO₂

1,4-dihydroxy-2-naphthoate + all-trans-heptaprenyl diphosphate → 2-demethylmenaquinone-7 + H⁺ + diphosphate + CO₂

H₂O + 2-oxoadipate → glutarate + CO₂

2-oxosuberate + H⁺ → 7-oxoheptanoate + CO₂

3 malonyl-CoA + 4 H⁺ + NADPH + (E)-4-coumaroyl-CoA → 3 CO₂ + 4 coenzyme A + H₂O + isoliquiritigenin + NADP⁺

2 pyruvate + H⁺ → (S)-2-acetolactate + CO₂

2-oxoglutarate + oxygen + neopentalenolactone D → H₂O + succinate + neopentalenolactone E + CO₂

(R)-4'-phosphopantothenoyl-L-cysteine + H⁺ → 4'-phosphopantetheine + CO₂

H⁺ + L-aspartate → β-alanine + CO₂

2-oxoglutarate + H⁺ + chloride + oxygen + ambiguine J → H₂O + succinate + ambiguine D + CO₂

2-oxoglutarate + oxygen + gibberellin A₂₈ → succinate + (2βOH)-gibberellin₂₈ + CO₂

4-nonyl-3-octyl-oxetan-2-one → (9Z)-nonadec-9-ene + CO₂

a reduced electron donor + H⁺ + oxygen + 15-demethoxyaclacinomycin T → an oxidized electron donor + H₂O + 10-decarboxymethylaclacinomycin T + CO₂

2 NADPH + 2 H⁺ + 2 oxygen + L-phenylalanine → 2 NADP⁺ + 3 H₂O + (E)-phenylacetaldehyde oxime + CO₂

H₂O + pyruvate + ubiquinone-8 → acetate + ubiquinol-8 + CO₂

H⁺ + oxalyl-CoA → formyl-CoA + CO₂

NAD⁺ + UDP-α-D-glucuronate → NADH + UDP-β-L-threo-pentapyranos-4-ulose + CO₂

H⁺ + 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate → 2-hydroxy-7-methyl-6-oxo-2,4-octadienoate + CO₂

H⁺ + L-serine + palmitoyl-CoA → coenzyme A + 3-dehydrosphinganine + CO₂

2 H⁺ + carbamate → ammonium + CO₂

N,N-dihydroxypentahomomethionine + H⁺ → H₂O + (E)-8-(methylsulfanyl)octanal oxime + CO₂

4-amino-2-(methanethioyl)-5-oxo-3-sulfanylpyrrolidine-2-carboxylate + H⁺ → (5E)-3-amino-4-sulfanyl-5-(sulfanylmethylidene)pyrrolidin-2-one + CO₂

2-oxoglutarate + oxygen + gibberellin A₉ → succinate + gibberellin A₄ + CO₂

2 an oxidized ferredoxin [iron-sulfur] cluster + oxalate → 2 a reduced ferredoxin [iron-sulfur] cluster + 2 CO₂

H₂O + 3-amino-2-butanol + oxygen → 4 CO₂ + ammonium

1,4-dihydroxy-2-naphthoate + H⁺ + geranylgeranyl diphosphate → demethylmenaquinol-4 + diphosphate + CO₂

H₂O + carbonyl sulfide → hydrogen sulfide + CO₂

RedL-KS-dodecanoyl-ACP2-malonyl thioester → RedL-ACP2-β-ketomyristoyl thioester + CO₂

3 H⁺ + 3 malonyl-CoA + isobutanoyl-CoA → 3 CO₂ + 4 coenzyme A + phlorisobutanophenone

ferulate + H⁺ → 4-vinylguaiacol + CO₂

4 malonyl-CoA + 5 H⁺ + NADPH + acetyl-CoA → 4 CO₂ + 5 coenzyme A + 6-hydroxymellein + H₂O + NADP⁺

H₂O + H⁺ + (Z)-3-ureidoacrylate peracid → (Z)-3-peroxyaminoacrylate + ammonium + CO₂

L-arogenate + NADP⁺ → NADPH + L-tyrosine + CO₂

2 malonyl-CoA + (E)-4-coumaroyl-CoA + H⁺ → 2 CO₂ + 3 coenzyme A + bis-noryangonin

an oxidized electron donor + H₂O + carbon monoxide → a reduced electron donor + CO₂

1,4-dihydroxy-2-naphthoate + H⁺ + all-trans-octaprenyl diphosphate → demethylmenaquinol-8 + diphosphate + CO₂

12 H⁺ + 5 NADPH + 6 (S)-methylmalonyl-CoA + malonyl-CoA → 2 H₂O + 5 NADP⁺ + 7 coenzyme A + 7 CO₂ + narbonolide

4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one → excited state fungal oxyluciferin + CO₂

2 L-aspartate + 6 Mg²⁺ + 6 ATP + L-HPG + trans-2,3-epoxyhexanone + L-tryptophan + L-threonine + L-serine → 6 diphosphate + 6 ADP + 6 CO₂ + trans-2,3-epoxyhexanone-ser-thr-D-Trp-asp-asp-D-HPG-S-cdaPS1

hydrogen peroxide + palmitate + H⁺ → 2 H₂O + 1-pentadecene + CO₂

octanoyl-CoA + H⁺ + (2-aminobenzoyl)acetate → coenzyme A + H₂O + 2-heptyl-4-quinolone + CO₂

15 H⁺ + 3 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 7 NADPH → 4 H₂O + 7 NADP⁺ + 8 coenzyme A + 8 CO₂ + protomycinolide IV

thiamine diphosphate + pyruvate + H⁺ → 2-(α-hydroxyethyl)thiamine diphosphate + CO₂

H₂O + O-carbamoyl-L-serine + H⁺ → 2 ammonium + pyruvate + CO₂

2 S-adenosyl-L-methionine + precorrin-6B → 2 S-adenosyl-L-homocysteine + 2 H⁺ + precorrin-8x + CO₂

2 H⁺ + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate → thiamine phosphate + diphosphate + CO₂

2 oxygen + a reduced electron donor + 2-oxoglutarate + fumitremorgin B → an oxidized electron donor + H₂O + verruculogen + succinate + CO₂

H⁺ + cannabidiolate → cannabidiol + CO₂

γ-butyrobetaine + 2-oxoglutarate + oxygen → L-carnitine + succinate + CO₂

3 H⁺ + 3 malonyl-CoA + (E)-4-coumaroyl-CoA → 3 CO₂ + 4 coenzyme A + naringenin chalcone

2 H⁺ + 2 malonyl-CoA + anthraniloyl-CoA → 3 coenzyme A + 3 CO₂ + 2-methyl-4-hydroxyquinoline

2-oxoglutarate + oxygen + codeine → formaldehyde + succinate + CO₂ + morphine

C35-phenolcarboxyphthiodiolenone + H⁺ → C34-phenolphthiodiolenone A + CO₂

uroporphyrinogen-I → 4 H⁺ + 4 CO₂ + coproporphyrinogen I

H⁺ + oxygen + deoxyviolaceinate → H₂O + CO₂ + deoxyviolacein

cyanate + H⁺ + hydrogencarbonate → carbamate + CO₂

2 H⁺ + (2S)-2-amino-3-oxo-4-phosphooxybutanoate → 3-amino-1-hydroxyacetone 1-phosphate + CO₂

2 H⁺ + H₂O + L-citrulline → L-ornithine + ammonium + CO₂

(2S)-naringenin + 2-oxoglutarate + oxygen → (+)-dihydrokaempferol + succinate + CO₂

S-adenosyl-L-methionine + H⁺ → S-adenosyl 3-(methylsulfanyl)propylamine + CO₂

(3E,5R)-5-carboxy-2-oxohept-3-enedioate + H⁺ → (4Z)-2-oxohept-4-enedioate + CO₂

2-hydroxy-3-carboxy-6-methoxy-hexa-2,4-dienoate + H⁺ → 2-hydroxy-6-methoxy-hexa-2,4-dienoate + CO₂

coenzyme A + NAD⁺ + 3-oxopropanoate → NADH + acetyl-CoA + CO₂

NAD(P)+ + 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate → NAD(P)H + 4α-methyl-5α-cholest-7-en-3-one + CO₂

2 H⁺ + FAD + 1'-carboxy-chondrochloren A → FADH₂ + chondrochloren A + CO₂

NAD(P)+ + 3β-hydroxy-4α-methyl-5α-cholest-7-ene-4β-carboxylate → NAD(P)H + 4α-methyl-5α-cholest-7-en-3-one + CO₂

coenzyme A + pyruvate + H⁺ + oxygen → hydrogen peroxide + acetyl-CoA + CO₂

homogentisate + H⁺ + all-trans-nonaprenyl diphosphate → 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinol + diphosphate + CO₂

2-benzyl-3-hydroxybutanedioate + NAD⁺ → NADH + 2-oxo-4-phenylbutanoate + CO₂

an oxidized electron donor + H⁺ + 3-(hydroxyphosphonoylmethyl)malate → a reduced electron donor + deamino α-keto demethylphosphinothricin + CO₂

H⁺ + C32-carboxyphthiodiolenone → C31-phthiodiolenone A + CO₂

7 H⁺ + 8 malonyl-CoA → 8 coenzyme A + 8 CO₂ + H₂O + octoketide 4b

H⁺ + acetoacetate → acetone + CO₂

2 malonyl-CoA + H⁺ + acetyl-CoA → 2 CO₂ + 3 coenzyme A + triacetate lactone

5 H⁺ + 6 malonyl-CoA → 6 coenzyme A + 6 CO₂ + H₂O + hexaketide pyrone

2-oxoglutarate + (S)-dichlorprop + oxygen → pyruvate + 2,4-dichlorophenol + succinate + CO₂

saturated archaetidylserine + H⁺ → saturated archaetidylethanolamine + CO₂

NAD⁺ + (1R,2S)-homoisocitrate → NADH + 2-oxoadipate + CO₂

2-amino-4-carboxypyrimidine + H⁺ + L-serine → H₂O + lathyrine + CO₂

pyruvate + benzoate → 1-phenylpropane-1,2-dione + CO₂

2-oxoglutarate + oxygen + gibberellin A₂₉ → H₂O + H⁺ + succinate + gibberellin A₂₉-catabolite + CO₂

H₂O + premithramycin B lactone → mithramycin DK + CO₂

2-aminomalonate semialdehyde + H⁺ → 2-aminoacetaldehyde + CO₂

(S)-malate + H⁺ → (S)-lactate + CO₂

2 H⁺ + 4-methylsalicylate + NADH + oxygen → H₂O + 4-methylcatechol + NAD⁺ + CO₂

3-dimethylallyl-4-hydroxymandelate + oxygen → H₂O + 3-dimethylallyl-4-hydroxybenzoate + CO₂

H⁺ + L-tryptophan → tryptamine + CO₂

oxygen + 3-dimethylallyl-4-hydroxyphenylpyruvate → 3-dimethylallyl-4-hydroxymandelate + CO₂

2'-deoxyuridine + 2-oxoglutarate + oxygen → 2-deoxyribonolactone + succinate + uracil + CO₂

(2R)-naringenin + 2-oxoglutarate + oxygen → (-)-dihydrokaempferol + succinate + CO₂

O-citryl-L-serine + H⁺ → O-citryl-ethanolamine + CO₂

3 H⁺ + 3 malonyl-CoA + acetyl-CoA + 1,4,5,10,13-pentahydroxy-Δ^2,3-protoilludene → 3 CO₂ + 4 coenzyme A + H₂O + melledonol

L-cysteate + H⁺ → taurine + CO₂

methyloxaloacetate + H⁺ → 2-oxobutanoate + CO₂

22 NADPH + 32 H⁺ + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + heptanoyl-CoA → 10 coenzyme A + 10 CO₂ + 11 H₂O + 22 NADP⁺ + C32-mycoketide-CoA

3-sulfino-L-alanine + H⁺ → hypotaurine + CO₂

(2S,3R)-2-[(2-aminophenyl)amino]-3-carboxy-3-oxopropanoate + H⁺ → 3-[(2-aminophenyl)amino]-2-oxopropanoate + CO₂

H⁺ + UDP-α-D-glucuronate → UDP-D-apiose + CO₂

3 H⁺ + anthranilate + NAD(P)H + oxygen → NAD(P)+ + catechol + ammonium + CO₂

6-dehydroguadinomine B + 2-oxoglutarate + oxygen → guadinomine B + succinate + CO₂

3-[(3Z,6Z,9Z,12Z)-pentadeca-3,6,9,12-tetraen-1-yl]-4-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]oxetan-2-one → hentriaconta-3,6,9,12,15,19,22,25,28-nonaene + CO₂

2 an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A + (indol-3-yl)pyruvate → 2 a reduced ferredoxin [iron-sulfur] cluster + (indol-3 yl)acetyl-CoA + H⁺ + CO₂

aminomalonate + H⁺ → glycine + CO₂

taurine + 2-oxoglutarate + oxygen → 2-aminoacetaldehyde + H⁺ + succinate + sulfite + CO₂

phytanoyl-CoA + 2-oxoglutarate + oxygen → 2-hydroxyphytanoyl-CoA + succinate + CO₂

cis-aconitate → itaconate + CO₂

H⁺ + trans-aconitate → itaconate + CO₂

2-oxoglutarate + H⁺ + oxygen + (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate → 2 CO₂ + H₂O + succinate + 3-[(Z)-2-isocyanoethenyl]-1H-indole

lipoamide + pyruvate + H⁺ → S-acetyldihydrolipoamide + CO₂

4 an oxidized electron donor + 2-amino-3-[(2,5-dihydroxyphenyl)sulfanyl]propanoate + L-cysteine → 4 a reduced electron donor + H₂O + L-firefly luciferin + H⁺ + CO₂

2-oxoglutarate + oxygen + gibberellin A₄ → succinate + gibberellin A₃₄ + CO₂

phosphonoformate → phosphonate + CO₂

3 H⁺ + 3 malonyl-CoA + benzoyl-CoA → 4 coenzyme A + 4 CO₂ + 3,5-dihydroxybiphenyl

a reduced electron donor + 7-chloro-L-tryptophan + oxygen → 2 H₂O + an oxidized electron donor + monodechloroaminopyrrolnitrin + CO₂

vindolidine + 2-oxoglutarate + oxygen → deacetylvindorosine + succinate + CO₂

(2S)-pinocembrin + 2-oxoglutarate + oxygen → H₂O + succinate + CO₂ + chrysin

3 NADPH + 4 H⁺ + oxygen + 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate → 3 NADP⁺ + 5 H₂O + UWM6 + CO₂

oxygen + 3-(4-hydroxyphenyl)pyruvate → 4-hydroxymandelate + CO₂

isoproturon + H₂O + H⁺ → dimethylamine + CO₂ + 4-(propan-2-yl)aniline

malonate + H⁺ → acetate + CO₂

malonyl-CoA + dotriacontanoyl-CoA + H⁺ → 3-oxotetratriacontanoyl-CoA + CO₂ + coenzyme A

3,6,8-trimethyl-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H⁺ → 3,6,8-trimethylallantoin + CO₂

acetyl-CoA + 4 malonyl-CoA + 5 NADPH + 9 H⁺ → 7-methylmellein + 5 coenzyme A + 3 CO₂ + 4 H₂O + 5 NADP⁺

2-ethylhexyl sulfate + oxygen + 2-oxoglutarate → 2-ethylhexanal + succinate + CO₂ + sulfate + H⁺

4-amino-4-deoxyprephenate + NAD⁺ → 3-(4-aminophenyl)pyruvate + CO₂ + NADH + H⁺

monuron + H₂O + H⁺ → dimethylamine + CO₂ + 4-chloroaniline

3-oxo-isoapionate + H⁺ → L-erythrulose + CO₂

malonyl-CoA + (15Z)-tetracosenoyl-CoA + H⁺ → (17Z)-3-oxohexacosenoyl-CoA + CO₂ + coenzyme A

(1S)-1-[(2S)-2-amino-4-methylpentanamido]ethyl(methoxy)phosphinate + 2-oxoglutarate + oxygen → 1-[(2S)-2-amino-4-methylpentanamido]ethenyl(methoxy)phosphinate + succinate + CO₂ + H₂O

L-methionine + 2-oxoglutarate + oxygen → L-methionine S-oxide + succinate + CO₂

2-oxoadipate + oxygen → (R)-2-hydroxyglutarate + CO₂

malonyl-CoA + triacontanoyl-CoA + H⁺ → 3-oxodotriacontanoyl-CoA + CO₂ + coenzyme A

malonyl-CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H⁺ → (8Z,11Z,14Z,17Z,20Z,23Z)-3-oxohexacosahexaenoyl-CoA + CO₂ + coenzyme A

octyl sulfate + oxygen + 2-oxoglutarate → 1-octanal + succinate + CO₂ + sulfate + H⁺

2 oxygen + Latia luciferin + a reduced unknown two electron carrier → Latia oxyluciferin + formate + CO₂ + H₂O + an oxidized unknown electron carrier + H⁺ + hν

Cypridina luciferin + oxygen → hν + Cypridina oxyluciferin + CO₂

H⁺ + 3-all trans-hexaprenyl-4-hydroxy-5-methoxybenzoate → 2-hexaprenyl-6-methoxyphenol + CO₂

L-ascorbate + 1-aminocyclopropane-1-carboxylate + H⁺ + oxygen → 2 H₂O + L-dehydro-ascorbate + ethene + hydrogen cyanide + CO₂

nonyl sulfate + oxygen + 2-oxoglutarate → 1-nonanal + succinate + CO₂ + sulfate + H⁺

methylphosphonate + oxygen + 2-oxoglutarate → (hydroxymethyl)phosphonate + succinate + CO₂

3-(4-hydroxyphenyl)pyruvate + oxygen → (4-hydroxyphenyl)acetate + CO₂

2 (E)-4-coumaroyl-CoA + H₂O + H⁺ + malonyl-CoA → 2 CO₂ + 3 coenzyme A + bisdemethoxycurcumin

2-oxobutanoate + pyruvate + H⁺ → (S)-2-aceto-2-hydroxybutanoate + CO₂

(2S)-2-isopropyl-3-oxosuccinate + H⁺ → 4-methyl-2-oxopentanoate + CO₂

NADP+ + zymosterol intermediate 1c → CO2 + H+ + NADPH + zymosterone

acetyl-CoA + 24 H+ + 8 malonyl-CoA + 16 NADPH → 8 CO2 + 8 coenzyme A + 8 H2O + 16 NADP+ + stearoyl-CoA

4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD+ → 3-dehydro-4-methylzymosterol + CO2 + H+ + NADH

H+ + glycine + lipoamide → CO2 + S8-aminomethyldihydrolipoamide

H+ + glycine + lipoylprotein → CO2 + S8-aminomethyldihydrolipoylprotein

H+ + phosphatidyl-L-serine → CO2 + phosphatidylethanolamine

acetaldehyde + H+ + pyruvate → (R)-acetoin + CO2

2-oxoglutarate + H+ + lipoamide → CO2 + S-succinyl-dihydrolipoamide

acetyl-CoA + 21 H+ + 7 malonyl-CoA + 14 NADPH → 7 CO2 + 7 coenzyme A + 7 H2O + 14 NADP+ + palmitoyl-CoA

acetyl-ACP + carboxyacetyl-ACP + H+ → CO2 + acyl-carrier-protein + acetoacetyl-ACP

carboxyacetyl-ACP + H+ + butanoyl-ACP → CO2 + acyl-carrier-protein + 3-oxohexanoyl-ACP

carboxyacetyl-ACP + H+ + C15718 → CO2 + acyl-carrier-protein + 3-oxooctanoyl-ACP

Reversible reaction (121)

2 an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A + 2-oxoglutarate ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + H⁺ + succinyl-CoA + CO₂

2 H⁺ + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate ↔ 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO₂

orsellinate + H⁺ ↔ orcinol + CO₂

2 H⁺ + FAD + glutaryl-CoA ↔ FADH₂ + crotonyl-CoA + CO₂

H⁺ + L-arginine ↔ agmatine + CO₂

1-carboxyvinyl carboxyphosphonate + H⁺ ↔ 3-(hydroxyphosphinoyl)pyruvate + CO₂

H⁺ + UDP-α-D-galacturonate ↔ UDP-β-L-arabinopyranose + CO₂

2,3-epoxy-2,3-dihydrobenzoyl-CoA ↔ H₂O + 6-hydroxy-3-hexenoyl-CoA + CO₂

2-hydroxychalcone + pyruvate + H⁺ ↔ 3-(2-hydroxyphenyl)-1-phenylpentane-1,4-dione + CO₂

coenzyme A + pyruvate + NADP⁺ ↔ NADPH + acetyl-CoA + CO₂

oxaloacetate + GTP ↔ phosphoenolpyruvate + GDP + CO₂

coenzyme A + an oxidized ferredoxin [iron-sulfur] cluster + pyruvate ↔ a reduced ferredoxin [iron-sulfur] cluster + H⁺ + acetyl-CoA + CO₂

H₂O + dimethylsulfonio-2-hydroxybutanoate ↔ 4 H⁺ + dimethylsulfoniopropanoate + CO₂

(S)-2-aminobutanoate + decanoyl-CoA + H⁺ ↔ coenzyme A + (S)-3-aminotridecan-4-one + CO₂

12 H⁺ + 4 (R)-methylmalonyl-CoA + 8 NADPH + icosanoyl-CoA ↔ 4 coenzyme A + 4 H₂O + 4 CO₂ + 8 NADP⁺ + C32 mycocerosyl-CoA

14 NADPH + 21 H⁺ + 7 (R)-methylmalonyl-CoA + palmitoyl-CoA ↔ 14 NADP⁺ + 7 coenzyme A + 7 H₂O + 7 CO₂ + C37-phthioceranyl-CoA

10 malonyl-CoA + 9 H⁺ ↔ 10 coenzyme A + 10 CO₂ + 2 H₂O + tetracenomycin F2

2 H₂O + carbon disulfide ↔ 2 hydrogen sulfide + CO₂

uracil 5-carboxylate + H⁺ ↔ uracil + CO₂

2 NADPH + 5 malonyl-CoA + 6 H⁺ + acetyl-CoA ↔ 2 NADP⁺ + 3 H₂O + 5 CO₂ + 6 coenzyme A + 2-hydroxy-5-methyl-1-naphthoate

2 H⁺ + NADH + oxygen + phenazine-1-carboxylate ↔ H₂O + phenazin-1-ol + NAD⁺ + CO₂

(E)-4-phenylbut-3-en-2-one + pyruvate + H⁺ ↔ (R)-phenylhexane-2,5-dione + CO₂

2-oxoglutarate + oxygen + gibberellin A₄₄ (closed lactone form) ↔ succinate + gibberellin A₁₉ + CO₂

NADPH + oxygen + gibberellin A₁₂ ↔ NADP⁺ + gibberellin A₉ + CO₂

2 H⁺ + 3 malonyl-CoA + hexanoyl-CoA ↔ 3 CO₂ + 4 coenzyme A + tetraketide pyrone

2 malonyl-CoA + H₂O + hexanoyl-CoA ↔ 2 CO₂ + 3 coenzyme A + OH^- + triketide pyrone

4 H⁺ + 4 malonyl-CoA ↔ 3 coenzyme A + 4 CO₂ + H₂O + (3,5-dihydroxyphenyl)acetyl-CoA

D-dopachrome + H⁺ ↔ 5,6-dihydroxyindole + CO₂

gentisate + H⁺ ↔ hydroquinone + CO₂

an oxidized electron donor + coenzyme A + phenylglyoxylate + H⁺ ↔ a reduced electron donor + benzoyl-CoA + CO₂

2 H⁺ + H₂O + urea ↔ 2 ammonium + CO₂

2 an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A + pyruvate ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + H⁺ + acetyl-CoA + CO₂

H⁺ + (E)-glutaconyl-CoA ↔ crotonyl-CoA + CO₂

2 an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A + 2-oxobutanoate ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + propanoyl-CoA + H⁺ + CO₂

(S)-malate + NADP⁺ ↔ NADPH + pyruvate + CO₂

H⁺ + indole-3-carboxylate ↔ indole + CO₂

γ-resorcylate + H⁺ ↔ resorcinol + CO₂

2,3-dihydroxybenzoate + H⁺ ↔ catechol + CO₂

L-arogenate + NAD(P)+ ↔ NAD(P)H + L-tyrosine + CO₂

anthranilate + H⁺ ↔ aniline + CO₂

H₂O + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + ATP + CO₂ ↔ N⁵-carboxyaminoimidazole ribonucleotide + phosphate + ADP

H₂O + NADP⁺ + 10-formyl-tetrahydrofolate mono-L-glutamate ↔ NADPH + H⁺ + 5,6,7,8-tetrahydrofolate + CO₂

H₂O + 2-oxoglutarate + ATP + CO₂ ↔ 2 H⁺ + oxalosuccinate + phosphate + ADP

3-hydroxy-L-glutamate + H⁺ ↔ 4-amino-3-hydroxybutanoate + CO₂

oxaloacetate + ITP ↔ phosphoenolpyruvate + IDP + CO₂

H⁺ + L-valine ↔ 2-methylpropan-1-amine + CO₂

H⁺ + 4-aminobenzoate ↔ aniline + CO₂

H₂O + puberulonate ↔ puberulate + H⁺ + CO₂

trans-chalcone + pyruvate + H⁺ ↔ (R)-1,3-diphenyl-pentane-1,4-dione + CO₂

oxaloacetate + ATP ↔ phosphoenolpyruvate + ADP + CO₂

H₂O + acetylenedicarboxylate + H⁺ ↔ pyruvate + CO₂

an oxidized ferredoxin [iron-sulfur] cluster + H₂O + carbon monoxide ↔ a reduced ferredoxin [iron-sulfur] cluster + H⁺ + CO₂

formate + NADP⁺ ↔ NADPH + CO₂

3 NADPH + 5 malonyl-CoA + 7 H⁺ + acetyl-CoA ↔ 3 NADP⁺ + 4 H₂O + 5 CO₂ + 6 coenzyme A + 5-methyl-1-naphthoate

diphosphate + oxaloacetate ↔ phosphoenolpyruvate + phosphate + CO₂

2-aryl-2-methylmalonate ↔ 2-arylpropanoate + CO₂

coenzyme A + (S)-3-methyl-2-oxopentanoate + NAD⁺ ↔ NADH + 2-methylbutanoyl-CoA + CO₂

H₂O + H⁺ + urethan ↔ ethanol + ammonium + CO₂

formate + NAD⁺ ↔ NADH + CO₂

2 an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A + (S)-3-methyl-2-oxopentanoate ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + H⁺ + 2-methylbutanoyl-CoA + CO₂

NADPH + oxygen + gibberellin A₁₄ ↔ NADP⁺ + gibberellin A₄ + CO₂

prephenate + H⁺ ↔ H₂O + 3-phenyl-2-oxopropanoate + CO₂

H₂O + pyruvate + ubiquinone-9 ↔ acetate + ubiquinol-9 + CO₂

H₂O + N(α)-benzyloxycarbonyl-L-leucine + H⁺ ↔ benzyl alcohol + L-leucine + CO₂

H₂O + propanoyl-CoA + ATP + CO₂ ↔ (S)-methylmalonyl-CoA + phosphate + ADP

coenzyme A + an oxidized ferredoxin [iron-sulfur] cluster + (indol-3-yl)pyruvate ↔ (indol-3 yl)acetyl-CoA + a reduced ferredoxin [iron-sulfur] cluster + CO₂

an oxidized electron donor + glutaryl-CoA ↔ crotonyl-CoA + a reduced electron donor + CO₂

(E)-dec-3-en-2-one + pyruvate + H⁺ ↔ (S)-3-hexanylhexane-2,5-dione + CO₂

H⁺ ↔ 2-oxoglutarate + CO₂

3 H⁺ + 3 malonyl-CoA + hexanoyl-CoA ↔ 3 coenzyme A + 3 CO₂ + 3,5,7-trioxododecanoyl-CoA

H⁺ + malonyl-CoA ↔ acetyl-CoA + CO₂

2 H⁺ + L-tryptophan + oxygen ↔ ammonia + H₂O + (indol-3-yl)acetaldehyde + CO₂

2 an oxidized ferredoxin [iron-sulfur] cluster + coenzyme A + 4-methyl-2-oxopentanoate ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + H⁺ + isovaleryl-CoA + CO₂

2-oxoglutarate + oxygen + gibberellin A₄₄ (closed lactone form) ↔ succinate + gibberellin A₃₈ + CO₂

4,5-dihydroxyphthalate + H⁺ ↔ protocatechuate + CO₂

L-carnitine + H⁺ ↔ 2-methylcholine + CO₂

(E)-non-3-en-2-one + pyruvate + H⁺ ↔ (S)-3-pentanylhexane-2,5-dione + CO₂

H⁺ + hydrogencarbonate ↔ H₂O + CO₂

12 H⁺ + 4 (R)-methylmalonyl-CoA + 8 NADPH + stearoyl-CoA ↔ 4 coenzyme A + 4 H₂O + 4 CO₂ + 8 NADP⁺ + C30 mycocerosyl-CoA

1,4-dihydroxy-2-naphthoate + H⁺ + all-trans-heptaprenyl diphosphate ↔ demethylmenaquinol-7 + diphosphate + CO₂

carbonic acid ↔ H₂O + CO₂

H⁺ + oxaloacetate ↔ pyruvate + CO₂

3 H⁺ + 3 malonyl-CoA + hexanoyl-CoA ↔ 4 coenzyme A + 4 CO₂ + olivetol

lauroyl-CoA + H⁺ + malonyl-CoA ↔ coenzyme A + 3-oxo-myristoyl-CoA + CO₂

L-tartrate + H⁺ ↔ (R)-glycerate + CO₂

(S)-malate + NAD⁺ ↔ NADH + pyruvate + CO₂

3 (R)-methylmalonyl-CoA + 6 NADPH + 9 H⁺ + icosanoyl-CoA ↔ 3 coenzyme A + 3 H₂O + 3 CO₂ + 6 NADP⁺ + C29-mycolipanoyl-CoA

H₂O + H⁺ + N-benzyloxycarbonylglycine ↔ glycine + benzyl alcohol + CO₂

H⁺ + malonyl-CoA + acetyl-CoA ↔ coenzyme A + acetoacetyl-CoA + CO₂

2 an oxidized ferredoxin [iron-sulfur] cluster + tetrahydrosarcinapterin + H₂O + acetyl-CoA ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H⁺ + coenzyme A + 5-methyl-tetrahydrosarcinapterin + CO₂

2 H⁺ + 2 3-phospho-D-glycerate ↔ H₂O + CO₂ + D-ribulose-1,5-bisphosphate

dihydroxyfumarate + H⁺ ↔ tartronate semialdehyde + CO₂

2 H⁺ + oxalosuccinate + NADP⁺ ↔ NADPH + 2-oxoglutarate + CO₂

pyruvate + formaldehyde + H⁺ ↔ hydroxyacetone + CO₂

2 an oxidized ferredoxin [iron-sulfur] cluster + H₂O + carbon monoxide ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H⁺ + CO₂

H₂O + carbon monoxide ↔ H₂ + CO₂

H⁺ + L-methionine ↔ 3-(methylsulfanyl)propanamine + CO₂

NAD(P)+ + cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate ↔ NAD(P)H + 4-methylcatechol + CO₂

2 NAD(P)H + 2 H⁺ + malonyl-CoA + stearoyl-CoA ↔ 2 NAD(P)+ + coenzyme A + H₂O + icosanoyl-CoA + CO₂

oxalosuccinate + H⁺ ↔ 2-oxoglutarate + CO₂

hydroxypyruvate + H⁺ ↔ glycolaldehyde + CO₂

1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate + NAD⁺ ↔ NADH + 3-methylcatechol + CO₂

H⁺ + malonyl-CoA + myristoyl-CoA ↔ coenzyme A + 3-oxo-palmitoyl-CoA + CO₂

2 malonyl-CoA + H⁺ + isovaleryl-CoA ↔ 2 CO₂ + 3 coenzyme A + 6-isobutyl-4-hydroxy-2-pyrone

(R)-glycerate + NAD(P)+ + CO₂ ↔ 2 H⁺ + NAD(P)H + 2-hydroxy-3-oxosuccinate

thiamine diphosphate + 2-oxoglutarate ↔ succinate-semialdehyde-thiamine PPi + CO₂

coenzyme A + 2-oxoglutarate + NADP⁺ ↔ NADPH + succinyl-CoA + CO₂

β-nicotinate D-ribonucleotide + diphosphate + CO₂ ↔ 2 H⁺ + 5-phospho-α-D-ribose 1-diphosphate + quinolinate

NAD⁺ + (R)-3,3-dimethylmalate ↔ NADH + 3-methyl-2-oxobutanoate + CO₂

H₂O + phenyl phosphate + CO₂ ↔ H⁺ + phosphate + 4-hydroxybenzoate

gallate + H⁺ ↔ pyrogallol + CO₂

2-amino-4-carboxypyrimidine + L-alanine ↔ H₂O + lathyrine + CO₂

2 H⁺ + pentane-1,3,4,5-tetracarboxylate + CO₂ ↔ H₂O + hexane-6-keto-1,3,4,6-tetracarboxylate

2 H₂O + 2 H⁺ + methylenediurea ↔ 2 ammonium + N-(hydroxymethyl)urea + CO₂

3 NADPH + 4 H⁺ + oxygen + 3,5,7,9,11,13,15,17,19-nonaoxohenicosanoate ↔ 3 NADP⁺ + 5 H₂O + homo-UWM6 + CO₂

octanoyl-CoA + H⁺ + 2-(hydroxylamino)benzoylacetate ↔ coenzyme A + H₂O + 2-n-heptyl-4-hydroxyquinoline-N-oxide + CO₂

2 an oxidized ferredoxin [iron-sulfur] cluster + 2 formate + NAD⁺ ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + 2 CO₂ + NADH + H⁺

2-oxoglutarate + glyoxylate + H⁺ ↔ 2-hydroxy-3-oxoadipate + CO₂

2 H⁺ + H₂O + N-carbamoyl-L-aspartate ↔ ammonium + L-aspartate + CO₂

2 H₂O + butan-2-one + ATP + CO₂ ↔ 2 phosphate + 3 H⁺ + 3-oxopentanoate + AMP

(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline ↔ allantoin + CO2

Compound as reactive (14)

Compound as product (747)

Reversible reaction (121)