sugiol





Description


Sugiol is a diterpenoid compound that can be found in various plants such as Juniperus and Salvia species. Biochemically, sugiol has been found to possess various pharmacological properties, including anti-inflammatory, antimicrobial, and antioxidant activities. One study showed that sugiol exhibits a potent anti-inflammatory effect by inhibiting the expression of pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α). It has also been reported to have antibacterial and antifungal activities by disrupting the cell membranes of bacteria and fungi. Furthermore, sugiol has been found to possess antioxidant properties by scavenging free radicals and preventing oxidative damage to cells. This may be beneficial in preventing or managing various diseases such as cancer, diabetes, and cardiovascular diseases, which are associated with oxidative stress. In summary, sugiol is a natural compound with various bioactive properties, and its potential therapeutic applications are currently being studied.


Chemical Formula:
C20H28O2
Molecular Weight:
300.44 Daltons
Monoisotopic Mass:
300.44 Daltons
InChI:
1S/C20H28O2/c1-12(2)13-9-14-15(10-16(13)21)20(5)8-6-7-19(3,4)18(20)11-17(14)22/h9-10,12,18,21H,6-8,11H2,1-5H3/t18-,20+/m0/s1

Synonyms
  • 12-hydroxyabieta-8,11,13-trien-7-one

Databases
KEGG:  C21822
ChEBI:  138961
PubChem (CID):  94162
MetaCyc:  CPD-20267