eumelanin
Description
Eumelanin is a type of melanin pigment that is responsible for producing dark colors in various tissues, including skin, hair, and eyes. It is a polymer that is derived from the amino acid tyrosine and is produced by melanocytes, which are specialized cells located in the skin and hair follicles.
Eumelanin is responsible for the brown and black pigmentation in skin and hair, and is also present in the iris of the eye. It provides protection against ultraviolet (UV) radiation from the sun by absorbing and scattering the UV light, which helps to prevent damage to DNA in skin cells.
Eumelanin is produced in response to UV exposure, and its production is regulated by a complex network of cellular signaling pathways. It has been suggested that variations in eumelanin production and distribution may contribute to differences in skin and hair color among individuals, as well as to differences in susceptibility to UV-induced skin damage and skin cancer.
Eumelanin has also been studied for its potential applications in biotechnology, including its use as a biomaterial for tissue engineering and drug delivery. It has been shown to have biocompatibility and biodegradability, as well as unique optical and electrical properties that make it attractive for use in various applications.
Overall, eumelanin is a complex and important pigment that plays a critical role in protecting the skin and hair from UV radiation, and has potential applications in a variety of fields.
Synonyms
- eu-melanin
Databases
MetaCyc:
CPD-12379