L-dopa

Description

L-DOPA (3,4-dihydroxyphenyl-L-alanine) is an aromatic compound derived from L-tyrosine, used to treat Parkinson's disease, and can be produced microbially using enzymes like tyrosine phenol-lyase (Tpl), tyrosinase, or p-hydroxyphenylacetate 3-hydroxylase (PHAH) [342, 343].

Chemical Formula:

C₉H₁₁NO₄

Molecular Weight:

197.19 Daltons

Monoisotopic Mass:

198.07663287879998 Daltons

SMILES:

C(C(CC1(C=CC(O)=C(O)C=1))[N+])(=O)[O-]

InChI:

1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1

InChIKey:

WTDRDQBEARUVNC-LURJTMIESA-N

Synonyms

DOPA
3-hydroxytyrosine
3,4-dihydroxy-L-phenylalanine
dihydroxyphenylalanine
L-dihydroxy-phenylalanine
levodopa
Dihydroxy-L-phenylalanine
L-beta-(3,4-Dihydroxyphenyl)alanine
3-Hydroxy-L-tyrosine

Databases

MetaCyc: L-DIHYDROXY-PHENYLALANINE

RefMet: DOPA

MetaboLights: MTBLC57504

HMDB: HMDB00181

ChEBI: 57504 15765

PubChem (CID): 6971033 6047

NCI: 118381

CAS: 59-92-7

KEGG: C00355

NIKKAJI: J9.225H

3DMET: B01224

PDB-CCD: DAH

CHEMBL: CHEMBL1009

PupChem (SID): 3648

Seed: cpd00291

MetaNetX: MNXM279

KNApSAcK: C00001357

BiGG: 34dhphe