L-threonine

Description

L-threonine is a relatively expensive amino acid, and in Escherichia coli its intracellular accumulation can induce feedback inhibition of key biosynthetic enzymes, including aspartate kinase, homoserine dehydrogenase, and homoserine kinase, while concurrently activating catabolic enzymes such as threonine aldolase and threonine deaminase. Moreover, L-threonine serves as a direct precursor for 2,5-dimethylpyrazine biosynthesis [358].

Chemical Formula:

C₄H₉NO₃

Molecular Weight:

119.12 Daltons

Monoisotopic Mass:

120.06606819250001 Daltons

SMILES:

CC(O)C([N+])C(=O)[O-]

InChI:

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

InChIKey:

AYFVYJQAPQTCCC-GBXIJSLDSA-N

Synonyms

T
thre
L-thr
threonine
2-amino-3-hydroxybutyric acid

Databases

MetaCyc: THR

RefMet: Threonine

BiGG: thr__L

MetaboLights: MTBLC57926

HMDB: HMDB00167

ChEBI: 57926 16857

PubChem (CID): 6971019 6288

KEGG: C00188

CAS: 72-19-5

PupChem (SID): 3488

CHEMBL: CHEMBL291747

KNApSAcK: C00001394

PDB-CCD: THR

3DMET: B01182

NIKKAJI: J21.883I

MediaDB: compounds/16460/ compounds/184/

Seed: cpd00161

MetaNetX: MNXM142