hypoxanthine

Description

Hypoxanthine is a purine base and a by-product of inosine monophosphate (IMP) biosynthesis and degradation in Escherichia coli. It can be recycled to IMP via the salvage pathway by hypoxanthine phosphoribosyltransferase (HPRT), and its accumulation during fermentation reduces IMP yield [341].

Chemical Formula:

C₅H₄N₄O

Molecular Weight:

136.113 Daltons

Monoisotopic Mass:

136.0385107713 Daltons

SMILES:

C1(NC2(=C(N=1)N=CNC(=O)2))

InChI:

1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)

InChIKey:

FDGQSTZJBFJUBT-UHFFFAOYSA-N

Synonyms

Purine-6-ol

Databases

MetaCyc: HYPOXANTHINE

RefMet: Hypoxanthine

BiGG: hxan

MetaboLights: MTBLC17368

HMDB: HMDB00157

DRUGBANK: DB04076

ChemSpider: 768

PubChem (CID): 790 135398638

ChEBI: 17368

KEGG: C00262

CAS: 68-94-0

NIKKAJI: J1.934H

3DMET: B00078

PDB-CCD: HPA

KNApSAcK: C00001502

CHEMBL: CHEMBL1427

PupChem (SID): 3560