Titer in Flask for L-proline

Strain Production
mg/L
100
200
300
400
500
600
700
800
900
E. coli PM-14

Titer in Fed-Batch for L-proline

Strain Production
mg/L
8000.0
16000.0
24000.0
32000.0
40000.0
E. coli M1
E. coli M1/∆putP
E. coli M1/∆proP
E. coli M1/∆aceA
E. coli M2
E. coli M3
E. coli M4
E. coli M5
E. coli M5/proBE143A
E. coli M6

Volumetric productivity in Fed-Batch for L-proline

Strain Production
mg/L/h
200
400
600
800
1000
E. coli M1
E. coli M1/∆putP
E. coli M1/∆proP
E. coli M1/∆aceA
E. coli M2
E. coli M3
E. coli M4
E. coli M5
E. coli M5/proBE143A
E. coli M6