Escherichia coli Q1(DE3) ThrA S357R Lrp D143G

Ancestors

All strains

Escherichia coli K12

Escherichia coli W1485

Escherichia coli MG1655

Escherichia coli S1

Escherichia coli T1

Escherichia coli Q1

Escherichia coli Q1 (DE3)

Escherichia coli Q1 (DE3) ThrA S357R

Escherichia coli Q1(DE3) ThrA S357R Lrp D143G

Genotype with respect to parental

thrA^mut(T1405A) lrp^mut(A428G)

Genotype with respect to wild type

F⁺ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | ΔsdaA | ΔsdaB ΔtdcG | ΔglyA | λ(DE3) | ThrA^mut(S357R) | thrA^mut(T1405A) lrp^mut(A428G)

Bars (|) indicate differences between strains.

Modifications

Gene	Organism	Modification
thrA	Escherichia coli	Inhibition insensitive
lrp	Escherichia coli	Inhibition insensitive

References

Hemanshu Mundhada, Jose M. Seoane, Konstantin Schneider, Anna Koza, Hanne B. Christensen, Tobias Klein, Patrick V. Phaneuf, Markus Herrgard, Adam M. Feist & Alex T. Nielsen (2016). Increased production of L-serine in Escherichia coli through Adaptive Laboratory Evolution. Metabolic Engineering.