Escherichia coli UR4
Ancestors
Derived strains
Genotype with respect to parental
Pppc::Ptrc, △thrA, △iclR
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | △lacI, yghX::Ptrc-pyrB-pyrC-pyrAA-pyrABfbr(E949*)-pyrK-pyrD-pyrF-pyrE | Δudk | Δudp | △rihA | △rihB | △rihC | tyrR::Ptrc-pyrAA-pyrAB | △argF | Pppc::Ptrc, △thrA, △iclRBars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
|
Overexpression
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Silencing
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Silencing
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Production
| Metabolites | Heterologous | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|---|
| uridine | Titer | 12.3 g/L | 42.9 OD600 | Glucose | 32 h | Flask | [ 202 ] | |
| uridine | Substrate yield | 0.107 g/g of sustrate | 42.9 OD600 | Glucose | 32 h | Flask | [ 202 ] | |
| uracil | Titer | 1.03 g/L | 42.9 OD600 | Glucose | 32 h | Flask | [ 202 ] |
* Inferred from plots using RetroPlot.