Escherichia coli PA132
Ancestors
Genotype with respect to parental
tolR :: ompC
Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | Grows vigorously in the presence of β-alanine | ilvG :: PM1-93-alsScgl, panBC :: PM1-93-panBC | Δglk | ΔavtA | Replacing the start codon of ilvE from ATG to GTG | ΔldhA | ΔpoxB | gltA :: PfliC-gltA | yjiP :: panBC | thrW :: panBC | ykgH :: PM1-93-ilvD | ypjC :: PM1-93-panE | gapC :: gapCcac | sthA :: PM1-93-ppnkcgl | tolR :: ompCBars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
|
Silencing
|
||
|
Overexpression
|
Production
| Metabolites | Heterologous | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|---|
| (R)-pantothenate | Titer | 83.26 g/L | Glucose | Fed-Batch | [ 233 ] | |||
| (R)-pantothenate | Titer | 70.45 g/L | Glucose | Fed-Batch | [ 233 ] | |||
| (R)-pantothenate | Volumetric productivity | 1.74 g/L/h | Glucose | Fed-Batch | [ 233 ] | |||
| (R)-pantothenate | Substrate yield | 0.39 g/g of sustrate | Glucose | Fed-Batch | [ 233 ] | |||
| (R)-pantothenate | Titer | 5.04 g/L | 16.438 OD600* | Glucose | 60 h * | Flask | [ 233 ] |
* Inferred from plots using RetroPlot.