Bo Xiong, Yongduo Zhu, Daoguang Tian, Shuai Jiang, Xiaoguang Fan, Qian Ma, Heyun Wu & Xixian Xie (2021). Flux redistribution of central carbon metabolism for efficient production of l-tryptophan in Escherichia coli. Biotechnology and bioengineering.
Strains
- Escherichia coli SX11
- Escherichia coli SX10
- Escherichia coli SX9
- Escherichia coli SX7
- Escherichia coli SX4
- Escherichia coli SX2
- Escherichia coli SX1
- Escherichia coli SX8
- Escherichia coli SX6
- Escherichia coli SX5
- Escherichia coli SX3
Metabolite production
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L-tryptophan
-
Titer
- 9.9 g/L (Escherichia coli SX1 in Flask)
- 39.1 g/L (Escherichia coli SX1 in Fed-Batch)
- 10.8 g/L (Escherichia coli SX2 in Flask)
- 2.3 g/L (Escherichia coli SX3 in Flask) Substrate yield
- 0.17 g/g of sustrate (Escherichia coli SX1 in Fed-Batch)
- 0.13 g/g of sustrate (Escherichia coli SX1 in Flask)
- 0.148 g/g of sustrate (Escherichia coli SX2 in Flask)