Hyung Seok Choi, Sang Yup Lee, Tae Yong Kim & Han Min Woo (2010). In Silico Identification of Gene Amplification Targets for Improvement of Lycopene Production▿ †. Applied and Environmental Microbiology.

Strains

Plasmids

Metabolite production

all-trans-lycopene
- 3.71 mg/L (Escherichia coli WLGA/pLyc184 in Flask)
- 19.58 mg/L (Escherichia coli WLGB-RPP/pLyc184 in Flask)
- 19.35 mg/L (Escherichia coli WLGB-RPP/pTrcDx-idi-mdh, pLyc184 in Flask)
- 283.0 mg/L (Escherichia coli WLGB-RPP/pTrcDx-idi-mdh, pLyc184 in Fed-Batch)
- 19.78 mg/L (Escherichia coli WLGB-RP/pLyc184 in Flask)
- 23.97 mg/L (Escherichia coli WLGB-RP/pTrcDx-idi-mdh, pLyc184 in Flask)
- 206.7 mg/L (Escherichia coli WLGB-RP/pTrcDx-idi-mdh, pLyc184 in Fed-Batch)
- 8.32 mg/L (Escherichia coli WLGB/pLyc184 in Flask)
- 8.84 mg/L (Escherichia coli WLGB/pTrcDx-tpiA, pLyc184 in Flask)
- 25.46 mg/L (Escherichia coli WLGB/pTrcDx-idi, pLyc184 in Flask)
- 26.77 mg/L (Escherichia coli WLAB/pTrcDx-idi-mdh, pLyc184 in Flask)
- 3.82 mg/L (Escherichia coli WLG/pLyc184 in Flask)
- 4.27 mg/L (Escherichia coli WLAB/pLyc184 in Flask)
- 4.83 mg/L (Escherichia coli WLA/pLyc184 in Flask)
- 5.59 mg/L (Escherichia coli WLB/pLyc184 in Flask)
- 2.52 mg/L (Escherichia coli DH5α/pTrc99A, pLyc184 in Flask)
- 4.95 mg/L (Escherichia coli DH5α/pTrcDx, pLyc184 in Flask)
- 3.25 mg/L (Escherichia coli DH5α/pTrcDx-pfkA, pLyc184 in Flask)
- 5.32 mg/L (Escherichia coli DH5α/pTrcDx-pgi, pLyc184 in Flask)
- 6.94 mg/L (Escherichia coli DH5α/pTrcDx-fbaA, pLyc184 in Flask)
- 6.84 mg/L (Escherichia coli DH5α/pTrcDx-tpiA, pLyc184 in Flask)
- 4.95 mg/L (Escherichia coli DH5α/pTrcDx-icdA, pLyc184 in Flask)
- 9.06 mg/L (Escherichia coli DH5α/pTrcDx-mdh, pLyc184 in Flask)
- 12.85 mg/L (Escherichia coli DH5α/pTrcDx-idi, pLyc184 in Flask)
- 11.5 mg/L (Escherichia coli DH5α/pTrcDx-idi-fbaA, pLyc184 in Flask)
- 10.52 mg/L (Escherichia coli DH5α/pTrcDx-idi-tpiA, pLyc184 in Flask)
- 13.2 mg/L (Escherichia coli DH5α/pTrcDx-idi-mdh, pLyc184 in Flask)
- 1.85 mg/g DCW (Escherichia coli WLGA/pLyc184 in Flask)
- 9.41 mg/g DCW (Escherichia coli WLGB-RPP/pLyc184 in Flask)
- 10.63 mg/g DCW (Escherichia coli WLGB-RPP/pTrcDx-idi-mdh, pLyc184 in Flask)
- 8.8 mg/g DCW (Escherichia coli WLGB-RP/pLyc184 in Flask)
- 12.32 mg/g DCW (Escherichia coli WLGB-RP/pTrcDx-idi-mdh, pLyc184 in Flask)
- 3.65 mg/g DCW (Escherichia coli WLGB/pLyc184 in Flask)
- 3.03 mg/g DCW (Escherichia coli WLGB/pTrcDx-tpiA, pLyc184 in Flask)
- 7.08 mg/g DCW (Escherichia coli WLGB/pTrcDx-idi, pLyc184 in Flask)
- 8.5 mg/g DCW (Escherichia coli WLAB/pTrcDx-idi-mdh, pLyc184 in Flask)
- 1.83 mg/g DCW (Escherichia coli WLG/pLyc184 in Flask)
- 1.99 mg/g DCW (Escherichia coli WLAB/pLyc184 in Flask)
- 2.47 mg/g DCW (Escherichia coli WLA/pLyc184 in Flask)
- 2.6 mg/g DCW (Escherichia coli WLB/pLyc184 in Flask)
- 1.48 mg/g DCW (Escherichia coli DH5α/pTrc99A, pLyc184 in Flask)
- 3.09 mg/g DCW (Escherichia coli DH5α/pTrcDx, pLyc184 in Flask)
- 1.63 mg/g DCW (Escherichia coli DH5α/pTrcDx-pfkA, pLyc184 in Flask)
- 2.73 mg/g DCW (Escherichia coli DH5α/pTrcDx-pgi, pLyc184 in Flask)
- 4.62 mg/g DCW (Escherichia coli DH5α/pTrcDx-fbaA, pLyc184 in Flask)
- 4.89 mg/g DCW (Escherichia coli DH5α/pTrcDx-tpiA, pLyc184 in Flask)
- 2.98 mg/g DCW (Escherichia coli DH5α/pTrcDx-icdA, pLyc184 in Flask)
- 4.83 mg/g DCW (Escherichia coli DH5α/pTrcDx-mdh, pLyc184 in Flask)
- 8.57 mg/g DCW (Escherichia coli DH5α/pTrcDx-idi, pLyc184 in Flask)
- 7.67 mg/g DCW (Escherichia coli DH5α/pTrcDx-idi-fbaA, pLyc184 in Flask)
- 7.51 mg/g DCW (Escherichia coli DH5α/pTrcDx-idi-tpiA, pLyc184 in Flask)
- 9.98 mg/g DCW (Escherichia coli DH5α/pTrcDx-idi-mdh, pLyc184 in Flask)
- 38.47 µg/g DCW/h (Escherichia coli WLGA/pLyc184 in Flask)
- 198.19 µg/g DCW/h (Escherichia coli WLGB-RPP/pLyc184 in Flask)
- 221.52 µg/g DCW/h (Escherichia coli WLGB-RPP/pTrcDx-idi-mdh, pLyc184 in Flask)
- 183.38 µg/g DCW/h (Escherichia coli WLGB-RP/pLyc184 in Flask)
- 256.63 µg/g DCW/h (Escherichia coli WLGB-RP/pTrcDx-idi-mdh, pLyc184 in Flask)
- 75.95 µg/g DCW/h (Escherichia coli WLGB/pLyc184 in Flask)
- 184.08 µg/g DCW/h (Escherichia coli WLGB/pTrcDx-tpiA, pLyc184 in Flask)
- 530.35 µg/g DCW/h (Escherichia coli WLGB/pTrcDx-idi, pLyc184 in Flask)
- 557.73 µg/g DCW/h (Escherichia coli WLAB/pTrcDx-idi-mdh, pLyc184 in Flask)
- 38.03 µg/g DCW/h (Escherichia coli WLG/pLyc184 in Flask)
- 41.51 µg/g DCW/h (Escherichia coli WLAB/pLyc184 in Flask)
- 51.37 µg/g DCW/h (Escherichia coli WLA/pLyc184 in Flask)
- 54.2 µg/g DCW/h (Escherichia coli WLB/pLyc184 in Flask)
- 37.0 µg/g DCW/h (Escherichia coli DH5α/pTrc99A, pLyc184 in Flask)
- 77.25 µg/g DCW/h (Escherichia coli DH5α/pTrcDx, pLyc184 in Flask)
- 40.75 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-pfkA, pLyc184 in Flask)
- 68.25 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-pgi, pLyc184 in Flask)
- 115.5 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-fbaA, pLyc184 in Flask)
- 122.25 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-tpiA, pLyc184 in Flask)
- 74.5 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-icdA, pLyc184 in Flask)
- 120.75 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-mdh, pLyc184 in Flask)
- 214.25 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-idi, pLyc184 in Flask)
- 191.75 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-idi-fbaA, pLyc184 in Flask)
- 187.75 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-idi-tpiA, pLyc184 in Flask)
- 249.5 µg/g DCW/h (Escherichia coli DH5α/pTrcDx-idi-mdh, pLyc184 in Flask)