hisH

Escherichia coli

Sequence

                ATGAACGTGGTGATCCTTGATACCGGCTGCGCCAACCTGAACTCGGTGAAGTCTGCCATTGCGCGTCACGGTTATGAACCCAAAGTCAGCCGTGACCCGGACGTCGTGTTGCTGGCCGATAAACTGTTTTTACCCGGCGTTGGCACTGCGCAAGCGGCGATGGATCAGGTACGTGAGCGCGAGCTGTTTGATCTCATCAAAGCCTGTACCCAACCGGTGCTGGGCATCTGCTTAGGGATGCAACTGCTGGGGCGGCGCAGCGAAGAGAGCAACGGCGTCGACTTGCTGGGCATCATCGACGAAGACGTGCCGAAAATGACCGACTTTGGTCTGCCACTGCCACATATGGGCTGGAACCGCGTTTACCCGCAGGCAGGCAACCGCCTGTTTCAGGGGATTGAAGACGGCGCGTACTTTTACTTTGTTCACAGCTACGCAATGCCGGTCAATCCGTGGACCATCGCCCAGTGTAATTACGGCGAACCGTTCACCGCGGCGGTACAAAAAGATAACTTCTACGGCGTGCAGTTCCACCCGGAGCGTTCTGGTGCCGCTGGTGCTAAGTTGCTGAAAAACTTCCTGGAGATGTGA

hisH and hisF encode the subunits of the heterodimeric imidazole glycerol-phosphate synthase, which catalyzes a step in L-histidine biosynthesis and whose activity can lead to the accumulation of the by-product AICAR [340].

`Gene size:`
`Protein size:`
`Reactions`	R225
`Compounds affected`	L-histidine

Databases

`EraGene:`	2112056
`KEGG:`	eco:b2023