4CL

Arabidopsis thaliana

Sequence
                ATGGCGCCACAAGAACAAGCAGTTTCTCAGGTGATGGAGAAACAGAGCAACAACAACAACAGTGACGTCATTTTCCGATCAAAGTTACCGGATATTTACATCCCGAACCACCTATCTCTCCACGACTACATCTTCCAAAACATCTCCGAATTCGCCACTAAGCCTTGCCTAATCAACGGACCAACCGGCCACGTGTACACTTACTCCGACGTCCACGTCATCTCCCGCCAAATCGCCGCCAATTTTCACAAACTCGGCGTTAACCAAAACGACGTCGTCATGCTCCTCCTCCCAAACTGTCCCGAATTCGTCCTCTCTTTCCTCGCCGCCTCCTTCCGCGGCGCAACCGCCACCGCCGCAAACCCTTTCTTCACTCCGGCGGAGATAGCTAAACAAGCCAAAGCCTCCAACACCAAACTCATAATCACCGAAGCTCGTTACGTCGACAAAATCAAACCACTTCAAAACGACGACGGAGTAGTCATCGTCTGCATCGACGACAACGAATCCGTGCCAATCCCTGAAGGCTGCCTCCGCTTCACCGAGTTGACTCAGTCGACAACCGAGGCATCAGAAGTCATCGACTCGGTGGAGATTTCACCGGACGACGTGGTGGCACTACCTTACTCCTCTGGCACGACGGGATTACCAAAAGGAGTGATGCTGACTCACAAGGGACTAGTCACGAGCGTTGCTCAGCAAGTCGACGGCGAGAACCCGAATCTTTATTTCCACAGCGATGACGTCATACTCTGTGTTTTGCCCATGTTTCATATCTACGCTTTGAACTCGATCATGTTGTGTGGTCTTAGAGTTGGTGCGGCGATTCTGATAATGCCGAAGTTTGAGATCAATCTGCTATTGGAGCTGATCCAGAGGTGTAAAGTGACGGTGGCTCCGATGGTTCCGCCGATTGTGTTGGCCATTGCGAAGTCTTCGGAGACGGAGAAGTATGATTTGAGCTCGATAAGAGTGGTGAAATCTGGTGCTGCTCCTCTTGGTAAAGAACTTGAAGATGCCGTTAATGCCAAGTTTCCTAATGCCAAACTCGGTCAGGGATACGGAATGACGGAAGCAGGTCCAGTGCTAGCAATGTCGTTAGGTTTTGCAAAGGAACCTTTTCCGGTTAAGTCAGGAGCTTGTGGTACTGTTGTAAGAAATGCTGAGATGAAAATAGTTGATCCAGACACCGGAGATTCTCTTTCGAGGAATCAACCCGGTGAGATTTGTATTCGTGGTCACCAGATCATGAAAGGTTACCTCAACAATCCGGCAGCTACAGCAGAGACCATTGATAAAGACGGTTGGCTTCATACTGGAGATATTGGATTGATCGATGACGATGACGAGCTTTTCATCGTTGATCGATTGAAAGAACTTATCAAGTATAAAGGTTTTCAGGTAGCTCCGGCTGAGCTAGAGGCTTTGCTCATCGGTCATCCTGACATTACTGATGTTGCTGTTGTCGCAATGAAAGAAGAAGCAGCTGGTGAAGTTCCTGTTGCATTTGTGGTGAAATCGAAGGATTCGGAGTTATCAGAAGATGATGTGAAGCAATTCGTGTCGAAACAGGTTGTGTTTTACAAGAGAATCAACAAAGTGTTCTTCACTGAATCCATTCCTAAAGCTCCATCAGGGAAGATATTGAGGAAAGATCTGAGGGCAAAACTAGCAAATGGATTGTGA

4CL1 encodes 4-coumarate:CoA ligase 1 from Arabidopsis thaliana, an enzyme that catalyzes the activation of ferulic acid to feruloyl-CoA, a key precursor for curcumin biosynthesis. 4AT denotes an engineered mutant variant of 4CL1 with altered catalytic properties [349].

Synonyms: At4CL1
Gene size:
Protein size:
Reactions R2776 and R1855
Compounds affected curcumin

Databases
EraGene: 2190741
GenBank: U18675
UniProt: Q42524