geoA

Castellaniella defragrans

Sequence

                ATGAACGACACCCAGGATTTCATTTCCGCGCAGGCCGCCGTGCTGCGCCAGGTCGGCGGGCCGCTCGCGGTCGAGCCCGTGCGCATCAGCATGCCCAAAGGCGACGAGGTCTTGATCCGCATCGCCGGCGTGGGCGTCTGCCACACCGACCTGGTGTGCCGCGACGGATTTCCCGTGCCGCTGCCGATCGTGCTCGGCCACGAAGGCTCCGGCACCGTCGAGGCGGTGGGCGAGCAGGTGCGCACGCTCAAGCCCGGCGACCGGGTCGTGCTGTCCTTCAATTCCTGCGGGCATTGCGGCAATTGCCACGACGGCCATCCGTCGAACTGCCTGCAGATGCTGCCCCTGAACTTCGGCGGCGCGCAGCGCGTGGACGGCGGCCAGGTGCTGGACGGCGCCGGCCATCCCGTGCAGAGCATGTTCTTCGGCCAGTCCTCGTTCGGCACGCATGCCGTGGCGCGCGAAATCAATGCGGTCAAGGTCGGCGACGACCTGCCGCTGGAACTGCTGGGCCCGCTGGGCTGCGGCATCCAGACCGGCGCGGGCGCGGCGATCAATTCGCTGGGGATCGGCCCGGGCCAGTCCCTGGCCATCTTCGGCGGTGGCGGCGTCGGCCTGAGCGCGCTGCTGGGCGCGCGCGCCGTCGGGGCGGACCGGGTCGTGGTGATCGAGCCCAATGCCGCGCGCCGGGCCCTGGCCCTGGAACTGGGCGCCAGCCATGCCCTCGACCCGCACGCCGAAGGCGACCTGGTGGCCGCGATCAAGGCGGCCACCGGCGGCGGCGCGACCCACTCGCTGGACACGACGGGCCTGCCCCCGGTCATCGGCAGCGCGATCGCCTGCACCCTGCCGGGCGGCACCGTGGGCATGGTCGGACTGCCGGCGCCCGATGCCCCGGTGCCGGCGACCCTGCTCGATCTGCTGAGCAAAAGCGTCACCCTGCGCCCGATCACCGAGGGCGACGCGGACCCGCAGCGCTTCATCCCGCGCATGCTGGATTTCCATCGCGCGGGCAAATTCCCGTTCGACCGGCTGATCACCCGCTACCGTTTCGACCAGATCAACGAGGCCCTGCACGCCACCGAGAAGGGCGAGGCGATCAAGCCGGTGCTGGTGTTCTGA

GeDH encodes the Castellaniella defragrans geraniol dehydrogenase, which catalyzes the oxidation of geraniol to geranial and is also active toward a broad range of C5–C15 isoprenoid alcohols, including isoprenol, prenol, nerol, perillyl alcohol, and farnesol, yielding the corresponding aldehydes. However, GeDH overexpression in Escherichia coli results in undesired by-product formation from isopentenols, an effect that can be mitigated by reducing expression levels through the use of low-copy-number plasmids [354].

`Synonyms:`	geDH
`Gene size:`
`Protein size:`
`Reactions`	R3113 , R10607 and R10777
`Compounds affected`	geranate

Databases

`EraGene:`	2197924
`GenBank:`	FR669447