crtY

Pantoea ananatis

Sequence

                ATGCAACCGCATTATGATCTGATTCTCGTGGGGGCTGGACTCGCGAATGGCCTTATCGCCCTGCGTCTTCAGCAGCAGCAACCTGATATGCGTATTTTGCTTATCGACGCCGCACCCCAGGCGGGCGGAAATCATACGTGGTCATTTCACCACGATGATTTGACTGAGAGCCAACATCGTTGGATAGCGCCGCTGGTGGTTCATCACTGGCCCGACTATCAGGTGCGCTTTCCCACACGCCGTCGTAAGCTGAACAGCGGCTACTTCTGTATTACTTCTCAGCGTTTCGCTGAGGTTTTACTGCGACAGTTTGGCCCGCACTTGTGGATGGATACCGCGGTCGCAGAGGTTAATGCGGAATCTGTTCGGTTGAAAAAGGGTCAGGTTATCGGTGCCCGCGCGGTGATTGACGGGCGGGGTTATGCGGCAAACTCAGCACTGAGCGTGGGCTTCCAGGCGTTTATTGGCCAGGAATGGCGATTGAGCCGCCCGCATGGTTTATCGTCTCCCATTATCATGGATGCCACGGTCGATCAGCAAAATGGTTATCGCTTCGTGTACAGCCTGCCGCTCTCGCCGACCAGATTGTTAATTGAAGACACGCACTATATCGATAATGCGACATTAGATCCTGAACGCGCGCGGCAAAATATTTGCGACTATGCCGCGCAACAGGGTTGGCAGCTTCAGACTCTGCTGCGTGAAGAACAGGGCGCCTTACCCATTACCCTGTCGGGCAATGCCGACGCATTCTGGCAGCAGCGCCCCCTGGCCTGTAGTGGATTACGTGCCGGTCTGTTCCATCCTACCACCGGCTATTCACTGCCGCTGGCGGTTGCCGTGGCCGACCGCCTGAGCGCACTTGATGTCTTTACGTCGGCCTCAATTCATCAGGCCATTACGCATTTTGCCCGCGAGCGCTGGCAGCAGCAGCGCTTTTTCCGCATGCTGAATCGCATGCTGTTTTTAGCCGGGCCCGCCGATTTACGCTGGCGGGTTATGCAGCGTTTTTATGGTTTACCTGAAGATTTAATTGCCCGTTTTTATGCGGGAAAACTCACGCTGACCGATCGGCTACGTATTCTGAGCGGCAAGCCGCCTGTTCCGGTATTAGCAGCATTGCAAGCCATTATGACGACTCATCGTTAA

crtY encodes lycopene cyclase, which catalyzes the cyclization of lycopene to β-carotene in the carotenoid biosynthesis pathway, and a directed-evolution-derived F49Y/T271I variant increased β-carotene production 3.4-fold by enhancing hydrophobic interactions with lycopene through structural modifications that reduced ligand-binding distances and improved binding stability [344].

`Gene size:`
`Protein size:`
`Reactions`	R2658 and R2657

Databases

`EraGene:`	94460