Escherichia coli DPD4193
Ancestors
Genotype with respect to parental
aroH367 tyrR366 tna-2 lacY5 malT384 aroG397fbr trpE382 Ptrc-tyrA::kanR ΔpheLA
Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | aroH367 tyrR366 tna-2 lacY5 malT384 aroG397fbr trpE382 Ptrc-tyrA::kanR ΔpheLABars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
|
Silencing
|
||
|
Silencing
|
||
|
Silencing
|
||
|
Silencing
|
||
|
Feedback insensitive
|
||
|
Overexpression
|
||
|
Silencing
|
||
|
Silencing
|
||
|
Feedback insensitive
|
Production
| Metabolites | Heterologous | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|---|
| L-tyrosine | Titer | 0.18 g/L | Glucose | Flask | [ 244 ] | |||
| L-tyrosine | Titer | 55.0 g/L | Glucose | Fed-Batch | [ 244 ] | |||
| L-tyrosine | Substrate yield | 0.09 g/g of sustrate | Glucose | Flask | [ 244 ] |
* Inferred from plots using RetroPlot.