Escherichia coli Dmtr-Y

Ancestors

All strains

Escherichia coli K12

Escherichia coli TRTH0709

Escherichia coli TRTH1013

Escherichia coli Dmtr-Y

Genotype with respect to parental

Δmtr yddG

Genotype with respect to wild type

F⁺ (λ) | Plasmid pSV-709 added | ΔtrpR Δtna aroG^fbr trpE^fbrDCBA serA | Plasmid pMEL03 added | Plasmid pMEL03-Y added | Plasmid pMEL03 lost | Δmtr yddG

Bars (|) indicate differences between strains.

Plasmids

pSV-709 (aroG^fbr trpE^fbrDCBA serA)

pMEL03-Y (ppsA tktA yddG)

Modifications

Gene	Organism	Modification
mtr	Escherichia coli	Silencing

Production

Metabolites	Heterologous	Production type	Production	Biomass	Carbon source	Time	Scale	Ref.
L-tryptophan		Substrate yield	19.45 %		Glucose		Fed-Batch	[ 159 ]

* Inferred from plots using RetroPlot.

References

Jian Wang, Li-Kun Cheng, Jing Wang, Qian Liu, Tong Shen & Ning Chen (2013). Genetic engineering of Escherichia coli to enhance production of l-tryptophan. Applied Microbiology and Biotechnology.