Escherichia coli JP201

Ancestors

Derived strains

Genotype with respect to parental

pta::TnphoA′-3


Genotype with respect to wild type
supE44 hsdS20(rB−mB−) ara-14 proA2 lacY1 galK2 rpsL20 xyl-5 mtl-1 | pta::TnphoA′-3

Bars (|) indicate differences between strains.


Modifications
Gene Organism Modification
pta
Silencing

Production
Metabolites Heterologous Production type Production Biomass Carbon source Time Scale Ref.
acetate Substrate yield 0.06 mmol/mmol of sustrate Glucose Flask [ 211 ]
ethanol Substrate yield 0.07 mmol/mmol of sustrate Glucose Flask [ 211 ]
(R)-lactate Substrate yield 1.52 mmol/mmol of sustrate Glucose Flask [ 211 ]
succinate Substrate yield 0.19 mmol/mmol of sustrate Glucose Flask [ 211 ]
pyruvate Substrate yield 0.02 mmol/mmol of sustrate Glucose Flask [ 211 ]
formate Substrate yield 0.08 mmol/mmol of sustrate Glucose Flask [ 211 ]
(R)-lactate Titer 47.0 g/L 0.9 g/L Glucose 150 h Fed-Batch [ 211 ]
(R)-lactate Titer 60.0 g/L 10.0 g/L Glucose 56 h Fed-Batch [ 211 ]
succinate Titer 9.0 g/L 10.0 g/L Glucose 56 h Fed-Batch [ 211 ]
(R)-lactate Volumetric productivity 1.09 g/L/h 10.0 g/L Glucose 56 h Fed-Batch [ 211 ]

* Inferred from plots using RetroPlot.


References