Escherichia coli SX1

Ancestors
Derived strains

Genotype with respect to parental

ΔtnaAB tyrR::Ptrc‐aroGfbr-serAfbr trpE::Ptrc‐trpEfbr yjiV::Ptrc‐trpBA


Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | ΔtnaAB tyrR::Ptrc‐aroGfbr-serAfbr trpE::Ptrc‐trpEfbr yjiV::Ptrc‐trpBA

Bars (|) indicate differences between strains.


Modifications
Gene Organism Modification
Silencing
Silencing
Silencing
Feedback insensitive
Feedback insensitive
Feedback insensitive
Overexpression
Overexpression

Production
Metabolites Heterologous Production type Production Biomass Carbon source Time Scale Ref.
L-tryptophan Titer 9.9 g/L 9.5 g/L Glucose Flask [ 148 ]
L-tryptophan Titer 39.1 g/L Glucose Fed-Batch [ 148 ]
L-tryptophan Substrate yield 0.17 g/g of sustrate Glucose Fed-Batch [ 148 ]
L-tryptophan Substrate yield 0.13 g/g of sustrate 9.5 g/L Glucose Flask [ 148 ]

* Inferred from plots using RetroPlot.


References