Yuanye Chen, Yongfei Liu, Dongqin Ding, Lina Cong & Dawei Zhang (2018). Rational design and analysis of an Escherichia coli strain for high-efficiency tryptophan production. Journal of Industrial Microbiology and Biotechnology.
Strains
- Escherichia coli KW015
- Escherichia coli KW007
- Escherichia coli KW006
- Escherichia coli KW003
- Escherichia coli KW002
- Escherichia coli KW001
- Escherichia coli KW
- Escherichia coli KW009
- Escherichia coli KW019
- Escherichia coli KW020
- Escherichia coli KW021
- Escherichia coli KW004
- Escherichia coli KW005
- Escherichia coli KW008
- Escherichia coli KW011
- Escherichia coli KW012
- Escherichia coli KW013
- Escherichia coli KW014
- Escherichia coli KW016
- Escherichia coli KW018
- Escherichia coli KW022
- Escherichia coli KW017
- Escherichia coli KW023
- Escherichia coli KW010
- Escherichia coli TS-10
Plasmids
Metabolite production
-
acetate
-
Titer
- 3.5 g/L (Escherichia coli KW018 in Fed-Batch)
- 0.5 g/L (Escherichia coli KW022 in Fed-Batch)
-
L-tryptophan
-
Titer
- 0.0 g/L (Escherichia coli W3110 in Flask)
- 0.28 g/L (Escherichia coli KW in Flask)
- 0.5 g/L (Escherichia coli KW001 in Flask)
- 1.0 g/L (Escherichia coli KW002 in Flask)
- 1.2 g/L (Escherichia coli KW003 in Flask)
- 23.0 g/L (Escherichia coli KW003 in Fed-Batch)
- 11.0 g/L (Escherichia coli KW006 in Fed-Batch)
- 0.6 g/L (Escherichia coli KW006 in Flask)
- 0.8 g/L (Escherichia coli KW007 in Flask)
- 0.59 g/L (Escherichia coli KW013 in Flask)
- 0.8 g/L (Escherichia coli KW014 in Flask)
- 1.19 g/L (Escherichia coli KW015 in Flask)
- 1.39 g/L (Escherichia coli KW008 in Flask)
- 1.1 g/L (Escherichia coli KW016 in Flask)
- 1.59 g/L (Escherichia coli KW017 in Flask)
- 2.3 g/L (Escherichia coli KW018 in Flask)
- 37.0 g/L (Escherichia coli KW018 in Fed-Batch)
- 21.6 g/L (Escherichia coli KW022 in Fed-Batch)
- 39.7 g/L (Escherichia coli KW023 in Fed-Batch)
- 1.6 g/L (Escherichia coli KW009 in Flask)
- 1.69 g/L (Escherichia coli KW019 in Flask)
- 1.9 g/L (Escherichia coli KW020 in Flask)
- 1.8 g/L (Escherichia coli KW021 in Flask)
- 0.59 g/L (Escherichia coli KW010 in Flask)
- 0.8 g/L (Escherichia coli KW011 in Flask)
- 1.29 g/L (Escherichia coli KW012 in Flask)
- 1.1 g/L (Escherichia coli KW004 in Flask)
- 0.1 g/L (Escherichia coli KW005 in Flask) Substrate yield
- 0.081 g/g of sustrate (Escherichia coli KW002 in Flask)
- 0.1 g/g of sustrate (Escherichia coli KW003 in Flask)
- 0.16 g/g of sustrate (Escherichia coli KW006 in Fed-Batch)
- 0.11 g/g of sustrate (Escherichia coli KW006 in Flask)
- 0.12 g/g of sustrate (Escherichia coli KW007 in Flask)
- 0.13 g/g of sustrate (Escherichia coli KW013 in Flask)
- 0.13 g/g of sustrate (Escherichia coli KW014 in Flask)
- 0.11 g/g of sustrate (Escherichia coli KW015 in Flask)
- 0.13 g/g of sustrate (Escherichia coli KW008 in Flask)
- 0.12 g/g of sustrate (Escherichia coli KW016 in Flask)
- 0.11 g/g of sustrate (Escherichia coli KW017 in Flask)
- 0.17 g/g of sustrate (Escherichia coli KW018 in Fed-Batch)
- 0.11 g/g of sustrate (Escherichia coli KW018 in Flask)
- 0.135 g/g of sustrate (Escherichia coli KW022 in Fed-Batch)
- 0.167 g/g of sustrate (Escherichia coli KW023 in Fed-Batch)
- 0.11 g/g of sustrate (Escherichia coli KW009 in Flask)
- 0.1 g/g of sustrate (Escherichia coli KW019 in Flask)
- 0.09 g/g of sustrate (Escherichia coli KW020 in Flask)
- 0.08 g/g of sustrate (Escherichia coli KW021 in Flask)
- 0.1 g/g of sustrate (Escherichia coli KW010 in Flask)
- 0.08 g/g of sustrate (Escherichia coli KW011 in Flask)
- 0.09 g/g of sustrate (Escherichia coli KW012 in Flask)
- 0.09 g/g of sustrate (Escherichia coli KW004 in Flask)
- 0.1 g/g of sustrate (Escherichia coli KW005 in Flask) Volumetric productivity
- 1.5 g/L/h (Escherichia coli KW018 in Fed-Batch)
- 1.6 g/L/h (Escherichia coli KW023 in Fed-Batch)