Byoungjin Kim, Robert Binkley, Hyun Uk Kim & Sang Yup Lee (2018). Metabolic engineering of Escherichia coli for the enhanced production of l‐tyrosine. Biotechnology & Bioengineering.

Strains

Plasmids

Metabolite production

L-tryptophan
- 2479.0 mg/L (Escherichia coli BTY5.13 in Flask)
acetate
- 0.88 g/L (Escherichia coli BTY0.13 in Fed-Batch)
- 5.47 g/L (Escherichia coli BTY0.13 in Fed-Batch)
- 0.92 g/L (Escherichia coli BTY2.13 in Fed-Batch)
- 3.88 g/L (Escherichia coli BTY2.13 in Fed-Batch)
- 3.44 g/L (Escherichia coli BTY5.13 in Fed-Batch)
- 1.82 g/L (Escherichia coli BTY5.13 in Fed-Batch)
- 1.46 g/L (Escherichia coli BTY7.13 in Fed-Batch)
- 0.42 g/L (Escherichia coli BTY7.13 in Fed-Batch)
L-tyrosine
- 29.32 g/L (Escherichia coli BTY5.13 in Fed-Batch)
- 26.96 g/L (Escherichia coli BTY5.13 in Fed-Batch)
- 2483.0 mg/L (Escherichia coli BTY7.13 in Flask)
- 25.58 g/L (Escherichia coli BTY7.13 in Fed-Batch)
- 28.73 g/L (Escherichia coli BTY7.13 in Fed-Batch)
- 1083.6 mg/L (Escherichia coli BTY1.1 in Flask)
- 806.0 mg/L (Escherichia coli BTY1.2 in Flask)
- 552.6 mg/L (Escherichia coli BTY1.5 in Flask)
- 942.6 mg/L (Escherichia coli BTY1.10 in Flask)
- 1235.0 mg/L (Escherichia coli BTY1.11 in Flask)
- 1239.0 mg/L (Escherichia coli BTY1.12 in Flask)
- 1896.0 mg/L (Escherichia coli BTY1.13 in Flask)
- 2567.0 mg/L (Escherichia coli BTY2.13 in Flask)
- 43.14 g/L (Escherichia coli BTY2.13 in Fed-Batch)
- 8.57 g/L (Escherichia coli BTY2.13 in Fed-Batch)
- 0.0 mg/L (Escherichia coli BTY0.3 in Flask)
- 0.0 mg/L (Escherichia coli BTY0.4 in Flask)
- 488.4 mg/L (Escherichia coli BTY0.5 in Flask)
- 760.6 mg/L (Escherichia coli BTY0.10 in Flask)
- 923.0 mg/L (Escherichia coli BTY0.11 in Flask)
- 1808.0 mg/L (Escherichia coli BTY0.12 in Flask)
- 2004.0 mg/L (Escherichia coli BTY0.13 in Flask)
- 8.35 g/L (Escherichia coli BTY0.13 in Fed-Batch)
- 11.55 g/L (Escherichia coli BTY0.13 in Fed-Batch)