Ying, Junhui; Lu, Jin; Liu, Qiming; Pan, Yingjie; Bao, Xianfeng; Yin, Junjun & Fu, Bing. Disrupting ribulose-5-phosphate metabolic flux enhances riboflavin production in Escherichia coli BL21(DE3). PLOS One. 2025, 20(11), e0336576.
Strains
- Escherichia coli R203
- Escherichia coli R6
- Escherichia coli R8
- Escherichia coli R9
- Escherichia coli R10
- Escherichia coli R11
- Escherichia coli R12
- Escherichia coli K13
- Escherichia coli R14
- Escherichia coli R15
- Escherichia coli R16
- Escherichia coli R17
- Escherichia coli BL-1
- Escherichia coli BL-8
- Escherichia coli R18
- Escherichia coli R19
- Escherichia coli R20
- Escherichia coli R21
Plasmids
Metabolite production
-
riboflavin
-
Titer
- 2546.35 mg/L (Escherichia coli R19 in Flask)
- 994.0 mg/L (Escherichia coli R9 in Flask)
- 1648.0 mg/L (Escherichia coli R11 in Flask)
- 1972.71 mg/L (Escherichia coli R15 in Flask)
- 2143.39 mg/L (Escherichia coli R17 in Flask)
- 182.65 mg/L (Escherichia coli BL-1 in Flask)
- 247.19 mg/L (Escherichia coli BL-8 in Flask)
- 945.68 mg/L (Escherichia coli R21 in Flask)
- 654.66 mg/L (Escherichia coli R6 in Flask)