adhA

Lactococcus lactis

Sequence

                ATGAAAGCAGCAGTAGTAAGACACAATCCAGATGGTTATGCGGACCTTGTTGAAAAGGAACTTCGAGCAATCAAACCTAATGAAGCTTTGCTTGACATGGAGTATTGTGGAGTCTGTCATACCGATTTGCACGTTGCAGCAGGTGATTATGGCAACAAAGCAGGGACTGTTCTTGGTCATGAAGGAATTGGAATTGTCAAAGAAATTGGAGCTGATGTAAGCTCGCTTCAAGTTGGTGATCGGGTTTCAGTGGCTTGGTTCTTTGAAGGATGTGGTCACTGTGAATACTGTGTATCTGGTAATGAAACTTTTTGTCGAGAAGTTAAAAATGCAGGATATTCAGTTGATGGCGGAATGGCTGAAGAAGCAATTGTTGTTGCCGATTATGCTGTCAAAGTTCCTGACGGACTTGACCCAATTGAAGCTAGCTCAATTACTTGTGCTGGAGTAACAACTTACAAAGCAATCAAAGTATCAGGAGTAAAACCTGGTGATTGGCAAGTAATTTTTGGTGCTGGAGGACTTGGAAATTTAGCAATTCAATATGCTAAAAATGTTTTTGGAGCAAAAGTAATTGCTGTTGATATTAATCAAGATAAATTAAATTTAGCTAAAAAAATTGGAGCTGATGTGATTATCAATTCTGGTGATGTAAATCCAGTTGATGAAATTAAAAAAATAACTGGCGGCTTAGGGGTGCAAAGTGCAATAGTTTGTGCTGTTGCAAGGATTGCTTTTGAACAAGCGGTTGCTTCTTTGAAACCTATGGGCAAAATGGTTGCTGTGGCACTTCCCAATACTGAGATGACTTTATCAGTTCCAACAGTTGTTTTTGACGGAGTGGAGGTTGCAGGTTCACTTGTCGGAACAAGACTTGACTTGGCAGAAGCTTTTCAATTTGGAGCAGAAGGTAAGGTAAAACCAATTGTTGCGACACGCAAACTGGAAGAAATCAATGATATTATTGATGAAATGAAGGCAGGAAAAATTGAAGGCCGAATGGTCATTGATTTTACTAAATAA

The adhA gene encodes an alcohol dehydrogenase from Lactococcus lactis that catalyzes the NADH-dependent reduction of isobutyraldehyde to isobutanol in the isobutanol biosynthesis pathway. Its heterologous expression in Escherichia coli completes the terminal step of the pathway, enabling efficient isobutanol production [356].

`Gene size:`
`Protein size:`
`Reactions`	R774 , R250 , R77 , R1 , R157 , R694 , R78 , R324 , R749 , R287 , R43 , R1196 and R1197
`Compounds affected`	isobutanol

Databases

`EraGene:`	1065052