xfpk

Bifidobacterium adolescentis

Sequence

                ATGACGAGTCCTGTTATTGGCACCCCTTGGAAGAAGCTGAACGCTCCGGTTTCCGAGGAAGCTATCGAAGGCGTGGATAAGTACTGGCGCGCAGCCAACTACCTCTCCATCGGCCAGATCTATCTGCGTAGCAACCCGCTGATGAAGGAGCCTTTCACCCGCGAAGACGTCAAGCACCGTCTGGTCGGTCACTGGGGCACCACCCCGGGCCTGAACTTCCTCATCGGCCACATCAACCGTCTCATTGCTGATCACCAGCAGAACACTGTGATCATCATGGGCCCGGGCCACGGCGGCCCGGCTGGTACCGCTCAGTCCTACCTGGACGGCACCTACACCGAGTACTTCCCGAACATCACCAAGGATGAGGCTGGCCTGCAGAAGTTCTTCCGCCAGTTCTCCTACCCGGGTGGCATCCCGTCCCACTACGCTCCGGAGACCCCGGGCTCCATCCACGAAGGCGGCGAGCTGGGTTACGCCCTGTCCCACGCCTACGGCGCTGTGATGAACAACCCGAGCCTGTTCGTCCCGGCCATCGTCGGCGACGGTGAAGCTGAGACCGGCCCGCTGGCCACCGGCTGGCAGTCCAACAAGCTCATCAACCCGCGCACCGACGGTATCGTGCTGCCGATCCTGCACCTCAACGGCTACAAGATCGCCAACCCGACCATCCTGTCCCGCATCTCCGACGAAGAGCTCCACGAGTTCTTCCACGGCATGGGCTATGAGCCGTACGAGTTCGTCGCTGGCTTCGACAACGAGGATCACCTGTCGATCCACCGTCGTTTCGCCGAGCTGTTCGAGACCGTCTTCGACGAGATCTGCGACATCAAGGCCGCCGCTCAGACCGACGACATGACTCGTCCGTTCTACCCGATGATCATCTTCCGTACCCCGAAGGGCTGGACCTGCCCGAAGTTCATCGACGGCAAGAAGACCGAGGGCTCCTGGCGTTCCCACCAGGTGCCGCTGGCTTCCGCCCGCGATACCGAGGCCCACTTCGAGGTCCTCAAGAACTGGCTCGAGTCCTACAAGCCGGAAGAGCTGTTCGACGAGAACGGCGCCGTGAAGCCGGAAGTCACCGCCTTCATGCCGACCGGCGAACTGCGCATCGGTGAGAACCCGAACGCCAACGGTGGCCGCATCCGCGAAGAGCTGAAGCTGCCGAAGCTGGAAGACTACGAGGTCAAGGAAGTCGCCGAGTACGGCCACGGCTGGGGCCAGCTCGAGGCCACCCGTCGTCTGGGCGTCTACACCCGCGACATCATCAAGAACAACCCGGACTCCTTCCGTATCTTCGGACCGGATGAGACCGCTTCCAACCGTCTGCAGGCCGCTTACGACGTCACCAACAAGCAGTGGGACGCCGGCTACCTGTCCGCTCAGGTCGACGAGCACATGGCTGTCACCGGCCAGGTCACCGAGCAGCTTTCCGAGCACCAGATGGAAGGCTTCCTCGAGGGCTACCTGCTGACCGGCCGTCACGGCATCTGGAGCTCCTATGAGTCCTTCGTGCACGTGATCGACTCCATGCTGAACCAGCACGCCAAGTGGCTCGAGGCTACCGTCCGCGAGATTCCGTGGCGCAAGCCGATCTCCTCCATGAACCTGCTCGTCTCCTCCCACGTGTGGCGTCAGGATCACAACGGCTTCTCCCACCAGGATCCGGGTGTCACCTCCGTCCTGCTGAACAAGTGCTTCAACAACGATCACGTGATCGGCATCTACTTCCCGGTGGATTCCAACATGCTGCTCGCTGTGGCTGAGAAGTGCTACAAGTCCACCAACAAGATCAACGCCATCATCGCCGGCAAGCAGCCGGCCGCCACCTGGCTGACCCTGGACGAAGCTCGCGCCGAGCTCGAGAAGGGTGCTGCCGAGTGGAAGTGGGCTTCCAACGTGAAGTCCAACGATGAGGCTCAGATCGTGCTCGCCGCCACCGGTGATGTTCCGACTCAGGAAATCATGGCCGCTGCCGACAAGCTGGACGCCATGGGCATCAAGTTCAAGGTCGTCAACGTGGTTGACCTGGTCAAGCTGCAGTCCGCCAAGGAGAACAACGAGGCCCTCTCCGATGAGGAGTTCGCTGAGCTGTTCACCGAGGACAAGCCGGTCCTGTTCGCTTACCACTCCTATGCCCGCGATGTGCGTGGTCTGATCTACGATCGCCCGAACCACGACAACTTCAACGTTCACGGCTACGAGGAGCAGGGCTCCACCACCACCCCGTACGACATGGTTCGCGTGAACAACATCGATCGCTACGAGCTCCAGGCTGAAGCTCTGCGCATGATTGACGCTGACAAGTACGCCGACAAGATCAACGAGCTCGAGGCCTTCCGTCAGGAAGCCTTCCAGTTCGCTGTCGACAACGGCTACGATCACCCGGATTACACCGACTGGGTCTACTCCGGTGTCAACACCAACAAGCAGGGTGCTATCTCCGCTACCGCCGCAACCGCTGGCGATAACGAGTGA

Xfpk is a generalist phosphoketolase capable of generating intermediates of the pentose phosphate pathway (PPP). The production of these intermediates prevents carbon loss that normally occurs during the oxidative decarboxylation of glucose-6-phosphate in the PPP, where CO₂ is released. However, XfpK activity also leads to the formation of acetyl phosphate, which must be properly managed to ensure its reincorporation into central metabolism. Moreover, this alternative route does not generate NADPH, resulting in the absence of reducing power typically supplied by the PPP [322].

`Synonyms:`	fpk, xfspK
`Gene size:`
`Protein size:`
`Reactions`	R677 , R00864 and R2193
`Compounds affected`	L-tyrosine , L-phenylalanine and L-tryptophan

Databases

`EraGene:`	1149933