idi

Escherichia coli

Sequence

                ATGCAAACGGAACACGTCATTTTATTGAATGCACAGGGAGTTCCCACGGGTACGCTGGAAAAGTATGCCGCACACACGGCAGACACCCGCTTACATCTCGCGTTCTCCAGTTGGCTGTTTAATGCCAAAGGACAATTATTAGTTACCCGCCGCGCACTGAGCAAAAAAGCATGGCCTGGCGTGTGGACTAACTCGGTTTGTGGGCACCCACAACTGGGAGAAAGCAACGAAGACGCAGTGATCCGCCGTTGCCGTTATGAGCTTGGCGTGGAAATTACGCCTCCTGAATCTATCTATCCTGACTTTCGCTACCGCGCCACCGATCCGAGTGGCATTGTGGAAAATGAAGTGTGTCCGGTATTTGCCGCACGCACCACTAGTGCGTTACAGATCAATGATGATGAAGTGATGGATTATCAATGGTGTGATTTAGCAGATGTATTACACGGTATTGATGCCACGCCGTGGGCGTTCAGTCCGTGGATGGTGATGCAGGCGACAAATCGCGAAGCCAGAAAACGATTATCTGCATTTACCCAGCTTAAATAA

idi encodes isopentenyl diphosphate isomerase from Escherichia coli, which catalyzes the reversible interconversion of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [354,347]. This reaction exhibits an equilibrium constant of approximately three, favoring conversion toward DMAPP [354]. Consequently, overexpression of idi has been widely employed in engineered strains to optimize the IPP/DMAPP ratio, thereby enhancing the supply of C5 isoprenoid precursors for downstream terpenoid biosynthesis, including geraniol and sesquiterpene production [354,347].

`Gene size:`
`Protein size:`
`Reactions`	R123
`Compounds affected`	geraniol , (2E,6E)-farnesol , valerena-4,7(11)-diene , (4S)-limonene , geranate , (E,E)-α-farnesene , all-trans-lycopene and (-)-patchoulol

Databases

`EraGene:`	2111386
`KEGG:`	eco:b2889