cyoA

Escherichia coli

Sequence

                atgAGACTCAGGAAATACAATAAAAGTTTGGGATGGTTGTCATTATTTGCAGGCACTGTATTGCTCAGTGGCTGTAATTCTGCGCTGTTAGATCCCAAAGGACAGATTGGTCTGGAGCAACGTTCACTGATACTGACGGCATTTGGCCTGATGTTGATTGTCGTTATTCCCGCAATCTTGATGGCTGTTGGTTTCGCCTGGAAGTACCGTGCGAGCAATAAAGATGCTAAGTACAGCCCGAACTGGTCACACTCCAATAAAGTGGAAGCTGTGGTCTGGACGGTACCTATCTTAATCATCATCTTCCTTGCAGTACTGACCTGGAAAACCACTCACGCTCTTGAGCCTAGCAAGCCGCTGGCACACGACGAGAAGCCCATTACCATCGAAGTGGTTTCCATGGACTGGAAATGGTTCTTCATCTACCCGGAACAGGGCATTGCTACCGTGAATGAAATCGCTTTCCCGGCGAACACTCCGGTGTACTTCAAAGTGACCTCCAACTCCGTGATGAACTCCTTCTTCATTCCGCGTCTGGGTAGCCAGATTTATGCCATGGCCGGTATGCAGACTCGCCTGCATCTGATCGCCAACGAACCCGGCACTTATGACGGTATCTCCGCCAGCTACAGCGGCCCGGGCTTCTCAGGCATGAAGTTCAAAGCTATTGCAACACCGGATCGCGCCGCATTCGACCAGTGGGTCGCAAAAGCGAAGCAGTCGCCGAACACCATGTCTGACATGGCTGCGTTCGAAAAACTGGCCGCGCCTAGCGAATACAACCAGGTGGAATATTTCTCCAACGTGAAACCAGACTTGTTTGCCGATGTAATTAACAAGTTTATGGCTCACGGTAAGAGCATGGACATGACCCAGCCAGAAGGTGAGCACAGCGCACACGAAGGTATGGAAGGCATGGACATGAGCCACGCGGAATCCGCCCATtaa

The cyoABCD genes encode the Cyo terminal oxidase complex in Escherichia coli, which transfers electrons from quinols to molecular oxygen while generating a proton motive force, with a stoichiometry of two protons translocated per electron transferred (H⁺/e⁻ = 2). Deletion of cyoABCD significantly improves the aerobic production of 2,3-butanediol and isobutanol by attenuating electron transport chain activity and increasing the intracellular NADH/NAD⁺ ratio [356].

`Gene size:`
`Protein size:`
`Reactions`	R00899
`Compounds affected`	L-histidine , isobutanol and (R,R)-2,3-butanediol

Databases

`EraGene:`	2197883
`KEGG:`	eco:b0432