an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(S)-dihydroorotate

2-amino-3-carboxymuconate-6-semialdehyde

preuroporphyrinogen

anthranilate

(R)-mevalonate diphosphate

shikimate

3-dehydroshikimate

3-dehydroquinate

thiamine diphosphate

7-carboxy-7-deazaguanine

(indol-3 yl)acetyl-CoA

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine phosphate

N-(5-phosphoribosyl)-anthranilate

porphobilinogen

S-methyl-5'-thioadenosine

S-Inosyl-L-homocysteine

tetrahydrogeranylgeranyl diphosphate

dihydrogeranylgeranyl diphosphate

(R)-4'-phosphopantothenoyl-L-cysteine

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

4'-phosphopantetheine

(indol-3-yl)pyruvate

prephenate

urea

hydrogenobyrinate a,c-diamide

hydrogenobyrinate

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

O-acetyl-L-serine

S-adenosyl 3-(methylsulfanyl)propylamine

acetyl phosphate

histidinal

histidinol

β-D-ribosylnicotinate

L-canavanine

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

N-acetyl-L-glutamate 5-semialdehyde

imidazole acetol-phosphate

L-histidinol phosphate

2-phosphoglycolate

glycolate

oxalate

coenzyme B

CoB-CoM heterodisulfide

phosphoenolpyruvate

3-phosphooxypyruvate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

(2S)-lactyl-2-diphospho-5'-guanosine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

carbon monoxide

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

hexulose 6-phosphate

propan-2-ol

nicotinate adenine dinucleotide

(R)-mevalonate

(R)-5-phosphomevalonate

isopentenyl diphosphate

prenyl diphosphate

DNA without lesion

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

D-erythro-imidazole-glycerol-phosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(D-ribitylamino)uracil

2-dehydropantoate

L-β-lysine

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

α-D-ribose 1,5-bisphosphate

carbonic acid

methanophenazine

dihydromethanophenazine

oxalosuccinate

N⁵-carboxyaminoimidazole ribonucleotide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

coproporphyrinogen III

hydrogen peroxide

N-acetylglutamyl-phosphate

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

H₂

β-nicotinate D-ribonucleotide

quinolinate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

L-arginino-succinate

O-ureido-L-homoserine

canavaninosuccinate

glycerone phosphate

oxaloacetate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

carbamoyl phosphate

carboxyphosphate

(2S)-2-isopropylmalate

2-isopropylmaleate

H₂O

(2R,3S)-3-isopropylmalate

orotidine 5'-phosphate

3-methyl-2-oxobutanoate

CO₂

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

ammonia

enol-phenylpyruvate

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

S-ribosyl-L-homocysteine

autoinducer 2

DNA with lesion

L-homocysteine

phenylacetate

N₂

cobalt-factor III

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

cobalt-precorrin-3

cobalt-precorrin-4

cobalt-precorrin-5A

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-2

cobalt-sirohydrochlorin

protoporphyrinogen IX

uroporphyrinogen-III

uroporphyrinogen-I

oxygen

hydrogen sulfide

2-iminosuccinate

2-chloroacetate

β-D-mannosyl-(C55 ω-saturated dolichyl phosphate)

sn-glycerol 1-phosphate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

ω-saturated C55 dolichol phosphate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(S)-citramalate

preQ₀

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

ammonium

H⁺

Co²⁺

Zn²⁺

Cd²⁺

Mo²⁺

hydrogencarbonate

nitrate

phosphate

triphosphate

diphosphate

chloride

pristanate

glycine betaine

agmatine

putrescine

dehydrospermidine

spermidine

tyramine

S-(hydroxymethyl)glutathione

glutathione

methanethiol

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

L-cysteate

3-sulfopyruvate

coenzyme M

(R)-S-lactoylglutathione

(S)-3-hydroxy-3-methylglutaryl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

3'-dephospho-CoA

phenylacetyl-CoA

malonyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

2-methylacetoacetyl-CoA

succinyl-CoA

acetyl-CoA

isobutanoyl-CoA

phytenoyl-CoA

oleoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

7-hydroxylauroyl-CoA

18-hydroxystearoyl-CoA

16-hydroxypalmitoyl-CoA

18-hydroxyoleoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

octanoyl-CoA

lauroyl-CoA

decanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

methane

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

riboflavin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

FAD

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

caldariellaquinone

caldariellaquinol

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

XMP

GMP

5'-deoxyadenosine

dADP

dATP

IDP

ITP

dIDP

dITP

dGDP

dGTP

AMP

ATP

ADP

GTP

IMP

adenylo-succinate

GDP

P¹,P⁴-bis(5'-adenosyl) tetraphosphate

xanthosine

guanosine

inosine

adenosine

uridine

cytidine

2'-deoxycytidine

2'-deoxyuridine

thymidine

dTTP

dCTP

dUTP

UTP

CTP

dUMP

dTMP

dCMP

CMP

UMP

dTDP

dUDP

dCDP

CDP

UDP

β-nicotinamide D-ribonucleotide

GDP-α-D-mannose

GDP-4-dehydro-α-D-rhamnose

uracil

thymine

adenine

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-glucuronate

UDP-α-D-galactose

methyl-CoM

coenzyme A

oxidized coenzyme F₄₂₀-0

MoO₂-molybdopterin cofactor

guanylyl molybdenum cofactor

precorrin-8x

precorrin-1

precorrin-2

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

7,8-dihydroneopterin 3'-triphosphate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

6-carboxy-5,6,7,8-tetrahydropterin

orotate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

diacetyl

acetone

methylglyoxal

formaldehyde

acetaldehyde

D-glyceraldehyde

methanol

ethanol

1-(β-D ribofuranosyl)nicotinamide

keto-D-fructose

β-D-fructofuranose

D-ribulose-1,5-bisphosphate

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

18-hydroxystearate

16-hydroxypalmitate

18-hydroxyoleate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

saturated archaetidylserine

saturated archaetidylethanolamine

unsaturated archaetidylserine

unsaturated archaetidylethanolamine

phytyl diphosphate

geranylgeranyl diphosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

chorismate

succinate

fumarate

L-aspartate

(S)-malate

α,ω-9Z-octadecenedioate

D-threo-isocitrate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

pyruvate

4-(methylsulfanyl)-2-oxobutanoate

2-oxobutanoate

2-oxoglutarate

acetate

formate

(S)-lactate

(R)-lactate

octanoate

7-hydroxylaurate

laurate

decanoate

(15Z)-tetracosenoate

oleate

α-linolenate

linoleate

stearate

palmitate

phytenate

(R)-pantoate

carbamate

L-serine

L-threonine

glycine

L-tyrosine

L-glutamine

L-arginine

L-histidine

L-lysine

L-glutamate

L-leucine

L-isoleucine

L-valine

L-methionine

L-tryptophan

L-phenylalanine

(R)-β-lysine

L,L-diaminopimelate

L-aspartyl-4-phosphate

L-ornithine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

3-phospho-L-serine

N-acetyl-L-glutamate

O-acetyl-L-homoserine

L-citrulline

L-canaline

O-phospho-L-homoserine

L-homoserine

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

meso-diaminopimelate