Titer in Flask for β-alanine

Strain Production
mg/L
1000
2000
3000
4000
5000
6000
7000
E. coli BW25113/F'
E. coli W3110/pTac15kPE
E. coli CWF4N/pTac15kPC
E. coli XB00
E. coli W3110/pTac15kPC
E. coli CWF4NA/pTac15kPAC
E. coli XB01
E. coli CWF4NA/pTac15kPC
E. coli XD11-2
E. coli XB11
E. coli XB02
E. coli XD11-3
E. coli XD11-1
E. coli CWF4NA/pTac15kPC/pSynPPC1
E. coli CWF4NA/pTac15kPRA/pSynPPC1
E. coli XBG11
E. coli CWF4NA/pTac15kPTA/pSynPPC1
E. coli CWF4NA/pTac15kPTA/pSynPPC7
E. coli XBR11
E. coli XBR27
E. coli XBR21
E. coli XBR22

Titer in Fed-Batch for β-alanine

Strain Production
mg/L
8000.0
16000.0
24000.0
32000.0
40000.0
E. coli CWF4NA/pTac15kPTA/pSynPPC7
E. coli CWF4NA2/pTac15kPTA/pSynPPC7
E. coli XBR22
E. coli XBR41

Substrate yield in Flask for β-alanine

Strain Production
g/g of sustrate
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
E. coli CWF4NA/pTac15kPTA/pSynPPC7
E. coli XBR11
E. coli XBR21
E. coli XBR22

Substrate yield in Fed-Batch for β-alanine

Strain Production
g/g of sustrate
0.1
0.2
0.3
0.4
0.5
E. coli CWF4NA2/pTac15kPTA/pSynPPC7
E. coli XBR41

Volumetric productivity in Fed-Batch for β-alanine

Strain Production
mg/L/h
100
200
300
400
500
600
700
800
900
E. coli CWF4NA/pTac15kPTA/pSynPPC7
E. coli CWF4NA2/pTac15kPTA/pSynPPC7