Escherichia coli T14

Ancestors

All strains

Escherichia coli K12

Escherichia coli W1485

Escherichia coli W2637

Escherichia coli W3110

Escherichia coli T8

Escherichia coli T9

Escherichia coli T10

Escherichia coli T11

Escherichia coli T13

Escherichia coli T14

Genotype with respect to parental

ΔpheA ΔtyrA

Genotype with respect to wild type

F⁺ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | ΔlacI, tyrR::Ptrc-aroGS180F, trpR::Ptrc-serAH344A,N364A, trpE::Ptrc-trpES40F, ΔpykF, tktA::Ptrc-tktA, ΔptsH, yjiV::PJ23105-UTRWP1-galP, ylbE::PJ23114-UTRMK3-glk, PrpsT p1-ppc, Prrnc p1-gltA | P_trc-aroEK | mbhA::P_trc-BS.glnA^L159I,E304A | yeeP::P_serB-serB, P_serC-serC | ΔTnaB | ΔpheA ΔtyrA

Bars (|) indicate differences between strains.

Modifications

Gene	Organism	Modification
pheA	Escherichia coli	Silencing
tyrA	Escherichia coli	Silencing

Production

Metabolites	Heterologous	Production type	Production	Biomass	Carbon source	Time	Scale	Ref.
L-tryptophan		Titer	12.29 g/L		Glucose		Flask	[ 183 ]

* Inferred from plots using RetroPlot.

References

Liu S, Wang BB, Xu JZ, Zhang WG. Engineering of Shikimate Pathway and Terminal Branch for Efficient Production of L-Tryptophan in Escherichia coli. Int J Mol Sci. 2023 Jul 24;24(14):11866.