an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

α-D-galacturonate 1-phosphate

L-xylo-hex-3-ulono-1,4-lactone

L-gulono-1,4-lactone

L-arginino-succinate

4-amino-2-methyl-5-pyrimidinemethanol

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

carbon monoxide

(R)-4'-phosphopantothenate

2-(α-hydroxyethyl)thiamine diphosphate

oxalosuccinate

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

cyclohexane-1-carbonyl-CoA

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

3-methyl-2-oxobutanoate

creatinine

31-O-desmethylFK-506

FK-506

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

(S)-2-amino-6-oxohexanoate

S-adenosyl 3-(methylsulfanyl)propylamine

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

(R)-4'-phosphopantothenoyl-L-cysteine

S-methyl-5'-thioadenosine

5-deoxy-α-ribose 1-phosphate

2-C-methyl-D-erythritol 4-phosphate

γ-L-glutamyl 5-phosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

(L-threonylcarbamoyl)adenylate

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

(S)-dihydroorotate

ethanolamine

H₂

2-oleoylglycerol

3-phosphonopyruvate

orotidine 5'-phosphate

4,8,12-trimethyltridecanoyl-CoA

3-oxopristanoyl-CoA

itaconate

urea

urea-1-carboxylate

salicyl alcohol

methylsalicylate

xanthine

nigerose

pseudouridine 5'-phosphate

coproporphyrinogen III

glycolate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

2-dehydropantoate

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

3'-phosphoadenylyl-sulfate

β-nicotinate D-ribonucleotide

quinolinate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

glycerone phosphate

isopentenyl diphosphate

prenyl diphosphate

5-amino-6-(D-ribitylamino)uracil

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

4'-phosphopantetheine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

coenzyme B

methanophenazine

CoB-CoM heterodisulfide

dihydromethanophenazine

hydrogen peroxide

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

(lipoyl)adenylate

carbamoyl phosphate

nicotinate adenine dinucleotide

5-carboxymethyl-2-hydroxymuconate

phosphoenolpyruvate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

(R)-5-phosphomevalonate

3-phosphooxypyruvate

thiamine phosphate

thiamine diphosphate

(R)-mevalonate

CO₂

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

oxaloacetate

citrate

4-imidazolone-5-propanoate

urocanate

α-D-glucosamine 1-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

H₂O

2-carboxy-L-threo-pentonate

2-carboxy-L-xylonolactone

2,3-dioxo-L-gulonate

dehydroascorbate (bicyclic form)

ammonia

1-piperideine 6-carboxylate

aminoacetone

L-dehydro-ascorbate

dimethyl sulfide

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

coenzyme M

sulfate

molybdate

hydrogencarbonate

sulfite

selenate

hydrogensulfite

phosphate

triphosphate

diphosphate

chloride

Fe³⁺

H⁺

ammonium

Co²⁺

Fe²⁺

trimethyl sulfonium

agmatine

putrescine

dehydrospermidine

spermidine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2-iminopropanoate

2-aminoprop-2-enoate

glycerophosphoglycerol

glycerophosphoserine

sn-glycero-3-phosphoethanolamine

2-chloroacetate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

methyl (indol-3-yl)acetate

(indol-3-yl)acetate

all-trans-retinyl palmitate

L-galactono-1,4-lactone

glutaryl-CoA

isobutanoyl-CoA

2-methylacetoacetyl-CoA

itaconyl-CoA

3'-dephospho-CoA

succinyl-CoA

(E)-glutaconyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

acetyl-CoA

(S)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

crotonyl-CoA

(S)-3-hydroxybutanoyl-CoA

propanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

molybdopterin

(R)-lipoate

coenzyme A

MoO₂-molybdopterin cofactor

guanylyl molybdenum cofactor

7,8-dihydrofolate monoglutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

L-ascorbate

riboflavin

all-trans-retinol

menadione

adenine

guanine

2'-deoxyguanosine

2'-deoxyadenosine

2'-deoxyinosine

inosine

adenosine

hypoxanthine

dAMP

dGMP

dIMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

XMP

GMP

IMP

AMP

XTP

ITP

GTP

ATP

orotate

uracil

dUMP

dTMP

UTP

dUDP

dUTP

dTDP

dTTP

dCTP

CTP

dCMP

dCDP

UDP

CDP

cytidine

uridine

thymidine

2'-deoxycytidine

2'-deoxyuridine

thymine

UMP

CMP

UDP-α-D-galacturonate

UDP-α-D-galactofuranose

UDP-α-D-galactose

UDP-α-D-glucose

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-glucosamine

dTDP-β-L-rhamnose

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

dTDP-4-dehydro-β-L-rhamnose

dTDP-α-D-glucose

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

preQ₁

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-5A

precorrin-1

precorrin-2

sirohydrochlorin

cobyrinate

cob(I)alamin

adenosylcobalamin

7,8-dihydrolumazine

6,7-dimethyl-8-(1-D-ribityl)lumazine

molybdopterin adenine dinucleotide

cyclic pyranopterin phosphate

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropteroate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

preQ₀

(indole-3-yl)acetonitrile

salicyl-6-hydroxy-2-cyclohexene-on-oyl

6-hydroxy-2-cyclohexen-one-carboxylate

salicylate

benzoate

4-aminobenzoate

menadiol

palmitate

(R)-pantoate

acetate

aldehydo-D-galacturonate

aldehydo-D-glucuronate

glyoxylate

2-oxobutanoate

pyruvate

2-oxoglutarate

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

L-cysteine

L-tyrosine

L-threonine

L-serine

glycine

L-asparagine

L-glutamine

L-lysine

N^ω-hydroxy-L-arginine

L-arginine

L-histidine

L-aspartate

L-glutamate

D-aspartate

D-alanine

L-aspartyl-4-phosphate

L-2-amino-3-oxobutanoate

N-formimino-L-glutamate

N-carbamoyl-L-aspartate

3-phospho-L-serine

L-citrulline

L-homoserine

O-phospho-L-homoserine

L-ornithine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-homocysteine

L-methionine

L-leucine

L-alanine

creatine

succinate

fumarate

(S)-malate

cis-aconitate

(2R)-homocitrate

(1R,2S)-homoisocitrate

cis-homoaconitate

D-threo-isocitrate

(R)-lactate

(S)-lactate

(R)-glycerate

propanoate

formate

β-D-glucopyranose

α-D-glucopyranose

α-D-galactopyranose

acetaldehyde

(S)-lactaldehyde

myo-inositol

1D-myo-inositol 2-monophosphate

1D-myo-inositol 1-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 5-monophosphate

1D-myo-inositol 4-monophosphate

1D-myo-inositol 3-monophosphate

methanol

glycerol

1-oleoyl-sn-glycerol 3-phosphate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

(2E,6E)-farnesyl diphosphate

phytyl diphosphate

3-octaprenyl-4-hydroxybenzoate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

sucrose

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

D-ribulose-1,5-bisphosphate

sucrose 6^F-phosphate

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

α-D-galactose 1-phosphate

β-D-glucopyranose 1-phosphate

aldehydo-L-galactonate

L-gulonate

cyclic-AMP

5'-deoxyadenosine

adenylo-succinate

reduced β-nicotinamide D-ribonucleotide

β-nicotinamide D-ribonucleotide

2-iminosuccinate

hippurate

phosphonoacetaldehyde

cobalt-factor III

cobalt-sirohydrochlorin

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

cob(I)inamide

adenosylcobinamide

uroporphyrinogen-III

protoporphyrinogen IX

hydrogen sulfide

oxygen

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol

nitric oxide

monodehydroascorbate radical