an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

3-methyl-2-oxobutanoate

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

(S)-3-methyl-2-oxopentanoate

1-deoxy-L-glycero-tetrulose 4-phosphate

H₂O

L-canavanine

2-dehydro-3-deoxy-D-gluconate 6-phosphate

(R)-mevalonate diphosphate

aminoacetone

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

4'-phosphopantetheine

(2S)-lactyl-2-diphospho-5'-guanosine

2-dehydro-3-deoxy-D-galactonate 6-phosphate

1,4-dihydroxy-2-naphthoyl-CoA

N-methylhydantoin

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

CO₂

urea

canavaninosuccinate

O-ureido-L-homoserine

L-arginino-succinate

glycerone phosphate

imidazole acetol-phosphate

D-erythro-imidazole-glycerol-phosphate

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

(2S)-2-isopropylmalate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

(R)-2,3-dihydroxy-3-methylpentanoate

prephenate

acetoacetate

4-fumaryl-acetoacetate

carbonic acid

2-dehydro-3-deoxy-D-gluconate

(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate

(R)-mandelate

(S)-mandelate

2-succinylbenzoate

3-phosphooxypyruvate

hydrogen peroxide

quinolinate

β-nicotinate D-ribonucleotide

orotidine 5'-phosphate

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

isochorismate

prenyl diphosphate

(R)-4'-phosphopantothenoyl-L-cysteine

thiamine phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

formate

(S)-4-amino-5-oxopentanoate

isopentenyl diphosphate

thiamine diphosphate

choline

choline sulfate

glutathione disulfide

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

ammonia

4-amino-2-methyl-5-pyrimidinemethanol

pyrithiamine

oxythiamine

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

citrate

oxaloacetate

nicotinate adenine dinucleotide

bisorganyltrisulfane

1,4-dihydroxy-2-naphthoate

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

tartronate semialdehyde

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

3-amino-1-hydroxyacetone 1-phosphate

4-phosphooxy-L-threonine

2-phosphoglycolate

2-dehydro-3-deoxy-D-galactonate

glycolate

2-dehydropantoate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

α-D-glucosamine 1-phosphate

carbamoyl phosphate

histidinol

histidinal

oxalate

5-amino-6-(D-ribitylamino)uracil

(4Z)-2-oxohept-4-enedioate

4-amino-4-deoxychorismate

N-(5-phosphoribosyl)-anthranilate

anthranilate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

coproporphyrinogen III

5-methylcytosine

fecosterol

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

3-oxopropanoate

succinate semialdehyde

(4S)-4-hydroxy-2-oxoheptanedioate

isopentenyl phosphate

arsenite

3-dehydroquinate

3-deoxy-D-arabino-heptulosonate 7-phosphate

(indol-3-yl)acetamide

phosphoenolpyruvate

(R)-mevalonate

(R)-5-phosphomevalonate

S-Inosyl-L-homocysteine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

DNA without lesion

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

(R)-4'-phosphopantothenate

(R)-4-phosphopantoate

4-hydroxy-2-nonenal

(S)-dihydroorotate

methylsalicylate

salicyl alcohol

creatinine

carboxyphosphate

(2R,3S)-3-methylmalate

citraconate

N-succinyl-2-amino-6-ketopimelate

(S)-2,3,4,5-tetrahydrodipicolinate

N-succinyl-L,L-2,6-diaminopimelate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

4-methyl-3-oxoadipate

4-methyl-3-oxoadipate-enol-lactone

(4,5-dihydro-5-oxofuran-2-yl)-acetate

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

dihydroxyacetone

shikimate 3-phosphate

shikimate

5-enolpyruvoyl-shikimate 3-phosphate

5-phospho-β-D-ribosylamine

L-histidinol phosphate

N¹-(5-phospho-β-D-ribosyl)glycinamide

porphobilinogen

5-aminolevulinate

preuroporphyrinogen

3-dehydroshikimate

autoinducer 2

S-ribosyl-L-homocysteine

D-glyceraldehyde

methylglyoxal

benzaldehyde

acetaldehyde

formaldehyde

3-methyl-6-methoxy-2-octaprenyl-1,4-benzoquinone

6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone

caldariellaquinone

diacetyl

4-hydroxybenzoate

6-hydroxy-2-cyclohexen-one-carboxylate

salicyl-6-hydroxy-2-cyclohexene-on-oyl

salicylate

4-aminobenzoate

benzoate

2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinol

2,3-dimethyl-6-phytyl-1,4-benzoquinol

2-methyl-6-phytyl-1,4-benzoquinol

caldariellaquinol

demethylmenaquinol-9

demethylmenaquinol-11

demethylmenaquinol-13

demethylmenaquinol-12

demethylmenaquinol-7

demethylmenaquinol-6

demethylmenaquinol-10

demethylmenaquinol-8

menaquinol-9

menaquinol-10

menaquinol-11

menaquinol-13

menaquinol-12

menaquinol-7

menaquinol-6

menaquinol-8

plastoquinol-9

tyramine

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

geranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

all-trans-heptaprenyl diphosphate

all-trans-octaprenyl diphosphate

(2E,6E)-farnesyl diphosphate

geranylgeranyl diphosphate

all-trans-retinyl palmitate

all-trans-retinol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

18-hydroxyoleate

16-hydroxypalmitate

18-hydroxystearate

carbamate

L-citrulline

L-aspartate

L-serine

L-proline

L-threonine

L-histidine

L-glutamate

L-arginine

L-tryptophan

L-glutamine

L-valine

L-leucine

L-isoleucine

glycine

L-phenylalanine

L-tyrosine

L-lysine

L-methionine

L-glutamate-5-semialdehyde

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

L-homocysteine

S-adenosyl-L-homocysteine

O-phospho-L-homoserine

L-canaline

L-ornithine

L-homoserine

L-allo-threonine

meso-diaminopimelate

L-aspartyl-4-phosphate

L-2-amino-3-oxobutanoate

O-acetyl-L-homoserine

N-acetyl-L-ornithine

N-acetyl-L-citrulline

N-acetyl-L-glutamate

sarcosine

N,N-dimethylglycine

N-carbamoyl-L-aspartate

3-phospho-L-serine

L,L-diaminopimelate

L-threo-3-phenylserine

N-carbamoylsarcosine

creatine

β-alanine

D-gluconate

D-mannonate

acetate

orotate

(R)-pantoate

(S)-1-pyrroline-5-carboxylate

pristanate

stearate

palmitate

octanoate

laurate

7-hydroxylaurate

decanoate

phytenate

(15Z)-tetracosenoate

oleate

linoleate

α-linolenate

(R)-lactate

(S)-lactate

(R)-glycerate

(R)-3-hydroxybutanoate

propanoate

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

pyruvate

glyoxylate

2-oxoglutarate

2-oxobutanoate

cis-2-methylaconitate

(2S,3S)-2-methylcitrate

cis-aconitate

D-threo-isocitrate

chorismate

α,ω-9Z-octadecenedioate

(4S)-4-hydroxy-2-oxoglutarate

fumarate

succinate

(R)-malate

3-oxoadipate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6-dihydroxy-6-(hydroxymethyl)-diketopiperazine

D-galactonate

dTDP-α-D-glucose

UDP-α-D-galactose

UDP-α-D-glucose

UDP-N-acetyl-α-D-glucosamine

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

α-D-glucopyranose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-fructose 1,6-bisphosphate

D-tagatofuranose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

β-D-fructofuranose

keto-L-sorbose

keto-D-fructose

N-acetyl-β-D-mannosamine

N-acetyl-β-neuraminate

glycerol

L-iditol

D-sorbitol

3,5-cyclohexadiene-1,2-diol-1-carboxylate

methanol

ethanol

adenine

XMP

AMP

IMP

GMP

ITP

ATP

GTP

ADP

GDP

IDP

dIDP

dGDP

dADP

dITP

dATP

dGTP

adenosine

tetrahydromethanopterin

7,8-dihydropteroate

5,10-methylene-tetrahydromethanopterin

7,8-dihydrofolate monoglutamate

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

reduced riboflavin

FMNH₂

FMN

FAD

riboflavin

6,7-dimethyl-8-(1-D-ribityl)lumazine

uracil

thymine

cytosine

UDP

formylaminopyrimidine

dTDP

CDP

dCDP

dUDP

5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone

aminomethylpyrimidine

CTP

UTP

dCMP

dTMP

dCTP

dUTP

dTTP

dUMP

CMP

UMP

cytidine

uridine

2'-deoxyuridine

thymidine

2'-deoxycytidine

5-fluorouracil

sirohydrochlorin

precorrin-2

precorrin-1

2-(2-methylpyridin-3-yl)ethanol

coenzyme A

oxidized coenzyme F₄₂₀-0

5'-deoxyadenosine

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

β-nicotinamide D-ribonucleotide

NADP⁺

NAD⁺

NADPH

NADH

(S)-NADPHX

(R)-NADPHX

5-fluorocytosine

glycine betaine

(S)-NADHX

(R)-NADHX

thiamine

nicotinate

(indol-3-yl)acetate

methyl (indol-3-yl)acetate

24-methylenecycloartanol

cycloartenol

zymosterol

(S)-3-hydroxy-3-methylglutaryl-CoA

3'-dephospho-CoA

acetyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

(E)-glutaconyl-CoA

malonyl-CoA

succinyl-CoA

oleoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

acetoacetyl-CoA

16-hydroxypalmitoyl-CoA

palmitoyl-CoA

stearoyl-CoA

18-hydroxyoleoyl-CoA

18-hydroxystearoyl-CoA

pristanoyl-CoA

decanoyl-CoA

7-hydroxylauroyl-CoA

octanoyl-CoA

lauroyl-CoA

propanoyl-CoA

(Z)-15-tetracosenoyl-CoA

phytenoyl-CoA

crotonyl-CoA

S-(hydroxymethyl)glutathione

glutathione

(R)-S-lactoylglutathione

L-cysteate

3-sulfopyruvate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

methanethiol

thiocyanate

S-sulfanylglutathione

agmatine

putrescine

spermidine

cadaverine

(2Z)-2-aminobut-2-enoate

superoxide

hydrogencarbonate

hydrogensulfite

nitrite

thiosulfate

sulfite

selenate

sulfate

chloride

phosphonate

phosphate

diphosphate

Fe³⁺

Fe²⁺

Mo²⁺

Hg²⁺

Pb²⁺

Cd²⁺

Zn²⁺

H⁺

ammonium

2,4-dinitrophenyl-S-glutathione

1-chloro-2,4-dinitrobenzene

(R)-4-hydroxymandelate

(S)-4-hydroxymandelate

(S)-methylmalonate-semialdehyde

(R)-citramalate

(2R)-2,3-dihydroxy-3-methylbutanoate

(2S)-2-phospholactate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

Hg⁰

hydrogen sulfide

oxygen

uroporphyrinogen-III

coproporphyrinogen I

uroporphyrinogen-I

protoporphyrinogen IX

protoporphyrin IX

siroheme

DNA with lesion

2-iminosuccinate

2-iminobutanoate

(glutathion-S-yl)-4-hydroxy-2-nonenal

hydrogen cyanide