an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

carboxyphosphate

carbamoyl phosphate

H₂O

CO₂

oxaloacetate

H₂

L-histidinol phosphate

imidazole acetol-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

S-methyl-5'-thioadenosine

5-deoxy-α-ribose 1-phosphate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

(2S)-2-isopropylmalate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

quinolinate

β-nicotinate D-ribonucleotide

glycerone phosphate

3-methyl-2-oxobutanoate

canavaninosuccinate

O-ureido-L-homoserine

L-arginino-succinate

2-C-methyl-D-erythritol 4-phosphate

N-acetylglutamyl-phosphate

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

3-dehydroquinate

3-deoxy-D-arabino-heptulosonate 7-phosphate

5-amino-6-(D-ribitylamino)uracil

orotidine 5'-phosphate

5-phospho-β-D-ribosylamine

(S)-3-methyl-2-oxopentanoate

(R)-2,3-dihydroxy-3-methylpentanoate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

Coα-[α-(5-hydroxybenzimidazolyl)]-Coβ-methylcobamide

thiamine phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

7-carboxy-7-deazaguanine

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

prenyl diphosphate

4-prenylphlorisobutyrophenone

isopentenyl diphosphate

glycolate

2-phosphoglycolate

carbon monoxide

formate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

coproporphyrinogen III

5-(methylsulfanyl)-ribulose 1-phosphate

dihydromethanophenazine

CoB-CoM heterodisulfide

methanophenazine

coenzyme B

4'-phosphopantetheine

phosphoenolpyruvate

(R)-5-phosphomevalonate

(R)-mevalonate

(S)-2,3,4,5-tetrahydrodipicolinate

(2S)-lactyl-2-diphospho-5'-guanosine

5-methylcytosine

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

O-acetyl-L-serine

hexulose 6-phosphate

L-selenocystathionine

D-erythro-imidazole-glycerol-phosphate

nicotinate adenine dinucleotide

4-methyl-2-oxopentanoate

carbonic acid

N¹-(5-phospho-β-D-ribosyl)glycinamide

anthranilate

N-(5-phosphoribosyl)-anthranilate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

hydrogen peroxide

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

porphobilinogen

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

7,8-didemethyl-8-hydroxy-5-deazariboflavin

(S)-dihydroorotate

oxalate

(R)-4'-phosphopantothenoyl-L-cysteine

(R)-4'-phosphopantothenate

prephenate

N-acetyl-L-glutamate 5-semialdehyde

α-D-ribose 1,5-bisphosphate

shikimate

3-dehydroshikimate

oxalosuccinate

2,5-didehydro-D-gluconate

2-keto-D-gluconate

histidinol

histidinal

hydrogenobyrinate

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

2-dehydropantoate

glutathione disulfide

DNA without lesion

N-ethylammeline

deethylsimazine

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

N⁵-carboxyaminoimidazole ribonucleotide

1-deoxy-L-glycero-tetrulose 4-phosphate

ManNAc-GlcNAc-PP-undecaprenol

CDP-glycerol

citrate

preuroporphyrinogen

L-canavanine

creatinine

hydrogenobyrinate a,c-diamide

3-phosphooxypyruvate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

2-(sulfomethyl)thiazolidine-4-carboxylate

sulfoethylcysteine

(R)-mevalonate diphosphate

autoinducer 2

S-ribosyl-L-homocysteine

(2S)-2-isopropyl-3-oxosuccinate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

ammonia

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

carbamate

L-α-amino-ε-keto-pimelate

L-citrulline

L-cysteine

L-glutamate

L-glutamine

L-tryptophan

L-serine

L-tyrosine

L-aspartate

L-phenylalanine

L-methionine

L-threonine

L-lysine

L-leucine

L-valine

L-isoleucine

glycine

L-histidine

L-arginine

L-ornithine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-homocysteine

L-aspartate 4-semialdehyde

L-homoserine

O-phospho-L-homoserine

L-canaline

meso-diaminopimelate

L-aspartyl-4-phosphate

seleno-L-homocysteine

O-acetyl-L-homoserine

N-acetyl-L-ornithine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

3-phospho-L-serine

L,L-diaminopimelate

L-cystathionine

D-glutamate

creatine

acetate

orotate

(R)-pantoate

5-chloro-5-deoxy-D-ribonate

pristanate

palmitate

stearate

decanoate

laurate

7-hydroxylaurate

octanoate

butanoate

18-hydroxyoleate

16-hydroxypalmitate

18-hydroxystearate

phytenate

(15Z)-tetracosenoate

oleate

linoleate

α-linolenate

(S)-lactate

(R)-glycerate

2-oxoglutarate

pyruvate

2-oxobutanoate

5-chloro-4-hydroxy-2-oxopentanoate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

D-threo-isocitrate

chorismate

α,ω-9Z-octadecenedioate

fumarate

succinate

(S)-malate

Gro-P-ManNAc-GlcNAc-PP-undecaprenol

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

phlorisovalerophenone

(2E,6E)-farnesyl diphosphate

trans,octacis-decaprenyl phosphate

geranyl diphosphate

4-prenylphlorisovalerophenone

deoxycohumulone

deoxyhumulone

di-trans,octa-cis-undecaprenyl phosphate

geranylgeranyl diphosphate

1,2-dibutyrin

tributyrin

unsaturated CDP-archaeol

saturated CDP-archaeol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

unsaturated archaetidylethanolamine

unsaturated archaetidylserine

saturated archaetidylethanolamine

saturated archaetidylserine

1-oleoyl-2-palmitoyl-phosphatidylglycerol

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

GDP-4-dehydro-α-D-rhamnose

GDP-α-D-mannose

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

dTDP-α-D-glucose

dTDP-4-dehydro-β-L-rhamnose

dTDP-β-L-rhamnose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-α-D-galactofuranose

UDP-α-D-galactose

UDP-α-D-glucuronate

UDP-α-D-glucose

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-mannosaminuronate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-ribitol 5-phosphate

α-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

β-D-glucose 6-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose 5-phosphate

β-D-ribose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

D-ribulose-1,5-bisphosphate

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

D-glyceraldehyde

α-D-ribofuranose

glycolaldehyde

1D-myo-inositol 3-monophosphate

ethanol

butan-1-ol

methanol

methylglyoxal

(S)-lactaldehyde

acetaldehyde

butan-1-al

formaldehyde

caldariellaquinone

diacetyl

caldariellaquinol

demethylmenaquinol-8

menaquinol-8

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

tyramine

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

adenine

AMP

IMP

GMP

XMP

ATP

GTP

ITP

ADP

GDP

IDP

dGDP

dADP

dIDP

dGTP

dATP

dITP

hypoxanthine

adenosine

inosine

xanthosine

tetrahydromethanopterin

6-carboxy-5,6,7,8-tetrahydropterin

molybdopterin

(7,8-dihydropterin-6-yl)methyl diphosphate

6-(hydroxymethyl)-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

molybdopterin adenine dinucleotide

7,8-dihydromonapterin

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-triphosphate

cyclic pyranopterin phosphate

5,10-methylene-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

reduced riboflavin

FMNH₂

riboflavin

FMN

FAD

6,7-dimethyl-8-(1-D-ribityl)lumazine

uracil

thymine

cytosine

dCDP

dCMP

UDP

CDP

CTP

dTTP

dUMP

dUTP

dCTP

UTP

dTDP

dTMP

dUDP

UMP

CMP

uridine

cytidine

2'-deoxyuridine

thymidine

2'-deoxycytidine

5-fluorouracil

Coα-[α-(5-hydroxybenzimidazolyl)]-cobamide

sirohydrochlorin

cobyrinate

precorrin-2

precorrin-1

cobalt-precorrin-6A

cobalt-precorrin-5B

cobalt-precorrin-5A

cobalt-precorrin-4

cobalt-precorrin-2

precorrin-8x

cobalt-precorrin-6B

cobalt-precorrin-8

cobalt-precorrin-7

cobalt-precorrin-3

coenzyme A

methyl-CoM

coenzyme M

oxidized coenzyme F₄₂₀-0

5'-deoxyadenosine

adenylo-succinate

cyclic-AMP

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

β-nicotinamide D-ribonucleotide

NADP⁺

NAD⁺

NADPH

NADH

5-fluorocytosine

glycine betaine

(S)-NADHX

(R)-NADHX

nicotinate

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

pyridoxamine 5'-phosphate

phenylacetate

(indol-3-yl)acetate

(25S)-3-oxocholest-4-en-26-oyl-CoA

(25S)-3-oxocholest-4-en-26-oate

cholate

glycocholate

methane

succinyl-CoA

isobutanoyl-CoA

acetyl-CoA

2-methylacetoacetyl-CoA

3'-dephospho-CoA

linoleoyl-CoA

α-linolenoyl-CoA

phenylacetyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

16-hydroxypalmitoyl-CoA

palmitoyl-CoA

stearoyl-CoA

18-hydroxyoleoyl-CoA

18-hydroxystearoyl-CoA

pristanoyl-CoA

decanoyl-CoA

lauroyl-CoA

7-hydroxylauroyl-CoA

octanoyl-CoA

propanoyl-CoA

(Z)-15-tetracosenoyl-CoA

phytenoyl-CoA

S-(hydroxymethyl)glutathione

glutathione

(R)-S-lactoylglutathione

(2R)-phospho-3-sulfolactate

3-sulfopyruvate

L-cysteate

sulfoacetaldehyde

(2R)-3-sulfolactate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

methanethiol

agmatine

spermidine

dehydrospermidine

2-aminoprop-2-enoate

2-iminopropanoate

nitrate

hydrogencarbonate

sulfite

molybdate

chloride

phosphate

diphosphate

triphosphate

Ni²⁺

Mo²⁺

Fe²⁺

Co²⁺

H⁺

ammonium

2-chloroacetate

preQ₀

(indole-3-yl)acetonitrile

(S)-citramalate

(2R)-2,3-dihydroxy-3-methylbutanoate

(2S)-2-phospholactate

ω-saturated C55 dolichol phosphate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 1-phosphate

β-D-mannosyl-(C55 ω-saturated dolichyl phosphate)

2-iminosuccinate

hydrogen sulfide

oxygen

uroporphyrinogen-III

protoporphyrinogen IX

uroporphyrinogen-I

siroheme

cobalt-sirohydrochlorin

cob(II)yrinate a,c-diamide

cob(II)yrinate c-monoamide

cobalt-factor III

N₂

ethylphosphate

DNA with lesion