an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

isopentenyl diphosphate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

γ-L-glutamyl 5-phosphate

orotidine 5'-phosphate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

adenosine 5'-phosphoselenate

glutathione disulfide

5-oxo-L-proline

quinolinate

H₂

5-amino-6-(D-ribitylamino)uracil

β-nicotinate D-ribonucleotide

β-D-ribosylnicotinate

adenosine 5'-phosphosulfate

3'-phosphoadenylyl-sulfate

oxaloacetate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

hydrogen selenide

(R)-2,3-dihydroxy-3-methylpentanoate

O-ureido-L-homoserine

canavaninosuccinate

L-arginino-succinate

N-acetyl-L,L-2,6-diaminopimelate

coenzyme B

methanophenazine

CoB-CoM heterodisulfide

dihydromethanophenazine

phosphoenolpyruvate

N-acetylglutamyl-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

N-Formyl-L-kynurenine

carbamoyl phosphate

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

3-dehydroquinate

3-dehydroshikimate

glycerone phosphate

O-acetyl-L-serine

3-methyl-2-oxobutanoate

4-methyl-2-oxopentanoate

(S)-3-methyl-2-oxopentanoate

CO₂

N-(5-phosphoribosyl)-anthranilate

anthranilate

thiamine phosphate

thiamine diphosphate

N-acetyl-L-glutamate 5-semialdehyde

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

2-phosphoglycolate

glycolate

4'-phosphopantetheine

(R)-1-aminopropan-2-ol

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

H₂O

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

2-carboxy-L-threo-pentonate

2-carboxy-L-xylonolactone

2,3-dioxo-L-gulonate

cyclic- 3,4-O-oxalyl-L-threonate

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

dehydroascorbate (bicyclic form)

cyclic-2,3-O-oxalyl-L-threonate

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

ammonia

L-dehydro-ascorbate

4-(β-D-ribofuranosyl)-N-succinylaminobenzene 5'-phosphate

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

α-D-galacturonate 1-phosphate

L-xylo-hex-3-ulono-1,4-lactone

L-gulono-1,4-lactone

(2R,3S)-3-methylmalate

citraconate

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

cyclohexane-1-carbonyl-CoA

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl 5-phosphate]-D-ribitol

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol

(R)-mevalonate diphosphate

2-(α-hydroxyethyl)thiamine diphosphate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

2-oxoadipate

7-mercaptoheptanoylthreonine

7-mercaptoheptanoate

7-oxoheptanoate

2-oxosuberate

cis-(homo)₃aconitate

2-oxopimelate

cis-(homo)₂aconitate

oxalosuccinate

4-amino-2-methyl-5-pyrimidinemethanol

dialurate

(R)-1-amino-2-propanol O-2-phosphate

S-ribosyl-L-homocysteine

autoinducer 2

α-D-glucosamine 1-phosphate

3-methyl-2-butenal

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

2-C-methyl-D-erythritol 4-phosphate

α-ribazole

(S)-4-amino-5-oxopentanoate

(2S)-lactyl-2-diphospho-5'-guanosine

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

ethanolamine

α-D-ribose 1,5-bisphosphate

(L-threonylcarbamoyl)adenylate

D-gluconate 6-phosphate

Coα-[α-(5-hydroxybenzimidazolyl)]-Coβ-methylcobamide

coenzyme F₃₉₀-A

nigerose

N-(2,3-dihydroxybenzoyl)-L-serine trimer

(2S)-2-isopropylmalate

2-isopropylmaleate

citrate

4-amino-4-deoxychorismate

2-maleylacetate

L-canavanine

(S)-2,3,4,5-tetrahydrodipicolinate

hydrogen peroxide

shikimate 3-phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

shikimate

hexulose 6-phosphate

5,6-dimethylbenzimidazole

α-ribazole 5'-phosphate

3-ureidopropanoate

L-histidinol phosphate

DNA without lesion

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

coproporphyrinogen III

1-deoxy-L-glycero-tetrulose 4-phosphate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

N²-succinyl-L-glutamate 5-semialdehyde

N²-succinylglutamate

4-acetamidobutanal

4-acetamidobutanoate

4-prenylphlorisobutyrophenone

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

nicotinate adenine dinucleotide

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

histidinal

histidinol

(S)-ureidoglycolate

urea

(S)-dihydroorotate

preuroporphyrinogen

5-aminolevulinate

porphobilinogen

3-phosphooxypyruvate

(R)-mevalonate

(R)-5-phosphomevalonate

prenyl diphosphate

carbon monoxide

prephenate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

(2E,6E)-farnesyl diphosphate

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

L-homocysteine

DNA with lesion

phenylacetate

adenosylcobalamin

Mg-protoporphyrin

adenosylcobinamide

adenosylcobyrate

cob(I)inamide

cobalt-factor III

cobalt-sirohydrochlorin

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-5A

adenosyl-cobinamide phosphate

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

cobalt-precorrin-3

cobalt-precorrin-4

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

hydrogen cyanide

N₂

protoporphyrin IX

uroporphyrinogen-I

coproporphyrinogen I

uroporphyrinogen-III

protoporphyrinogen IX

siroheme

hydrogen sulfide

oxygen

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

3-phospho-D-glyceroyl-phosphate

2,3-diphospho-D-glycerate

2-O-(α-D-mannosyl)-3-phospho-D-glycerate

2-O-(α-D-mannosyl)-D-glycerate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(R)-citramalate

(S)-citramalate

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol

(S)-2-hydroxyglutarate

superoxide

monodehydroascorbate radical

hydroxyl radical

nitric oxide

dimethyl sulfide

S-methyl-L-methionine

glutathione

thiocyanate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

coenzyme M

trimethyl sulfonium

sulfate

sulfite

selenite

selenate

thiosulfate

OH^-

hydrogensulfite

hydrogencarbonate

sulfide(2-)

phosphate

diphosphate

triphosphate

Fe³⁺

Na⁺

ammonium

H⁺

Fe²⁺

Co²⁺

Mg²⁺

agmatine

dehydrospermidine

spermidine

putrescine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

glycerophosphoglycerol

glycerophosphoserine

sn-glycero-3-phosphoethanolamine

allantoate

(S)-(+)-allantoin

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

methane

(indol-3-yl)acetate

phenylacetyl-CoA

succinyl-CoA

acetyl-CoA

3'-dephospho-CoA

2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

glutaryl-CoA

(E)-glutaconyl-CoA

malonyl-CoA

isobutanoyl-CoA

2-methylacetoacetyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

crotonyl-CoA

(S)-3-hydroxybutanoyl-CoA

propanoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

L-galactono-1,4-lactone

cis-dienelactone

trans-dienelactone

D-glucono-1,5-lactone

FMN

FAD

FMNH₂

(S)-NADHX

(R)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

menaquinol-8

demethylmenaquinol-8

methyl-CoM

coenzyme A

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

oxidized coenzyme F₄₂₀-0

oxidized coenzyme F₄₂₀-2

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

demethylated 7,8-dihydromethanopterin

7,8-dihydromethanopterin

5,10-methylene-tetrahydromethanopterin

5,6,7,8-tetrahydrofolate

tetrahydropteroyl tri-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

riboflavin

L-ascorbate

nicotinate

pyridoxamine 5'-phosphate

pyridoxal 5'-phosphate

menadione

(S)-1-pyrroline-5-carboxylate

Coα-[α-(5-hydroxybenzimidazolyl)]-cobamide

precorrin-2

precorrin-1

precorrin-6B

precorrin-7

precorrin-8x

precorrin-5

precorrin-3B

precorrin-4

sirohydrochlorin

hydantoin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol

7,8-dihydroneopterin 3'-triphosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropteroate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

adenine

2'-deoxyadenosine

2'-deoxyguanosine

guanosine

inosine

xanthosine

adenosine

dAMP

dGMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

GMP

IMP

XMP

AMP

ITP

GTP

ATP

orotate

dTMP

UDP

UTP

dUDP

dUTP

dTDP

dTTP

dCDP

dCTP

CTP

CDP

cytosine

uracil

dCMP

dUMP

5,6-dihydrouracil

5,6-dihydrothymine

UDP-α-D-galacturonate

UDP-α-D-glucose

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-glucosamine

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

cytidine

uridine

CMP

UMP

isoguanine

(indole-3-yl)acetonitrile

4-hydroxybenzoate

salicylaldehyde

benzaldehyde

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

menadiol

salicylate

4-aminobenzoate

benzoate

L-kynurenine

L-α-amino-ε-keto-pimelate

L-2-aminoadipate

L-serine

β-alanine

glycine

L-leucine

L-proline

L-glutamine

L-glutamate

L-lysine

L-arginine

N^ω-hydroxy-L-arginine

L-histidine

L-aspartate

L-cysteine

L-tyrosine

L-threonine

L-asparagine

L-tryptophan

L-aspartyl-4-phosphate

seleno-L-homocysteine

L-selenomethionine

3-phospho-L-serine

N-carbamoylglycine

N-acetyl-L-ornithine

N-acetyl-L-methionine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

O-acetyl-L-homoserine

L-citrulline

L-valine

L-isoleucine

L-glutamate-5-semialdehyde

L-ornithine

L-homoserine

S-sulfo-L-cysteine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-aspartate 4-semialdehyde

O-phospho-L-homoserine

meso-diaminopimelate

L-selenocysteine

L-methionine

L,L-diaminopimelate

chorismate

fumarate

succinate

(S)-malate

3-(carbamoylamino)-2-methylpropanoate

(-)threo-iso(homo)₃citrate

trihomocitrate

(-)threo-iso(homo)₂citrate

dihomocitrate

cis-aconitate

(2R)-homocitrate

(1R,2S)-homoisocitrate

cis-homoaconitate

D-threo-isocitrate

(S)-lactate

(R)-lactate

pyruvate

acetate

formate

propanoate

octanoate

apo-4'-lycopenoate

D-gluconate

aldehydo-D-glucuronate

aldehydo-D-galacturonate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

2-oxoglutarate

glyoxylate

2-oxobutanoate

methylglyoxal

diacetyl

glycolaldehyde

1-octanal

acetaldehyde

D-glyceraldehyde

α-D-glucopyranose

β-D-glucopyranose

methanol

ethanol

glycerol

(3R)-linalool

(3S)-linalool

myo-inositol

1D-myo-inositol 1-monophosphate

1D-myo-inositol 3-monophosphate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

geranyl diphosphate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

torulene

apo-4'-lycopenal

all-trans-3,4-didehydrolycopene

4'-apo-β-carotenal

phytyl diphosphate

3-octaprenyl-4-hydroxybenzoate

phlorisovalerophenone

deoxyhumulone

4-prenylphlorisovalerophenone

deoxycohumulone

ferric-[N-(2,3-dihydroxybenzoyl)-L-serine trimer] complex

1-(β-D ribofuranosyl)nicotinamide

maltotriose

maltotetraose

maltohexaose

maltoheptaose

maltopentaose

sucrose

keto-D-fructose

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

D-ribulose-1,5-bisphosphate

sucrose 6^F-phosphate

GDP-α-D-mannose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-erythrose 4-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-ribulose 5-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

aldehydo-L-galactonate

L-gulonate

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-ATP

8-oxo-GTP

8-oxo-dGTP

cyclic-AMP

1-(5-phospho-β-D-ribosyl)-AMP

adenylo-succinate

2-hydroxy-dATP

5-hydroxy-CTP

β-nicotinamide D-ribonucleotide

2-iminosuccinate