an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

H₂O

3-deoxy-D-arabino-heptulosonate 7-phosphate

phosphoenolpyruvate

CO₂

prephenate

3-dehydroquinate

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

3-dehydroshikimate

shikimate

β-nicotinate D-ribonucleotide

acetyl phosphate

prephytoene diphosphate

hydrogen peroxide

glycerone phosphate

nicotinate adenine dinucleotide

(R)-5-phosphomevalonate

(R)-mevalonate

isopentenyl diphosphate

(R)-mevalonate diphosphate

prenyl diphosphate

coproporphyrinogen III

xanthine

β-D-ribosylnicotinate

glycolate

2-phosphoglycolate

(R)-4'-phosphopantothenate

(R)-pantothenate

phosphocholine

pseudouridine 5'-phosphate

3-deoxy-D-glycero-2,5-hexodiulosonate

2-dehydro-3-deoxy-D-gluconate 6-phosphate

2-amino-2-deoxy-D-gluconate 6-phosphate

dihydroxyacetone

N-acetyl-D-muramate 6-phosphate

6-phospho D-glucono-1,5-lactone

D-gluconate 6-phosphate

α-D-glucosamine 1-phosphate

4'-phosphopantetheine

thiamine diphosphate

2-dehydro-3-deoxy-D-gluconate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

(lipoyl)adenylate

S-acetyldihydrolipoamide

dihydrolipoamide

2-(α-hydroxyethyl)thiamine diphosphate

urea

enol-phenylpyruvate

propanoyl phosphate

ethanolamine

cis,cis-muconate

(+)-muconolactone

muconolactone

(R)-mandelate

(S)-mandelate

glutathione disulfide

2-dehydropantoate

pregn-5-ene-3,20-dione

pregn-5-ene-3,20-dione-17-ol

5-androstene-3,17-dione

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

5-hydroxy-3-[(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

methylsalicylate

salicyl alcohol

4-pyridoxolactone

4-acetamidobutanoate

4-acetamidobutanal

N²-succinylglutamate

N²-succinyl-L-glutamate 5-semialdehyde

2,3-dioxo-L-gulonate

3-keto-L-gulonate

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

propionamide

(indol-3-yl)acetamide

4-guanidinobutanoate

4-guanidinobutyramide

acrylate

acrylamide

S-ribosyl-L-homocysteine

3-hydroxypropanal

1,3-propanediol

autoinducer 2

hydroxypyruvate

oxaloacetate

1,6-anhydro-N-acetyl-β-muramate

dehydroascorbate (bicyclic form)

L-dehydro-ascorbate

3-keto-L-gulonate 6-phosphate

(R)-4'-phosphopantothenoyl-L-cysteine

hypotaurine

4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate

3α,12α-dihydroxy-7-oxo-5β-cholan-24-oate

7-epicholate

(1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1 (10),2-dien-4-oate

(S)-4-hydroxy-2-oxohexanoate

(2Z,4Z)-2-hydroxyhexa-2,4-dienoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

(2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxylate

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA

3-methyl-2-oxobutanoate

acetoacetate

2-iminoacetate

(S)-2-acetolactate

pseudouridine

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

quinolinate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

N¹-(5-phospho-β-D-ribosyl)glycinamide

2-carboxy-L-xylonolactone

cyclic-2,3-O-oxalyl-L-threonate

ammonia

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

cyclic- 3,4-O-oxalyl-L-threonate

2-carboxy-L-threo-pentonate

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

sulfate

hydrogencarbonate

superoxide

sulfite

hydrogensulfite

phosphate

diphosphate

Cd²⁺

Cu²⁺

Mg²⁺

Fe²⁺

ammonium

H⁺

trimethyl sulfonium

dimethyl sulfide

glutathione

N-acetyl-D-galactosamine 6-O-sulfate

2-sulfinoacetaldehyde

monodehydroascorbate radical

(S)-3-hydroxy-isobutanoate

5,10-methenyltetrahydrofolate mono-L-glutamate

(S)-methylmalonate-semialdehyde

(R)-methylmalonate-semialdehyde

1-oleoyl-2-lyso-glycerone phosphate

α-D-glucosamine 6-phosphate

3-phospho-D-glyceroyl-phosphate

(R)-glycerate

2-phospho-D-glycerate

3-phospho-D-glycerate

sn-glycerol 3-phosphate

oxygen

protoporphyrinogen IX

uroporphyrinogen-III

protoporphyrin IX

protoheme

L-homocysteine

4-methylphenol

(R)-4-hydroxymandelate

(S)-4-hydroxymandelate

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

2-iminosuccinate

L-lysine

L-arginine

L-glutamate

L-serine

L-glutamine

glycine

L-alanine

L-leucine

β-alanine

L-phenylalanine

L-methionine

L-cysteine

L-asparagine

L-aspartate

L-ornithine

L-tyrosine

N-acetyl-L-ornithine

N-acetyl-L-citrulline

L-citrulline

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

N-acetyl-L-glutamate

D-alanine

AMP

ATP

ADP

5'-deoxyadenosine

GDP

GTP

dADP

dATP

dGDP

dGTP

GMP

ppGpp

pppGpp

IMP

2'-deoxyadenosine

2'-deoxyguanosine

hypoxanthine

2'-deoxyinosine

5-chloro-5-deoxyribose 1-phosphate

5'-chloro-5'-deoxyadenosine

XMP

adenylo-succinate

cyclic-AMP

GDP-α-D-mannose

5'-deoxy-5'-fluoroadenosine

NADP⁺

NAD⁺

NADPH

NADH

CDP-choline

UDP-α-D-galactose

UDP-α-D-glucose

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-mannosaminuronate

preQ₁

adenine

guanine

uracil

thymine

cyclic di-3',5'-guanylate

dTMP

dUMP

dCMP

dTDP

dCDP

dUDP

dUTP

dCTP

dTTP

CDP

UDP

β-nicotinamide D-ribonucleotide

CTP

UTP

CMP

UMP

2'-deoxyuridine

thymidine

2'-deoxycytidine

adenosine

inosine

guanosine

xanthosine

uridine

cytidine

D-mannonate

D-altronate

1-(β-D ribofuranosyl)nicotinamide

5-dehydro-4-deoxy-D-glucuronate

β-D-cellobiose

unsaturated gellan tetrasaccharide

sucrose

4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine

4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl--D-galactosamine 6-sulfate

β-D-Glcp-(1→4)-α-L-Rhap-(1→3)-D-Glcp

aldehydo-D-galacturonate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

α-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-glucopyranose 1-phosphate

α-D-galactose 6-phosphate

β-D-galactose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

6-deoxy-5-ketofructose 1-phosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-ribose-1-phosphate

5-fluoro-5-deoxy-D-ribose 1-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-xylulose 5-phosphate

L-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-ribulose 5-phosphate

L-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

sucrose 6^F-phosphate

D-ribulose-1,5-bisphosphate

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

glycerol

β-D-fructofuranose

aldehydo-D-ribose

β-D-ribofuranose

α-D-ribofuranose

β-D-galactopyranose

α-D-galactopyranose

β-D-glucopyranose

α-D-glucopyranose

D-xylulose

keto-D-fructose

N-acetylmuramate

N-acetyl-α-D-muramoyl-L-alanine(1-)

N-acetyl-β-D-galactosamine

N-acetyl-β-D-glucosamine

salicylaldehyde

apo-4'-lycopenal

15-cis-phytoene

all-trans phytofluene

apo-4'-lycopenoate

all-trans-retinol

all-trans-retinyl palmitate

3-oxo-24-ethyl-cholest-5-ene

sitosterol

3-oxo-24-ethyl-cholest-4-ene

3-oxo-24-ethyl-26-hydroxy-cholest-4-ene

3-oxo-24-ethyl-cholest-4-en-26-oyl-CoA

3-oxo-24-ethyl-cholest-4,24-dien-26-oyl-CoA

3-oxo-24-(isopropanoyl)-cholest-4,24-dien-26-oyl-CoA

3,24-dioxo-cholest-4-en-26-oate

3-oxo-24-ethyl-cholest-4-en-26-oate

3-oxo-24-ethyl-26-al-cholest-4-ene

(2E,6E)-farnesyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

2-cis,6-trans,10-trans-geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

geranylgeranyl diphosphate

all-trans-heptaprenyl diphosphate

1-oleoyl-2-palmitoyl-phosphatidylglycerol

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

dioleoyl phosphatidate

1-(oleoyl)-sn-glycero-3-phosphoethanolamine

1-oleoyl-sn-glycerol 3-phosphate

1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate

phytosphingosine

phytosphingosine 1-phosphate

sphinganine 1-phosphate

D-erythro-sphinganine

ethanol

methanol

fluoroacetaldehyde

methylglyoxal

benzaldehyde

acetaldehyde

1-octanal

formaldehyde

1-propanal

diacetyl

(R)-acetoin

palmitate

octanoate

oleate

pyruvate

formate

acetate

propanoate

(S)-lactate

(R)-lactate

chorismate

fumarate

(S)-malate

2-oxoglutarate

4-(methylsulfanyl)-2-oxobutanoate

glyoxylate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

salicylate

benzoate

(R)-pantoate

fluoroacetate

D-tagaturonate

6-hydroxy-2-cyclohexen-one-carboxylate

salicyl-6-hydroxy-2-cyclohexene-on-oyl

urate

preQ₀

7,8-dihydropteroate

5,6,7,8-tetrahydrofolate

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

FMN

riboflavin

FMNH₂

reduced riboflavin

nicotinate

L-ascorbate

thiamine

nicotinamide

pyridoxal

coenzyme A

(R)-lipoate

(R)-NADHX

(S)-NADHX

acetyl-CoA

2-methylacetoacetyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

malonyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

CoA-disulfide

3'-dephospho-CoA

oleoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

hexadecanedioyl-CoA

propanoyl-CoA

(S)-malyl-CoA

androsterone

pregnenolone

testosterone

17-β-hydroxy-5-α-androstan-3-one

progesterone

campest-4-en-3-one

(indol-3-yl)acetate

methyl (indol-3-yl)acetate

5-α-pregnane-3,20-dione

cortisone

4,5α-dihydrocortisone

cholest-4-en-3-one

coprostanone

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oate

3α,7α,12β-trihydroxy-5β-cholan-24-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

3-oxocholest-4,24-dien-26-oyl-CoA

24-hydroxy-3-oxocholest-4-en-26-oyl-CoA

3,24-dioxocholest-4-en-26-oyl-CoA

3-oxochol-4-en-24-oyl-CoA

3-oxochol-4,22-dien-24-oyl-CoA

22-hydroxy-3-oxochol-4-en-24-oyl-CoA

3,22-dioxochol-4-en-24-oyl-CoA

3-oxo-4-pregnene-20-carboxyl-CoA

3-oxo-4,17-pregnadiene-20-carboxyl-CoA

17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA

(25S)-3-oxocholest-4-en-26-oate

(25S)-26-oxocholest-4-en-3-one

(25S)-26-hydroxycholest-4-en-3-one

17-α-hydroxypregnenolone

cholest-5-en-3-one

cholesterol

3-β-hydroxyandrost-5-en-17-one

isocholate

3-dehydrocholate

glycocholate

cholate

campest-4-en-3β-ol

5α-androstane-3,17-dione

androst-4-ene-3,17-dione

androsta-1,4-diene-3,17-dione

9α-hydroxyandrosta-1,4-diene-3,17-dione

3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

acetamide

sn-glycero-3-phosphoethanolamine

sn-glycero-3-phosphocholine

glycerophosphoserine

glycerophosphoglycerol

choline

agmatine

spermidine

putrescine

cadaverine