an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

α-D-galacturonate 1-phosphate

L-xylo-hex-3-ulono-1,4-lactone

L-gulono-1,4-lactone

4-amino-2-methyl-5-pyrimidinemethanol

S-ribosyl-L-homocysteine

autoinducer 2

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

(2S)-lactyl-2-diphospho-5'-guanosine

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

cyclohexane-1-carbonyl-CoA

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

dialurate

(R)-1-amino-2-propanol O-2-phosphate

quinolinate

(L-threonylcarbamoyl)adenylate

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

hydrogen peroxide

L-canavanine

carbon monoxide

4-prenylphlorisobutyrophenone

α-ribazole

5,6-dimethylbenzimidazole

α-ribazole 5'-phosphate

nigerose

hexulose 6-phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

(R)-5-phosphomevalonate

S-methyl-5'-thioadenosine

5-deoxy-α-ribose 1-phosphate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

urea

α-D-ribose 1,5-bisphosphate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

L-histidinol phosphate

2-carboxy-L-threo-pentonate

2-carboxy-L-xylonolactone

2,3-dioxo-L-gulonate

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

dehydroascorbate (bicyclic form)

1-deoxy-L-glycero-tetrulose 4-phosphate

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

ammonia

(2S)-2-isopropylmalate

L-dehydro-ascorbate

2-isopropylmaleate

S-adenosyl 3-(methylsulfanyl)propylamine

(5S)-5-benzyl-hydantoin

(5R)-5-benzyl-hydantoin

3-ureidopropanoate

5-oxo-L-proline

nicotinate adenine dinucleotide

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

prephenate

γ-L-glutamyl 5-phosphate

(S)-dihydroorotate

hydrogenobyrinate

4-amino-4-deoxychorismate

orotidine 5'-phosphate

coproporphyrinogen III

5-carboxymethyl-2-hydroxymuconate

shikimate

2-dehydropantoate

N-(5-phosphoribosyl)-anthranilate

anthranilate

hydroxypyruvate

oxalosuccinate

N-acetylglutamyl-phosphate

α-D-glucosamine 1-phosphate

arsenite

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

carbamoyl phosphate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

5-amino-6-(D-ribitylamino)uracil

thiamine diphosphate

preuroporphyrinogen

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

3-phosphooxypyruvate

thiamine phosphate

2-phosphoglycolate

glycolate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

β-nicotinate D-ribonucleotide

β-D-ribosylnicotinate

phosphoenolpyruvate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

glycerone phosphate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

histidinal

histidinol

L-β-lysine

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

hydrogenobyrinate a,c-diamide

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

citrate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

N-acetyl-L-glutamate 5-semialdehyde

(R)-mevalonate

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

porphobilinogen

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

coenzyme B

methanophenazine

CoB-CoM heterodisulfide

dihydromethanophenazine

isopentenyl diphosphate

prenyl diphosphate

O-ureido-L-homoserine

canavaninosuccinate

L-arginino-succinate

H₂

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

3-dehydroquinate

3-dehydroshikimate

H₂O

4'-phosphopantetheine

oxaloacetate

CO₂

monodehydroascorbate radical

dimethyl sulfide

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

coenzyme M

sulfate

molybdate

hydrogencarbonate

sulfite

nitrite

nitrate

trithionate

OH^-

hydrogensulfite

selenate

phosphate

triphosphate

diphosphate

H⁺

ammonium

Fe²⁺

Mg²⁺

Co²⁺

trimethyl sulfonium

agmatine

putrescine

dehydrospermidine

spermidine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

(indol-3-yl)acetate

phenylacetate

glutaryl-CoA

(E)-glutaconyl-CoA

malonyl-CoA

4-hydroxybenzoyl-CoA

isobutanoyl-CoA

phenylacetyl-CoA

acetyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

3'-dephospho-CoA

crotonyl-CoA

(S)-3-hydroxybutanoyl-CoA

propanoyl-CoA

acetoacetyl-CoA

L-galactono-1,4-lactone

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

methyl-CoM

molybdopterin

coenzyme A

oxidized coenzyme F₄₂₀-0

MoO₂-molybdopterin cofactor

guanylyl molybdenum cofactor

N⁵-methyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

L-ascorbate

nicotinate

riboflavin

menadione

(S)-1-pyrroline-5-carboxylate

precorrin-7

precorrin-8x

precorrin-6B

precorrin-6A

precorrin-5

precorrin-4

precorrin-3B

precorrin-3A

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-5A

precorrin-2

precorrin-1

sirohydrochlorin

cobyrinate

adenosylcobalamin

hydantoin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

molybdopterin adenine dinucleotide

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

cyclic pyranopterin phosphate

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydropteroate

adenine

2'-deoxyadenosine

2'-deoxyguanosine

guanosine

inosine

xanthosine

adenosine

hypoxanthine

dAMP

dGMP

dIMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

IMP

XMP

GMP

AMP

XTP

ITP

GTP

ATP

orotate

cytosine

uracil

dCMP

5,6-dihydrouracil

5,6-dihydrothymine

dUMP

dTMP

dUDP

dUTP

dTDP

dTTP

dCDP

dCTP

UTP

CTP

CDP

UDP

UDP-α-D-galacturonate

UDP-α-D-galactofuranose

UDP-α-D-glucuronate

UDP-α-D-glucose

UDP-α-D-galactose

UDP-N-acetyl-α-D-glucosamine

dTDP-α-D-glucose

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

cytidine

uridine

CMP

UMP

(indole-3-yl)acetonitrile

3-hexaprenyl-4-hydroxybenzoate

4-hydroxybenzoate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

menadiol

4-aminobenzoate

chorismate

succinate

fumarate

L-aspartate

(S)-malate

3-(carbamoylamino)-2-methylpropanoate

(2R)-homocitrate

(1R,2S)-homoisocitrate

cis-homoaconitate

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

D-threo-isocitrate

(S)-lactate

(R)-glycerate

propanoate

acetate

formate

pyruvate

(R)-pantoate

aldehydo-D-galacturonate

aldehydo-D-glucuronate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

2-oxobutanoate

2-oxoglutarate

L-cysteine

L-tyrosine

L-threonine

L-glutamine

L-serine

glycine

L-asparagine

L-arginine

L-lysine

L-histidine

L-glutamate

L-tryptophan

D-aspartate

seleno-L-homocysteine

L-selenomethionine

L-aspartyl-4-phosphate

N-carbamoylglycine

N-acetyl-L-ornithine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

3-phospho-L-serine

L-citrulline

L-glutamate-5-semialdehyde

O-phospho-L-homoserine

L-homoserine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-homocysteine

L-ornithine

L-aspartate 4-semialdehyde

meso-diaminopimelate

L-methionine

L-valine

L-leucine

L-isoleucine

L-proline

L,L-diaminopimelate

β-alanine

diacetyl

acetaldehyde

D-glyceraldehyde

α-D-glucopyranose

β-D-glucopyranose

(3R)-linalool

(3S)-linalool

myo-inositol

1D-myo-inositol 2-monophosphate

1D-myo-inositol 1-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 5-monophosphate

1D-myo-inositol 4-monophosphate

1D-myo-inositol 3-monophosphate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

geranyl diphosphate

(2E,6E)-farnesyl diphosphate

phytyl diphosphate

3-nonaprenyl-4-hydroxybenzoate

3-heptaprenyl-4-hydroxybenzoate

3-decaprenyl-4-hydroxybenzoate

3-octaprenyl-4-hydroxybenzoate

all-trans-nonaprenyl diphosphate

all-trans-hexaprenyl diphosphate

all-trans-heptaprenyl diphosphate

all-trans-decaprenyl diphosphate

all-trans-octaprenyl diphosphate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

6-O-trans-keto-mycolyl-trehalose 6-phosphate

trehalose-trans-keto-mono-mycolate

6-O-cis-keto-mycolyl-trehalose 6-phosphate

trehalose-cis-keto-mono-mycolate

6-O-trans-methoxy-mycolyl-trehalose 6-phosphate

trehalose-trans-methoxy-mono-mycolate

6-O-cis-methoxy-mycolyl-trehalose 6-phosphate

trehalose-cis-methoxy-mono-mycolate

6-O-α-mycolyl-trehalose 6-phosphate

α, α'-trehalose 6-α-mycolate

phlorisovalerophenone

deoxyhumulone

4-prenylphlorisovalerophenone

deoxycohumulone

1-(β-D ribofuranosyl)nicotinamide

sucrose

α,α-trehalose

N-acetyl-α-D-glucosamine 1-phosphate

keto-D-fructose

β-D-fructofuranose

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

D-ribulose-1,5-bisphosphate

sucrose 6^F-phosphate

α,α-trehalose 6-phosphate

GDP-α-D-mannose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-ribulose 5-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

aldehydo-L-galactonate

L-gulonate

1-(5-phospho-β-D-ribosyl)-AMP

cyclic-AMP

5'-deoxyadenosine

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-ATP

β-nicotinamide D-ribonucleotide

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

adenosylcobyrate

adenosyl-cobinamide phosphate

adenosyl-cob(III)yrinate a,c-diamide

cob(I)yrinate a,c-diamide

cobalt-factor III

cobalt-sirohydrochlorin

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

Mg-protoporphyrin

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

protoheme

uroporphyrinogen-III

protoporphyrin IX

uroporphyrinogen-I

protoporphyrinogen IX

siroheme

oxygen

hydrogen sulfide

sn-glycerol 1-phosphate

2-O-(α-D-mannosyl)-D-glycerate

2-O-(α-D-mannosyl)-3-phospho-D-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol