an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

N⁵-carboxyaminoimidazole ribonucleotide

dialurate

3-amino-1-hydroxyacetone 1-phosphate

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

1-(methylsulfanyl)xylulose 5-phosphate

urea

butanoyl phosphate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

8-amino-7-oxononanoate

CO₂

pimeloyl-CoA

pimelate

H₂O

3-dehydroquinate

3-deoxy-D-arabino-heptulosonate 7-phosphate

phosphoenolpyruvate

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

3-dehydroshikimate

shikimate

S-adenosyl 3-(methylsulfanyl)propylamine

α-D-glucosamine 1-phosphate

5-amino-6-(D-ribitylamino)uracil

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

1-deoxy-L-glycero-tetrulose 4-phosphate

prenyl diphosphate

(S)-2-acetolactate

O-acetyl-L-serine

hydrogen selenide

(R)-4'-phosphopantothenate

(R)-pantothenate

thiamine diphosphate

thiamine phosphate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

glycerone phosphate

isopentenyl diphosphate

2-C-methyl-D-erythritol 4-phosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

(S)-2,3,4,5-tetrahydrodipicolinate

α-ribazole 5'-phosphate

α-ribazole

(R)-1-amino-2-propanol O-2-phosphate

hydrogenobyrinate a,c-diamide

hydrogenobyrinate

D-glycero-β-D-manno-heptose 1-phosphate

D-glycero-β-D-manno-heptose 1,7-bisphosphate

ADP-L-glycero-β-D-manno-heptose

γ-L-glutamyl 5-phosphate

nicotinate adenine dinucleotide

β-nicotinate D-ribonucleotide

5-(methylsulfanyl)-ribulose 1-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

hydroxylamine

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

xanthine

(L-threonylcarbamoyl)adenylate

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

preuroporphyrinogen

porphobilinogen

prephenate

H₂

DNA without lesion

4-pyridoxolactone

orotidine 5'-phosphate

histidinol

L-histidinol phosphate

α-D-galactosyl-diphosphoundecaprenol

(S)-dihydroorotate

carbamoyl phosphate

anthranilate

N-(5-phosphoribosyl)-anthranilate

4-phosphooxy-L-threonine

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

3-phosphooxypyruvate

2-dehydropantoate

5,6-dimethylbenzimidazole

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

histidinal

coproporphyrinogen III

1-piperideine 6-carboxylate

pyruvic oxime

ammonia

4-aminobutanoate

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

O-ureido-L-homoserine

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

dihydroxyacetone

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

L-canavanine

canavaninosuccinate

L-arginino-succinate

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

(2S)-2-isopropylmalate

dethiobiotin

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

2-succinylbenzoate

3-deoxy-D-manno-octulosonate 8-phosphate

3-deoxy-α-D-manno-2-octulosonate

lipid IV_A

lipid A disaccharide (E. coli)

lipid X

oxaloacetate

malonate

7,8-diaminopelargonate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

(S)-2-amino-6-oxohexanoate

carbon monoxide

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

isochorismate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

1,4-dihydroxy-2-naphthoate

1,4-dihydroxy-2-naphthoyl-CoA

hydroxypyruvate

hydrogen peroxide

3-methyl-2-oxobutanoate

4-amino-2-methyl-5-pyrimidinemethanol

quinolinate

autoinducer 2

S-ribosyl-L-homocysteine

coenzyme A

5,6,7,8-tetrahydrofolate

tetrahydropteroyl tri-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

preQ₀

thiamine

riboflavin

nicotinate

nicotinamide

pyridoxal

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

pyridoxine

pyridoxamine 5'-phosphate

pyridoxamine

FMN

FMNH₂

FAD

NADPH

NADH

NADP⁺

NAD⁺

(R)-NADHX

(S)-NADHX

5,10-methenyltetrahydrofolate mono-L-glutamate

1-oleoyl-2-lyso-glycerone phosphate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

2,3-diphospho-D-glycerate

3-phospho-D-glyceroyl-phosphate

(R)-glycerate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 3-phosphate

hydrogen sulfide

oxygen

uroporphyrinogen-III

protoporphyrinogen IX

uroporphyrinogen-I

protoporphyrin IX

siroheme

protoheme

N₂

adenosyl-cobinamide phosphate

cobalt-precorrin-5A

cobalt-precorrin-4

cobalt-precorrin-6A

cobalt-precorrin-5B

cobalt-precorrin-6B

cobalt-precorrin-8

cobalt-precorrin-7

cobalt-sirohydrochlorin

cobalt-precorrin-3

cobalt-factor III

adenosylcobyrate

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobalamin 5'-phosphate

adenosylcobinamide-GDP

adenosylcobalamin

cobyrinate

cob(II)yrinate a,c-diamide

cob(II)yrinate c-monoamide

cob(I)alamin

adenosylcobinamide

cob(I)inamide

cob(I)yrinate a,c-diamide

DNA with lesion

L-α-amino-ε-keto-pimelate

L-alanine

glycine

L-serine

L-leucine

L-glutamine

L-proline

L-lysine

L-histidine

L-arginine

L-glutamate

D-glutamate

β-alanine

L-citrulline

L-asparagine

L-methionine

L-aspartate

L-threonine

L-tryptophan

L-tyrosine

L-cysteine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-homocysteine

S-sulfo-L-cysteine

O-phospho-L-homoserine

L-homoserine

L-aspartate 4-semialdehyde

L-canaline

L-ornithine

O-succinyl-L-homoserine

L-glutamate-5-semialdehyde

meso-diaminopimelate

L-selenocysteine

L-cystathionine

L,L-diaminopimelate

L-aspartyl-4-phosphate

N-acetyl-L-ornithine

N-carbamoyl-L-aspartate

L-threonine 3-O-phosphate

3-phospho-L-serine

O-acetyl-L-homoserine

N-acetyl-L-glutamate

D-aspartate

D-alanine

D-alanyl-D-alanine

adenylo-succinate

ATP

IMP

ITP

dIMP

dITP

XMP

XTP

GMP

hypoxanthine

ADP

GTP

5'-deoxyadenosine

GDP

2'-deoxyguanosine

dGTP

AMP

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-α-D-galactose

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-mannosaminuronate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-glucosamine

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

CMP-3-deoxy-β-D-manno-octulosonate

xanthosine

guanosine

adenosine

2'-deoxyuridine

2'-deoxycytidine

thymidine

uridine

cytidine

preQ₁

guanine

adenine

uracil

thymine

cyclic di-3',5'-guanylate

dCDP

dTDP

dUDP

dUTP

dCTP

dTTP

dUMP

dCMP

dTMP

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

β-nicotinamide D-ribonucleotide

UMP

CMP

UDP

CDP

UTP

CTP

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydromonapterin

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydroneopterin 3'-phosphate

7,8-dihydropteroate

6,7-dimethyl-8-(1-D-ribityl)lumazine

precorrin-3A

precorrin-2

precorrin-6A

precorrin-6B

precorrin-4

precorrin-3B

precorrin-5

precorrin-8x

precorrin-7

precorrin-1

sirohydrochlorin

orotate

(S)-1-pyrroline-5-carboxylate

4-aminobenzoate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

heptosyl-Kdo₂-lipid IV_A

α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IV_A

heptosyl-Kdo₂-lipid A

α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A

mono-trans,octa-cis-decaprenyl diphosphate

(2E,6E)-farnesyl diphosphate

trans,octacis-decaprenyl phosphate

di-trans,octa-cis-undecaprenyl phosphate

di-trans,octa-cis-undecaprenyl diphosphate

1-oleoyl-sn-glycerol 3-phosphate

dioleoyl phosphatidate

acetyl-CoA

2-methylacetoacetyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

3'-dephospho-CoA

succinyl-CoA

(E)-glutaconyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

oleoyl-CoA

butanoyl-CoA

propanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

(S)-malyl-CoA

crotonyl-CoA

sucrose

glycolaldehyde

aldehydo-D-ribose

α-D-ribofuranose

β-D-ribofuranose

β-D-fructofuranose

N-acetyl-α-D-glucosamine 1-phosphate

N-acetyl-α-D-mannosamine

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

a peptidoglycan dimer (mycobacteria)

a peptidoglycan dimer (E. faecium, tetrapeptide)

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

a peptidoglycan dimer (meso-diaminopimelate containing)

a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

a peptidoglycan with L,D cross-links (mycobacteria)

a peptidoglycan with D,D cross-links (mycobacteria)

a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium)

sucrose 6^F-phosphate

4-phospho-D-erythronate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

1-deoxy-D-xylulose 5-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-arabinose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-glucopyranose 1-phosphate

methylglyoxal

(R)-acetoin

diacetyl

(S)-lactaldehyde

acetaldehyde

formaldehyde

2-oxoglutarate

pyruvate

2-oxobutanoate

glyoxylate

acetate

formate

butanoate

(S)-lactate

(R)-lactate

chorismate

fumarate

succinate

(S)-malate

(R)-pantoate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

2-iminopropanoate

2-iminobutanoate

2-iminosuccinate

ethanol

Fe²⁺

Co²⁺

ammonium

H⁺

trimethyl sulfonium

thiosulfate

hydrogencarbonate

selenide

phosphate

diphosphate

triphosphate

spermidine

putrescine

(2Z)-2-aminobut-2-enoate

2-aminoprop-2-enoate

dimethyl sulfide

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

glutathione

(R)-S-lactoylglutathione

methanethiol