an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

urea-1-carboxylate

nicotinate adenine dinucleotide

prenyl diphosphate

isopentenyl diphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

hydrogen peroxide

2-keto-D-gluconate

2,5-didehydro-D-gluconate

salicyl alcohol

poly(ribitol phosphate)

O-D-alanyl-poly(ribitol phosphate)

coproporphyrinogen III

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

1,4-dihydroxy-2-naphthoyl-CoA

acetyl phosphate

phosphoenolpyruvate

carboxyphosphate

urea

D-gluconate 6-phosphate

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

canavaninosuccinate

L-canavanine

L-arginino-succinate

L-quinate

3-dehydroquinate

shikimate

3-dehydroshikimate

thiamine phosphate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-phospho-β-D-ribosylamine

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

oxalosuccinate

oxaloacetate

citrate

4-imidazolone-5-propanoate

urocanate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

β-nicotinate D-ribonucleotide

CO₂

carbamoyl phosphate

xanthine

glycerone phosphate

H₂O

α-D-glucosamine 1-phosphate

bisorganyltrisulfane

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

4-oxoglutaramate

aminoacetone

ammonia

selenodiglutathione

glutathioselenol

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

oxamate

L-histidinol phosphate

histidinol

histidinal

formamide

glutathione disulfide

thiamine diphosphate

hydrogen selenide

N-Formyl-L-kynurenine

2-dehydro-3-deoxy-D-galactonate 6-phosphate

shikimate 3-phosphate

12α-hydroxy-3-oxochol-4-en-24-oyl-CoA

12α-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA

7α,12α-dihydroxy-3-oxochol-4-en-24-oyl-CoA

acetoacetate

(S)-3-methyl-2-oxopentanoate

(S)-2-acetolactate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-aceto-2-hydroxybutanoate

(2S)-2-isopropylmalate

2-isopropylmaleate

citraconate

(2R,3S)-3-methylmalate

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(D-ribitylamino)uracil

methylsalicylate

3-deoxy-D-arabino-heptulosonate 7-phosphate

DNA without lesion

(S)-dihydroorotate

orotidine 5'-phosphate

β-D-ribosylnicotinate

15-cis-4,4'-diapophytoene

7-carboxy-7-deazaguanine

3-oxopropanoate

3-methyl-2-oxobutanoate

CDP-glycerol

3'-phosphoadenylyl-sulfate

quinolinate

3-oxocholoyl-CoA

allopregnanolone

deoxycholoyl-CoA

12α-hydroxy-3-oxocholan-24-oyl-CoA

5-enolpyruvoyl-shikimate 3-phosphate

2-dehydropantoate

2-dehydro-3-deoxy-D-galactonate

(R)-mevalonate

(R)-5-phosphomevalonate

(R)-mevalonate diphosphate

N-acetyl-α-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol

ManNAc-GlcNAc-PP-undecaprenol

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

2-iminoacetate

anthranilate

3-hydroxyanthranilate

O-acetyl-L-serine

glycolate

diethylphosphate

diethylthiophosphate

dimethylthiophosphate

porphobilinogen

preuroporphyrinogen

6-phospho D-glucono-1,5-lactone

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

imidazole acetol-phosphate

D-erythro-imidazole-glycerol-phosphate

isochorismate

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

hexulose 6-phosphate

(S)-ureidoglycolate

N-carbamoyl-2-oxoglycine

O-ureido-L-homoserine

ethanolamine

(lipoyl)adenylate

N-succinyl-L,L-2,6-diaminopimelate

N-succinyl-2-amino-6-ketopimelate

S-ribosyl-L-homocysteine

autoinducer 2

DNA with lesion

L-homocysteine

4-methylphenol

phosphonoacetaldehyde

(2-aminoethyl)phosphonate

hydrogen cyanide

protoheme

uroporphyrinogen-III

uroporphyrinogen-I

coproporphyrinogen I

protoporphyrin IX

protoporphyrinogen IX

oxygen

hydrogen sulfide

2-iminobutanoate

2-iminopropanoate

2-iminosuccinate

2-chloroacetate

sn-glycerol 3-phosphate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2R)-2,3-dihydroxy-3-methylbutanoate

N-acetyl-D-mannosamine 6-phosphate

(S)-ureidoglycine

(R)-citramalate

(R)-methylmalonate-semialdehyde

(S)-methylmalonate-semialdehyde

3-(all-trans-octaprenyl)benzene-1,2-diol

(S)-3-hydroxy-isobutanoate

2-octaprenylphenol

2-methoxy-6-(all-trans-octaprenyl)phenol

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

parathion

paraoxon

4-nitrophenol

FAD

FADH₂

(S)-NADHX

(R)-NADHX

caldariellaquinol

ubiquinol-8

3-demethylubiquinol-8

caldariellaquinone

NADPH

NADH

NADP⁺

NAD⁺

glycine betaine

superoxide

hydroxyl radical

(2E,6E)-farnesyl diphosphate

pristanate

Fe³⁺

H⁺

ammonium

Fe²⁺

hydrogencarbonate

selenate

sulfate

hydrogensulfite

selenite

OH^-

molybdate

thiosulfate

sulfite

phosphate

diphosphate

triphosphate

chloride

S-(hydroxymethyl)glutathione

methanethiol

glutathione

thiocyanate

S-sulfanylglutathione

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

betaine aldehyde hydrate

betaine aldehyde

choline

(2Z)-2-aminobut-2-enoate

2-aminoprop-2-enoate

agmatine

N¹-acetylspermidine

N¹-acetylspermine

N-acetylputrescine

putrescine

spermidine

spermine

D-alanyl-D-alanine

4-hydroxybenzoate

urate

salicyl-6-hydroxy-2-cyclohexene-on-oyl

6-hydroxy-2-cyclohexen-one-carboxylate

amino-parathion

methyl parathion

hydroquinone

6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol

6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol

2-methoxy-6-all trans-octaprenyl-1,4-benzoquinol

all trans-decaprenyl-2-methoxy-6-1,4-benzoquinol

4-aminophenol

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

baicalein

6,7-dehydrobaicalein

2,3-dihydroxybenzoate

salicylate

preQ₀

coenzyme A

(R)-lipoate

molybdopterin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

MoO₂-molybdopterin cofactor

nicotinate

pyridoxal

pyridoxal 5'-phosphate

pyridoxine

pyridoxine 5'-phosphate

pyridoxamine

pyridoxamine 5'-phosphate

all-trans-retinol

5-α-pregnane-3,20-dione

17-β-hydroxy-5-α-androstan-3-one

campest-4-en-3β-ol

7α-hydroxy-5β-cholestan-3-one

7α,12α-dihydroxy-5β-cholestan-3-one

androst-4-ene-3,17-dione

campest-4-en-3-one

5α-androstane-3,17-dione

deoxycholate

cholate

3-dehydrocholate

5β-cholestane-3α,7α-diol

5β-cholestane-3α,7α,12α-triol

androsterone

5-α-androstan-3α,17β-diol

testosterone

methyl (indol-3-yl)acetate

(indol-3-yl)acetate

D-glucono-1,5-lactone

all-trans-retinyl palmitate

2-methylacetoacetyl-CoA

malonyl-CoA

succinyl-CoA

acetyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

methylacrylyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

(E)-glutaconyl-CoA

isobutanoyl-CoA

choloyl-CoA

3'-dephospho-CoA

crotonyl-CoA

phytenoyl-CoA

(S)-malyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

7-hydroxylauroyl-CoA

18-hydroxystearoyl-CoA

16-hydroxypalmitoyl-CoA

18-hydroxyoleoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

butanoyl-CoA

decanoyl-CoA

octanoyl-CoA

lauroyl-CoA

pristanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

hexadecanedioyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

allantoate

(S)-(+)-allantoin

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

Gro-P-ManNAc-GlcNAc-PP-undecaprenol

chorismate

succinate

L-aspartate

fumarate

(S)-malate

α,ω-9Z-octadecenedioate

cis-aconitate

D-threo-isocitrate

pyruvate

acetate

formate

propanoate

(R)-lactate

butanoate

decanoate

laurate

7-hydroxylaurate

octanoate

18-hydroxyoleate

18-hydroxystearate

16-hydroxypalmitate

(15Z)-tetracosenoate

α-linolenate

linoleate

stearate

oleate

palmitate

phytenate

D-gluconate

orotate

(R)-pantoate

(S)-1-pyrroline-5-carboxylate

carbamate

L-kynurenine

L-serine

β-alanine

(S)-3-amino-2-methylpropanoate

L-proline

L-glutamine

L-alanine

glycine

L-leucine

D-glutamate

L-glutamate

L-arginine

L-lysine

L-histidine

L-tyrosine

L-tryptophan

D-alanine

D-aspartate

L-2-amino-3-oxobutanoate

seleno-L-homocysteine

L-selenomethionine

L-aspartyl-4-phosphate

D-octopine

N-carbamoyl-L-aspartate

formyl-L-isoglutamine

N-formimino-L-glutamate

3-hydroxy-L-kynurenine

trans-4-hydroxy-L-proline

O-acetyl-L-homoserine

L-isoleucine

L-ornithine

L-threonine

L-valine

L-methionine

L-cysteine

L-isoglutamine

L-citrulline

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

O-phospho-L-homoserine

L-glutamate-5-semialdehyde

L-homoserine

L-aspartate 4-semialdehyde

L-canaline

meso-diaminopimelate

2-oxobutanoate

2-oxoglutarate

glyoxylate

sn-glycero-3-phosphoethanolamine

glycerophosphoglycerol

glycerophosphoserine

glycerol

D-sorbitol

L-iditol

methanol

ethanol

all-trans-4,4'-diaponeurosporene

all-trans-4,4'-diapophytofluene

all-trans-4,4'-diapo-ζ-carotene

geranyl diphosphate

trans,octacis-decaprenyl phosphate

all-trans-4,4'-diapolycopene

di-trans,octa-cis-undecaprenyl phosphate

all-trans-octaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

3-octaprenyl-4-hydroxybenzoate

1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate

1-oleoyl-sn-glycerol 3-phosphate

1-(18-hydroxyoleoyl)-sn-glycrol 3-phosphate

betanidin

betanidin quinone

1-(β-D ribofuranosyl)nicotinamide

raffinose

stachyose

sucrose

β-D-fructofuranose

keto-D-fructose

keto-L-sorbose

D-xylulose

L-ribulose

aldehydo-D-ribose

α-D-ribofuranose

β-D-ribofuranose

N-acetyl-α-D-glucosamine 1-phosphate

D-glyceraldehyde

glycolaldehyde

α-D-galactopyranose

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

a peptidoglycan dimer (E. faecium, tetrapeptide)

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium)

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

N-monoacetylchitobiose 6'-phosphate

N,N'-diacetylchitobiose 6'-phosphate

UDP-α-D-glucose

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-galactose

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-mannosaminuronate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-tagatofuranose 1,6-bisphosphate

salicin 6-phosphate

arbutin-6-phosphate

β-D-fructofuranose 6-phosphate

D-tagatofuranose 6-phosphate

D-fructose 6-phosphate

keto-L-tagatose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-ribulose 5-phosphate

L-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-fructofuranose 1-phosphate

methyl β-D-glucoside 6-phosphate

D-galactonate

diacetyl

methylglyoxal

formaldehyde

acetaldehyde

precorrin-2

sirohydrochlorin

dUMP

dTMP

dCDP

dCTP

CDP

dUDP

dUTP

dTDP

dTTP

UTP

CTP

uracil

UDP

dCMP

UMP

CMP

uridine

cytidine

2'-deoxycytidine

2'-deoxyuridine

thymidine

thymine

hypoxanthine

adenine

guanine

isoguanine

preQ₁

xanthosine

adenosine

inosine

guanosine

2'-deoxyguanosine

2'-deoxyadenosine

2'-deoxyinosine

ITP

GTP

ATP

IDP

GDP

ADP

IMP

XMP

AMP

GMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

dAMP

dGMP

6,7-dimethyl-8-(1-D-ribityl)lumazine

7,8-dihydroneopterin 3'-triphosphate

molybdopterin adenine dinucleotide

7,8-dihydroneopterin

7,8-dihydromonapterin

6-(hydroxymethyl)-7,8-dihydropterin

cyclic pyranopterin phosphate

6-carboxy-5,6,7,8-tetrahydropterin

adenylo-succinate

8-oxo-GTP

8-oxo-dGTP

1-(5-phospho-β-D-ribosyl)-AMP

5'-deoxyadenosine

pppGpp

ppGpp

1-(5-phospho-β-D-ribosyl)-ATP

5-hydroxy-CTP

2-hydroxy-dATP

β-nicotinamide D-ribonucleotide

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA