an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

ammonia

enol-phenylpyruvate

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(R)-mevalonate diphosphate

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

S-ribosyl-L-homocysteine

autoinducer 2

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

shikimate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

2-maleylacetate

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

DNA without lesion

O-acetyl-L-serine

oxalate

α-D-ribose 1,5-bisphosphate

S-methyl-5'-thioadenosine

quinolinate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

(E)-3-(methoxycarbonyl)pent-2-enedioate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

7-carboxy-7-deazaguanine

1-phosphatidyl-myo-inositol

1-phosphatidyl-myo-inositol 2-mannose

3-phosphooxypyruvate

citrate

4-aminobutanoate

γ-L-glutamyl 5-phosphate

(R)-5-phosphomevalonate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

(R)-mevalonate

3-dehydroshikimate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

anthranilate

N-(5-phosphoribosyl)-anthranilate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

tetrahydrogeranylgeranyl diphosphate

dihydrogeranylgeranyl diphosphate

β-D-galactosyl-(1→4)-N-acetyl-D-glucosamine

4-prenylphlorisobutyrophenone

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate

(2S)-lactyl-2-diphospho-5'-guanosine

(R)-4'-phosphopantothenoyl-L-cysteine

hydrogen peroxide

N²-succinylglutamate

coenzyme B

CoB-CoM heterodisulfide

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

isochorismate

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

thiamine phosphate

thiamine diphosphate

N⁵-carboxyaminoimidazole ribonucleotide

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

3-hydroxypropanoate

4-methyl-2-oxopentanoate

coproporphyrinogen III

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

1-deoxy-L-glycero-tetrulose 4-phosphate

nicotinate adenine dinucleotide

deethylsimazine

N-ethylammeline

diethylthiophosphate

diethylphosphate

dimethylthiophosphate

carbonic acid

methanophenazine

dihydromethanophenazine

hexulose 6-phosphate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

histidinal

histidinol

5-amino-6-(D-ribitylamino)uracil

carboxyphosphate

2-phosphoglycolate

glycolate

L-histidinol phosphate

(S)-dihydroorotate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

L-canavanine

orotidine 5'-phosphate

5-aminolevulinate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

carbon monoxide

isopentenyl diphosphate

prenyl diphosphate

(S)-2,3,4,5-tetrahydrodipicolinate

4'-phosphopantetheine

(S)-4-amino-5-oxopentanoate

glycerone phosphate

prephenate

porphobilinogen

preuroporphyrinogen

phosphoenolpyruvate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

N-acetylglutamyl-phosphate

L-arginino-succinate

O-ureido-L-homoserine

canavaninosuccinate

H₂

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

oxaloacetate

N-acetyl-L-glutamate 5-semialdehyde

β-nicotinate D-ribonucleotide

β-D-ribosylnicotinate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

CO₂

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

carbamoyl phosphate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

3-methyl-2-oxobutanoate

(2S)-2-isopropylmalate

H₂O

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

DNA with lesion

L-homocysteine

phenylacetate

ethylphosphate

cobalt-factor III

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

Mg-protoporphyrin

cobalt-precorrin-4

cobalt-precorrin-5A

cobalt-sirohydrochlorin

cobalt-precorrin-2

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

uroporphyrinogen-I

protoporphyrin IX

protoporphyrinogen IX

uroporphyrinogen-III

siroheme

hydrogen sulfide

oxygen

2-iminosuccinate

2-chloroacetate

β-D-mannosyl-(C55 ω-saturated dolichyl phosphate)

sn-glycerol 1-phosphate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

ω-saturated C55 dolichol phosphate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(S)-citramalate

3-(all-trans-octaprenyl)benzene-1,2-diol

2-methoxy-6-(all-trans-octaprenyl)phenol

preQ₀

parathion

paraoxon

4-nitrophenol

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

H⁺

ammonium

Mg²⁺

Fe²⁺

Co²⁺

molybdate

sulfite

superoxide

hydrogencarbonate

sulfate

phosphate

triphosphate

diphosphate

chloride

(2E,6E)-farnesyl diphosphate

pristanate

1-oleoyl-2-palmitoyl-phosphatidylglycerol

agmatine

dehydrospermidine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

methanethiol

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

sulfoacetaldehyde

coenzyme M

L-cysteate

3-sulfopyruvate

(2R)-3-sulfolactate

dodecyl sulfate

(2R)-phospho-3-sulfolactate

trans,octacis-decaprenylphospho-β-D-ribofuranose 5-phosphate

cis-dienelactone

trans-dienelactone

D-glucono-1,5-lactone

(S)-3-hydroxy-3-methylglutaryl-CoA

phenylacetyl-CoA

linoleoyl-CoA

α-linolenoyl-CoA

4-hydroxybutanoyl-CoA

3-hydroxypropanoyl-CoA

2-methylacetoacetyl-CoA

3'-dephospho-CoA

isobutanoyl-CoA

succinyl-CoA

acetyl-CoA

phytenoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

7-hydroxylauroyl-CoA

18-hydroxystearoyl-CoA

16-hydroxypalmitoyl-CoA

18-hydroxyoleoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

decanoyl-CoA

lauroyl-CoA

octanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

tributyrin

1,2-dibutyrin

methane

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

glycocholate

cholate

nicotinamide

riboflavin

nicotinate

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

FAD

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

caldariellaquinone

caldariellaquinol

ubiquinol-8

menaquinol-8

demethylmenaquinol-8

3-demethylubiquinol-8

dGDP

dIDP

dITP

IDP

ITP

dADP

cyclic-AMP

hypoxanthine

dATP

dGTP

1-(5-phospho-β-D-ribosyl)-AMP

5'-deoxyadenosine

GTP

GDP

IMP

GMP

XMP

ADP

1-(5-phospho-β-D-ribosyl)-ATP

adenylo-succinate

ATP

AMP

(R)-NADPHX

(S)-NADPHX

adenosine

inosine

guanosine

xanthosine

cytidine

uridine

2'-deoxycytidine

2'-deoxyuridine

cyclic di-3',5'-guanylate

dTTP

dCTP

dUTP

CTP

UTP

dUMP

dTMP

dCMP

CMP

UMP

dTDP

dUDP

dCDP

CDP

UDP

β-nicotinamide D-ribonucleotide

GDP-4-dehydro-α-D-rhamnose

GDP-α-D-mannose

ADP-α-D-glucose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

uracil

adenine

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-glucuronate

UDP-α-D-galactose

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

molybdopterin

methyl-CoM

coenzyme A

oxidized coenzyme F₄₂₀-0

MoO₂-molybdopterin cofactor

thio-molybdenum cofactor

(S)-1-pyrroline-5-carboxylate

precorrin-6B

precorrin-6A

precorrin-8x

precorrin-1

precorrin-2

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

cyclic pyranopterin phosphate

molybdopterin adenine dinucleotide

7,8-dihydroneopterin 3'-triphosphate

6-carboxy-5,6,7,8-tetrahydropterin

orotate

amino-parathion

methyl parathion

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

4-aminophenol

diacetyl

methylglyoxal

acetaldehyde

formaldehyde

(S)-lactaldehyde

D-glyceraldehyde

α-D-ribofuranose

methanol

ethanol

1-dodecanol

myo-inositol

D-ononitol

D-galactosylononitol

1D-myo-inositol 3-monophosphate

1D-myo-inositol 1-monophosphate

galactinol

1-(β-D ribofuranosyl)nicotinamide

keto-D-fructose

N-acetyl-β-D-glucosamine

β-D-fructofuranose

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

D-ribulose-1,5-bisphosphate

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-glucose 6-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

β-D-ribose 5-phosphate

α-D-ribose 5-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

D-gluconate

18-hydroxystearate

16-hydroxypalmitate

18-hydroxyoleate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

geranyl diphosphate

trans,octacis-decaprenyl phosphate

phytyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

geranylgeranyl diphosphate

phlorisovalerophenone

deoxycohumulone

4-prenylphlorisovalerophenone

deoxyhumulone

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

(3E)-2-oxohex-3-enedioate

chorismate

L-aspartate

succinate

fumarate

(S)-malate

α,ω-9Z-octadecenedioate

cis-homoaconitate

trans-aconitate

(2R)-homocitrate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

pyruvate

2-oxoglutarate

2-oxobutanoate

acetate

formate

propanoate

(S)-lactate

(R)-lactate

butanoate

decanoate

7-hydroxylaurate

laurate

octanoate

4-hydroxybutanoate

(15Z)-tetracosenoate

linoleate

α-linolenate

stearate

palmitate

oleate

phytenate

L-α-amino-ε-keto-pimelate

carbamate

L-serine

L-tyrosine

L-glutamine

glycine

L-threonine

L-cysteine

L-histidine

L-arginine

L-lysine

L-glutamate

L-valine

L-phenylalanine

L-proline

L-isoleucine

L-tryptophan

L-alanine

L-leucine

L-methionine

D-glutamate

L,L-diaminopimelate

L-aspartyl-4-phosphate

L-ornithine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

3-phospho-L-serine

N-acetyl-L-glutamate

trans-4-hydroxy-L-proline

O-acetyl-L-homoserine

L-citrulline

L-glutamate-5-semialdehyde

L-canaline

L-homoserine

L-aspartate 4-semialdehyde

O-phospho-L-homoserine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

meso-diaminopimelate

γ-L-glutamyl-L-cysteine