an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

2-dehydro-3-deoxy-D-galactonate 6-phosphate

(R)-4-phosphopantoate

S-ribosyl-L-homocysteine

autoinducer 2

(R)-4'-phosphopantothenate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

5,6-dimethylbenzimidazole

dialurate

(R)-1-amino-2-propanol O-2-phosphate

5-oxo-L-proline

N-acetyl-D-galactosamine 6-phosphate

D-galactosamine-6-phosphate

4-hydroxy-2-nonenal

oxalosuccinate

(2S)-lactyl-2-diphospho-5'-guanosine

α-D-ribose 1,5-bisphosphate

4-amino-4-deoxychorismate

hydrogen selenide

O-acetyl-L-serine

DNA without lesion

(R)-mevalonate diphosphate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

N-methylhydantoin

tetrahydrogeranylgeranyl diphosphate

dihydrogeranylgeranyl diphosphate

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

(S)-2-amino-6-oxohexanoate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

citraconate

(2R,3S)-3-methylmalate

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

α-D-glucosamine 1-phosphate

(R)-4'-phosphopantothenoyl-L-cysteine

N-succinyl-L,L-2,6-diaminopimelate

isochorismate

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

chlorite

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

deethylsimazine

N-ethylammeline

formamide

quinolinate

β-D-ribosylnicotinate

(R)-mevalonate

(R)-5-phosphomevalonate

(S)-mandelate

(R)-mandelate

1,4-dihydroxy-2-naphthoate

isopentenyl diphosphate

4-prenylphlorisobutyrophenone

prenyl diphosphate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

thiamine phosphate

succinate semialdehyde

urea

acetyl phosphate

4-fumaryl-acetoacetate

acetoacetate

glycolate

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

5-deoxy-α-ribose 1-phosphate

hydroxypyruvate

(R)-1-aminopropan-2-ol

α-ribazole

α-ribazole 5'-phosphate

prephenate

coproporphyrinogen III

N²-succinylglutamate

orotidine 5'-phosphate

2-dehydro-3-deoxy-D-galactonate

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

3-hydroxyanthranilate

ethanolamine

formate

1-deoxy-L-glycero-tetrulose 4-phosphate

2-(α-hydroxyethyl)thiamine diphosphate

thiamine diphosphate

hydrogen peroxide

2-dehydro-3-deoxy-D-gluconate 6-phosphate

carbonic acid

3-phosphooxypyruvate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate

creatinine

salicyl alcohol

methylsalicylate

2-dehydropantoate

histidinal

histidinol

β-nicotinate D-ribonucleotide

porphobilinogen

3-dehydroshikimate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-aminolevulinate

O-ureido-L-homoserine

L-arginino-succinate

canavaninosuccinate

L-canavanine

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

D-erythro-imidazole-glycerol-phosphate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

γ-L-glutamyl 5-phosphate

imidazole acetol-phosphate

L-histidinol phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

4'-phosphopantetheine

N-(5-phosphoribosyl)-anthranilate

anthranilate

(S)-4-amino-5-oxopentanoate

oxaloacetate

(S)-2,3,4,5-tetrahydrodipicolinate

N-succinyl-2-amino-6-ketopimelate

5-enolpyruvoyl-shikimate 3-phosphate

glycerone phosphate

shikimate

shikimate 3-phosphate

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

1,4-dihydroxy-2-naphthoyl-CoA

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

preuroporphyrinogen

(S)-dihydroorotate

phosphoenolpyruvate

CO₂

carbamoyl phosphate

carboxyphosphate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-6-(D-ribitylamino)uracil

3-methyl-2-oxobutanoate

(S)-3-methyl-2-oxopentanoate

4-methyl-2-oxopentanoate

H₂O

citrate

nicotinate adenine dinucleotide

carbon monoxide

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

ammonia

enol-phenylpyruvate

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1-piperideine 6-carboxylate

(glutathion-S-yl)-4-hydroxy-2-nonenal

DNA with lesion

L-homocysteine

hydrogen cyanide

cob(I)yrinate a,c-diamide

cob(I)inamide

cob(I)alamin

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobinamide

adenosylcobyrate

adenosyl-cobinamide phosphate

adenosylcobalamin

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

cobalt-sirohydrochlorin

cobalt-factor III

cobalt-precorrin-2

cobalt-precorrin-3

protoporphyrinogen IX

uroporphyrinogen-III

uroporphyrinogen-I

siroheme

hydrogen sulfide

oxygen

2-iminosuccinate

2-iminobutanoate

2-chloroacetate

β-D-mannosyl-(C55 ω-saturated dolichyl phosphate)

sn-glycerol 1-phosphate

sn-glycerol 3-phosphate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

ω-saturated C55 dolichol phosphate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(R)-citramalate

(S)-4-hydroxymandelate

(R)-4-hydroxymandelate

(indole-3-yl)acetonitrile

1-chloro-2,4-dinitrobenzene

2,4-dinitrophenyl-S-glutathione

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

Fe³⁺

H⁺

ammonium

Cu²⁺

Fe²⁺

Zn²⁺

Pb²⁺

Hg²⁺

Cd²⁺

thiosulfate

sulfite

hydrogencarbonate

nitrate

molybdate

sulfate

hydrogensulfite

phosphonate

phosphate

triphosphate

diphosphate

chloride

(2E,6E)-farnesyl diphosphate

pristanate

glycerophosphoglycerol

glycerophosphoserine

sn-glycero-3-phosphoethanolamine

(2Z)-2-aminobut-2-enoate

agmatine

putrescine

dehydrospermidine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

methanethiol

glutathione

thiocyanate

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

L-cysteate

3-sulfopyruvate

all-trans-retinyl palmitate

D-glucono-1,5-lactone

formyl-CoA

oxalyl-CoA

(2S)-ethylmalonyl-CoA

(2R)-ethylmalonyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

3'-dephospho-CoA

succinyl-CoA

(S)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

phytenoyl-CoA

oleoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

7-hydroxylauroyl-CoA

18-hydroxystearoyl-CoA

16-hydroxypalmitoyl-CoA

18-hydroxyoleoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

octanoyl-CoA

lauroyl-CoA

decanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

tributyrin

1,2-dibutyrin

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

methyl (indol-3-yl)acetate

(indol-3-yl)acetate

nicotinate

riboflavin

all-trans-retinol

all-trans-retinal

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

pyridoxal 5'-phosphate

FAD

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADH

NADPH

NADP⁺

NAD⁺

caldariellaquinone

caldariellaquinol

demethylmenaquinol-8

glycine betaine

cyclic-AMP

1-(5-phospho-β-D-ribosyl)-AMP

XMP

GMP

1-(5-phospho-β-D-ribosyl)-ATP

IMP

adenylo-succinate

5'-deoxyadenosine

dADP

dATP

IDP

ITP

dIDP

dITP

dGDP

dGTP

ADP

GTP

GDP

ATP

AMP

xanthosine

guanosine

inosine

adenosine

cytidine

uridine

2'-deoxycytidine

2'-deoxyuridine

thymidine

dTTP

dCTP

dUTP

UTP

CTP

dCMP

dUMP

dTMP

CMP

UMP

dUDP

dTDP

dCDP

CDP

UDP

β-nicotinamide D-ribonucleotide

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

GDP-α-D-mannose

ADP-D-ribose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

thymine

uracil

adenine

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-galactose

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-glucosamine

coenzyme A

oxidized coenzyme F₄₂₀-0

MoO₂-molybdopterin cofactor

guanylyl molybdenum cofactor

(S)-1-pyrroline-5-carboxylate

precorrin-6B

precorrin-7

precorrin-8x

precorrin-5

precorrin-3B

precorrin-4

precorrin-1

precorrin-2

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

7,8-dihydroneopterin 3'-triphosphate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

orotate

4-hydroxybenzoate

salicyl-6-hydroxy-2-cyclohexene-on-oyl

6-hydroxy-2-cyclohexen-one-carboxylate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

salicylate

4-aminobenzoate

diacetyl

acetone

methylglyoxal

formaldehyde

acetaldehyde

D-glyceraldehyde

ethanol

methanol

glycerol

myo-inositol

1D-myo-inositol 1-monophosphate

1D-myo-inositol 3-monophosphate

1-(β-D ribofuranosyl)nicotinamide

keto-D-fructose

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose

D-ribulose-1,5-bisphosphate

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

D-galactonate

D-gluconate

18-hydroxystearate

16-hydroxypalmitate

18-hydroxyoleate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

geranyl diphosphate

β-carotene 15,15' epoxide

15,15'-dihydroxy-β-carotene

β-carotene

phytyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

all-trans-octaprenyl diphosphate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

phlorisovalerophenone

deoxyhumulone

deoxycohumulone

4-prenylphlorisovalerophenone

3-benzyl-3,6-dihydroxy-6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

(3E)-2-oxohex-3-enedioate

chorismate

succinate

fumarate

L-aspartate

(S)-malate

(4S)-4-hydroxy-2-oxoglutarate

α,ω-9Z-octadecenedioate

(2S,3S)-2-methylcitrate

cis-2-methylaconitate

cis-aconitate

D-threo-isocitrate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

glyoxylate

pyruvate

2-oxobutanoate

2-oxoglutarate

butanoate

octanoate

7-hydroxylaurate

laurate

decanoate

(S)-lactate

(R)-lactate

(15Z)-tetracosenoate

oleate

α-linolenate

linoleate

stearate

palmitate

phytenate

(R)-pantoate

acetate

L-kynurenine

carbamate

L-serine

L-asparagine

L-tyrosine

L-glutamine

L-threonine

glycine

L-cysteine

L-lysine

L-histidine

L-arginine

L-glutamate

L-selenocysteine

L-phenylalanine

L-proline

L-alanine

L-tryptophan

L-valine

L-isoleucine

L-leucine

L-methionine

N-carbamoylsarcosine

creatine

β-alanine

L-cystathionine

L,L-diaminopimelate

L-ornithine

L-aspartyl-4-phosphate

N-carbamoyl-L-aspartate

N-acetyl-L-aspartate

N-acetyl-L-ornithine

L-saccharopine

3-phospho-L-serine

N-acetyl-L-glutamate

trans-4-hydroxy-L-proline

3-hydroxy-L-kynurenine

O-acetyl-L-homoserine

L-citrulline

S-sulfo-L-cysteine

O-succinyl-L-homoserine

L-canaline

hypoglycin A

L-glutamate-5-semialdehyde

S-adenosyl-L-methionine

L-homoserine

O-phospho-L-homoserine

L-aspartate 4-semialdehyde

S-adenosyl-L-homocysteine

meso-diaminopimelate

hypoglycin B

L-cysteinylglycine