an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

ammonia

enol-phenylpyruvate

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

N⁵-carboxyaminoimidazole ribonucleotide

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

(2R,3S)-3-methylmalate

citraconate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

(S)-2,3,4,5-tetrahydrodipicolinate

(R)-mevalonate diphosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

acetyl phosphate

S-ribosyl-L-homocysteine

autoinducer 2

5-carboxymethyl-2-hydroxymuconate

deethylsimazine

N-ethylammeline

α-ribazole

α-ribazole 5'-phosphate

β-nicotinate D-ribonucleotide

quinolinate

thiamine phosphate

thiamine diphosphate

α-D-ribose 1,5-bisphosphate

tetrahydrogeranylgeranyl diphosphate

dihydrogeranylgeranyl diphosphate

(R)-mevalonate

(R)-5-phosphomevalonate

urea

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

hydrogenobyrinate

(R)-4'-phosphopantothenoyl-L-cysteine

1-deoxy-L-glycero-tetrulose 4-phosphate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

creatinine

3-phosphooxypyruvate

methanophenazine

dihydromethanophenazine

γ-L-glutamyl 5-phosphate

L-β-lysine

ADP-D-glycero-β-D-manno-heptose

ADP-L-glycero-β-D-manno-heptose

5-oxo-L-proline

hydrogenobyrinate a,c-diamide

isopentenyl diphosphate

prenyl diphosphate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

(2S)-lactyl-2-diphospho-5'-guanosine

α-D-glucosamine 1-phosphate

coenzyme B

CoB-CoM heterodisulfide

hexulose 6-phosphate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

glycolate

coproporphyrinogen III

N-(5-phosphoribosyl)-anthranilate

anthranilate

nicotinate adenine dinucleotide

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

pimelate

pimeloyl-CoA

carboxyphosphate

O-ureido-L-homoserine

4'-phosphopantetheine

carbon monoxide

S-adenosyl 3-(methylsulfanyl)propylamine

S-methyl-5'-thioadenosine

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-4-amino-5-oxopentanoate

5-amino-6-(D-ribitylamino)uracil

histidinal

histidinol

8-amino-7-oxononanoate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

7,8-diaminopelargonate

prephenate

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

carbamoyl phosphate

3-methyl-2-oxobutanoate

(S)-3-methyl-2-oxopentanoate

4-methyl-2-oxopentanoate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

preuroporphyrinogen

glycerone phosphate

D-erythro-imidazole-glycerol-phosphate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

selenophosphate

imidazole acetol-phosphate

L-histidinol phosphate

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

dethiobiotin

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

shikimate

3-dehydroshikimate

(S)-dihydroorotate

phosphoenolpyruvate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

5-aminolevulinate

porphobilinogen

orotidine 5'-phosphate

CO₂

oxaloacetate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

H₂

L-arginino-succinate

canavaninosuccinate

L-canavanine

H₂O

hypoxanthine

cyclic-AMP

dADP

dATP

IDP

ITP

dIDP

dITP

dGDP

dGTP

1-(5-phospho-β-D-ribosyl)-ATP

XMP

GMP

GTP

IMP

adenylo-succinate

GDP

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-AMP

AMP

ATP

ADP

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

UTP

CTP

CMP

UMP

CDP

UDP

β-nicotinamide D-ribonucleotide

dUDP

dTDP

dCDP

dUMP

dTMP

dCMP

dTTP

dCTP

dUTP

NADPH

NADH

NADP⁺

NAD⁺

GDP-α-D-mannose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

adenine

uracil

thymine

UDP-α-D-glucose

CDP-α-D-glucose

UDP-α-D-glucuronate

UDP-α-D-galacturonate

UDP-N-acetyl-α-D-glucosamine

CDP-4-dehydro-6-deoxy-α-D-glucose

adenosine

2'-deoxycytidine

2'-deoxyuridine

thymidine

tetrahydrosarcinapterin

5-methyl-tetrahydrosarcinapterin

coenzyme M

methyl-CoM

coenzyme A

oxidized coenzyme F₄₂₀-0

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

adenylyl molybdenum cofactor

bis(molybdenum cofactor)

bis(guanylyl molybdopterin) cofactor

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-formyl-tetrahydromethanopterin

tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

orotate

precorrin-7

precorrin-5

cobalt-precorrin-2

cobalt-precorrin-5A

precorrin-8x

precorrin-3A

cobalt-precorrin-5B

cobalt-precorrin-6A

precorrin-3B

precorrin-4

precorrin-6B

precorrin-6A

precorrin-1

precorrin-2

sirohydrochlorin

cobyrinate

adenosylcobalamin

6,7-dimethyl-8-(1-D-ribityl)lumazine

FAD

FMN

riboflavin

FMNH₂

reduced riboflavin

7,8-dihydroneopterin 3'-triphosphate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

4-hydroxybenzoate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

tyramine

caldariellaquinol

menaquinol-8

demethylmenaquinol-8

caldariellaquinone

diacetyl

D-glyceraldehyde

acetaldehyde

formaldehyde

(S)-lactaldehyde

ethanol

1D-myo-inositol 3-monophosphate

keto-D-fructose

β-D-fructofuranose

N-acetyl-α-D-glucosamine 1-phosphate

D-ribulose-1,5-bisphosphate

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-glucose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

2-deoxy-α-D-ribose 1-phosphate

L-fuculose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

maltotriose

maltotetraose

maltoheptaose

maltohexaose

maltopentaose

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

1-oleoyl-2-palmitoyl-phosphatidylglycerol

(2E,6E)-farnesyl diphosphate

phytyl diphosphate

di-trans,octa-cis-undecaprenol

di-trans,octa-cis-undecaprenyl phosphate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

acetate

5-chloro-5-deoxy-D-ribonate

L-α-amino-ε-keto-pimelate

carbamate

L-citrulline

L-canaline

L-aspartate 4-semialdehyde

L-homocysteine

L-homoserine

O-phospho-L-homoserine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-ornithine

meso-diaminopimelate

L-lysine

L-isoleucine

L-leucine

L-valine

L-methionine

L-alanine

L-histidine

L-serine

L-threonine

L-phenylalanine

glycine

L-tryptophan

L-tyrosine

L-aspartate

L-glutamine

L-glutamate

L-arginine

L-cysteine

creatine

(R)-β-lysine

L,L-diaminopimelate

L-aspartyl-4-phosphate

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

3-phospho-L-serine

N-acetyl-L-methionine

N-acetyl-L-glutamate

chorismate

succinate

fumarate

(S)-malate

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

pyruvate

5-chloro-4-hydroxy-2-oxopentanoate

2-oxobutanoate

2-oxoglutarate

formate

(S)-lactate

(R)-glycerate

ethylphosphate

hydrogen cyanide

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cobalt-sirohydrochlorin

cob(II)yrinate c-monoamide

Mg-protoporphyrin

cob(II)yrinate a,c-diamide

uroporphyrinogen-I

protoporphyrin IX

protoporphyrinogen IX

uroporphyrinogen-III

siroheme

oxygen

2-iminosuccinate

2-chloroacetate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(R)-citramalate

Fe³⁺

ammonium

H⁺

Ni²⁺

Mg²⁺

Co²⁺

Fe²⁺

Mo²⁺

hydrogensulfite

thiosulfate

sulfite

selenide

hydrogencarbonate

nitrate

phosphate

triphosphate

diphosphate

chloride

agmatine

dehydrospermidine

putrescine

spermidine

thiocyanate

sulfoacetaldehyde

L-cysteate

3-sulfopyruvate

(2R)-3-sulfolactate

(2R)-phospho-3-sulfolactate

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

isobutanoyl-CoA

3'-dephospho-CoA

succinyl-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

propanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

methane

pyridoxal 5'-phosphate

(R)-NADHX

(S)-NADHX