an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

ammonia

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

autoinducer 2

N-succinyl-L,L-2,6-diaminopimelate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

histidinal

1,6-anhydro-N-acetyl-β-muramate

thiamine diphosphate

mercuriphenyl acetate

dialurate

D-glycero-β-D-manno-heptose 1,7-bisphosphate

D-glycero-β-D-manno-heptose 1-phosphate

5-dehydro-2-deoxy-D-gluconate 6-phosphate

3-oxopropanoate

5-dehydro-2-deoxy-D-gluconate

selenophosphate

N⁵-carboxyaminoimidazole ribonucleotide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

N-ethylmaleimide

N-ethylsuccinimide

shikimate

(S)-dihydroorotate

orotidine 5'-phosphate

3-dehydroshikimate

D-phenylhydantoin

N-carbamoyl-D-phenylglycine

hydrogenobyrinate a,c-diamide

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

porphobilinogen

preuroporphyrinogen

(R)-1-amino-2-propanol O-2-phosphate

carbonic acid

chloramphenicol

4-imidazolone-5-propanoate

urocanate

formamide

O-acetyl-L-serine

7-carboxy-7-deazaguanine

3-hydroxypropanal

quinolinate

5-aminopentanoate

dihydrolipoate

nicotinate adenine dinucleotide

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

propanoyl phosphate

ADP-D-glycero-β-D-manno-heptose

ADP-L-glycero-β-D-manno-heptose

(R)-4'-phosphopantothenate

(2R)-2-amino-4-oxopentanoate

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

3-hydroxy-5-oxohexanoate

3-hydroxy-5- oxohexanoyl-CoA

L-β-lysine

(3S,5S)-3,5-diaminohexanoate

(S)-5-amino-3-oxohexanoate

acetoacetate

lipid IV_A

(R)-pantothenate

2-dehydropantoate

succinate semialdehyde

coenzyme B

methanophenazine

CoB-CoM heterodisulfide

dihydromethanophenazine

L-histidinol phosphate

histidinol

GMP-N-ε-(N-α-acetyl lysine methyl ester) 5'-phosphoramidate

hydrogen peroxide

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribosylamino)uracil

2-maleylacetate

lipid X

lipid A disaccharide (E. coli)

β-D-ribosylnicotinate

citrate

mesaconate

N-acetyl-D-muramate 6-phosphate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

5,6-dimethylbenzimidazole

β-nicotinate D-ribonucleotide

α-ribazole

α-ribazole 5'-phosphate

xanthine

O-ureido-L-homoserine

L-arginino-succinate

canavaninosuccinate

L-canavanine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine phosphate

2-iminoacetate

DNA without lesion

isopentenyl diphosphate

prenyl diphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

glycolate

ethanolamine

urea

(S)-mandelate

(R)-mandelate

2-C-methyl-D-erythritol 4-phosphate

(S)-2,3,4,5-tetrahydrodipicolinate

N-succinyl-2-amino-6-ketopimelate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

coproporphyrinogen III

(S)-3-methyl-2-oxopentanoate

oxaloacetate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

carboxyphosphate

hydroxyatrazine

N-isopropylammelide

ethylamine

hydrogenobyrinate

γ-L-glutamyl 5-phosphate

acetyl phosphate

3-deoxy-D-manno-octulosonate 8-phosphate

3-deoxy-α-D-manno-2-octulosonate

N-acetyl-D-galactosamine 6-phosphate

D-galactosamine-6-phosphate

N-(5-phosphoribosyl)-anthranilate

anthranilate

glycerone phosphate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

S-ribosyl-L-homocysteine

3-methyl-2-oxobutanoate

(2S)-2-isopropylmalate

butanoyl phosphate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

carbamoyl phosphate

phosphoenolpyruvate

S-methyl-5'-thioadenosine

CO₂

S-adenosyl 3-(methylsulfanyl)propylamine

H₂O

α-D-glucosamine 1-phosphate

α-D-glucosamine 6-phosphate

hydrogen cyanide

2-iminosuccinate

2-iminopropanoate

2-iminobutanoate

4-methylphenol

L-homocysteine

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

sn-glycerol 3-phosphate

DNA with lesion

ethylphosphate

adenosylcobalamin

cob(I)alamin

adenosylcobyrate

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

cobalt-precorrin-4

cobalt-precorrin-5A

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

cob(I)inamide

Mg-protoporphyrin

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

adenosylcobinamide

adenosyl-cobinamide phosphate

protoheme

protoporphyrin IX

uroporphyrinogen-III

uroporphyrinogen-I

coproporphyrinogen I

protoporphyrinogen IX

Hg⁰

oxygen

hydrogen sulfide

2-chloroacetate

β-D-mannosyl-(C55 ω-saturated dolichyl phosphate)

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

ω-saturated C55 dolichol phosphate

(2R)-2,3-dihydroxy-3-methylbutanoate

(S)-methylmalonate-semialdehyde

(S)-4-hydroxymandelate

(R)-4-hydroxymandelate

preQ₀

chloramphenicol 3-acetate

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

H⁺

K⁺

ammonium

Fe²⁺

Hg²⁺

Mg²⁺

Mo²⁺

hydrogensulfite

selenide

thiosulfate

sulfite

hydrogencarbonate

phosphate

triphosphate

diphosphate

chloride

(2E,6E)-farnesyl diphosphate

pristanate

sn-glycero-3-phosphoethanolamine

glycerophosphoglycerol

glycerophosphoserine

1-oleoyl-2-palmitoyl-phosphatidylglycerol

glycine betaine

2-aminoprop-2-enoate

(2Z)-2-aminobut-2-enoate

agmatine

putrescine

spermidine

γ-L-glutamyl-[(S)-allyl]-L-cysteine

S-allyl-L-cysteine

γ-L-glutamyl-(S)-methyl-L-cysteine

γ-L-glutamyl-(S)-trans-1-propenyl-L-cysteine

S-trans-1-propenyl-L-cysteine

thiocyanate

glutathione

methanethiol

4-methyl-5-(2-phosphooxyethyl)thiazole

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

coenzyme M

(R)-S-lactoylglutathione

cis-dienelactone

trans-dienelactone

linoleoyl-CoA

α-linolenoyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

CoA-disulfide

3'-dephospho-CoA

(S)-3-aminobutanoyl-CoA

4-hydroxybutanoyl-CoA

succinyl-CoA

2-methylacetoacetyl-CoA

isobutanoyl-CoA

malonyl-CoA

acetyl-CoA

crotonyl-CoA

phytenoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

7-hydroxylauroyl-CoA

18-hydroxystearoyl-CoA

16-hydroxypalmitoyl-CoA

18-hydroxyoleoyl-CoA

(Z)-15-tetracosenoyl-CoA

pentanoyl-CoA

butanoyl-CoA

propanoyl-CoA

decanoyl-CoA

lauroyl-CoA

octanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

hexadecanedioyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

thiamine

nicotinate

riboflavin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

FAD

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

guanosine 2',3'-cyclic monophosphate

adenosine 2',3'-cyclic monophosphate

pppGpp

adenosine 3'-monophosphate

guanosine 3'-monophosphate

adenylo-succinate

ppGpp

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

2'-deoxyadenosine

2'-deoxyinosine

2'-deoxyguanosine

dGMP

XMP

dADP

dATP

IDP

ITP

dIDP

dITP

dGDP

dGTP

5'-deoxyadenosine

hypoxanthine

IMP

GMP

ADP

GTP

GDP

ATP

AMP

xanthosine

guanosine

inosine

adenosine

cytidine

uridine

2'-deoxycytidine

2'-deoxyuridine

thymidine

cytidine 2',3'-cyclic monophosphate

uridine 2'3'-cyclic monophosphate

cyclic di-3',5'-guanylate

dTTP

dCTP

dUTP

UTP

CTP

dCMP

dUMP

dTMP

CMP

UMP

dTDP

dCDP

dUDP

UDP

CDP

β-nicotinamide D-ribonucleotide

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

uridine 3'-monophosphate

cytidine-3'-monophosphate

GDP-α-D-mannose

ADP-α-D-glucose

preQ₁

uracil

thymine

guanine

adenine

CMP-3-deoxy-β-D-manno-octulosonate

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-α-D-galactose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

dTDP-3-dehydro-6-deoxy-α-D-galactopyranose

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

(R)-lipoate

coenzyme A

MoO₂-molybdopterin cofactor

thio-molybdenum cofactor

(S)-1-pyrroline-5-carboxylate

precorrin-1

precorrin-2

precorrin-3A

precorrin-6B

precorrin-7

precorrin-8x

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

7,8-dihydroneopterin 3'-triphosphate

6-carboxy-5,6,7,8-tetrahydropterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

orotate

benzene

urate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

phenol

diacetyl

methylglyoxal

butan-1-al

acetaldehyde

D-glyceraldehyde

α-D-ribofuranose

α-D-galactopyranose

β-D-galactopyranose

ethanol

butan-1-ol

glycerol

1D-chiro-inositol

scyllo-inositol

myo-inositol

1-keto-D-chiro-inositol

3D-(3,5/4)-trihydroxycyclohexane-1,2-dione

scyllo-inosose

1-(β-D ribofuranosyl)nicotinamide

heptosyl-Kdo₂-lipid A

(heptosyl)₂-Kdo₂-lipid A

α-Kdo-(2→6)-lipid IV_A

maltotriose

maltotetraose

maltoheptaose

maltohexaose

maltopentaose

N-acetyl-α-D-muramoyl-L-alanine(1-)

N-acetylmuramate

N-acetyl-α-D-glucosamine 1-phosphate

N-acetyl-β-D-glucosamine

β-D-fructofuranose

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

1-O-acetyl-α-maltose

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan dimer with pentapeptide stems (meso-diaminopimelate containing)

a peptidoglycan dimer with pentapeptide stem (meso-diaminopimelate containing)

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

aldehydo-D-arabinose 5-phosphate

D-arabinofuranose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

β-D-ribose 5-phosphate

α-D-ribose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

α-D-galactose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

18-hydroxystearate

16-hydroxypalmitate

18-hydroxyoleate

1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate

1-(18-hydroxyoleoyl)-sn-glycrol 3-phosphate

1-oleoyl-sn-glycerol 3-phosphate

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

geranyl diphosphate

trans,octacis-decaprenyl phosphate

di-trans,octa-cis-undecaprenyl phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

chorismate

succinate

L-aspartate

fumarate

(S)-malate

α,ω-9Z-octadecenedioate

pyruvate

glyoxylate

2-oxoglutarate

2-oxobutanoate

acetate

formate

propanoate

(R)-lactate

pentanoate

butanoate

decanoate

7-hydroxylaurate

laurate

octanoate

4-hydroxybutanoate

(15Z)-tetracosenoate

linoleate

α-linolenate

stearate

palmitate

oleate

phytenate

(R)-pantoate

5-deoxy-D-glucuronate

L-α-amino-ε-keto-pimelate

carbamate

L-serine

L-asparagine

L-threonine

L-tyrosine

L-glutamine

glycine

L-cysteine

L-histidine

L-arginine

L-lysine

L-glutamate

L-alanine

L-leucine

L-valine

L-tryptophan

L-isoleucine

L-proline

L-methionine

β-glutamate

(R)-β-lysine

β-alanine

D-glutamate

D-ornithine

D-proline

D-aspartate

D-alanine

L-isoglutamine

L,L-diaminopimelate

L-cystathionine

L-aspartyl-4-phosphate

L-ornithine

N-carbamoyl-L-aspartate

formyl-L-isoglutamine

N-formimino-L-glutamate

D-nopaline

S-sulfanyl-L-cysteine

L-threonine 3-O-phosphate

S-methyl-L-cysteine

(2S, 3S)-3-methylaspartate

trans-4-hydroxy-L-proline

N-α-acetyl lysine methyl ester

O-acetyl-L-homoserine

L-citrulline

O-phospho-L-homoserine

L-canaline

L-homoserine

L-cystine

L-aspartate 4-semialdehyde

L-glutamate-5-semialdehyde

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

meso-diaminopimelate

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

D-alanyl-D-alanine

γ-L-glutamyl-L-cysteine

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine