an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

N-acetylglutamyl-phosphate

orotidine 5'-phosphate

5-amino-6-(D-ribitylamino)uracil

5-phospho-β-D-ribosylamine

3-methyl-2-oxobutanoate

CO₂

H₂O

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

glycerone phosphate

ammonia

enol-phenylpyruvate

1,2-dihydro-β-NADP

(S)-dihydroorotate

(2S)-2-isopropyl-3-oxosuccinate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

acetyl phosphate

(R)-mevalonate diphosphate

(S)-2,3,4,5-tetrahydrodipicolinate

(R)-5-phosphomevalonate

5-(methylsulfanyl)-ribulose 1-phosphate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

quinolinate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

carbonic acid

5-methylcytosine

anthranilate

nicotinate adenine dinucleotide

deethylsimazine

N-ethylammeline

hydrogenobyrinate a,c-diamide

4-methyl-2-oxopentanoate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

N¹-(5-phospho-β-D-ribosyl)glycinamide

formate

N⁵-carboxyaminoimidazole ribonucleotide

1-deoxy-L-glycero-tetrulose 4-phosphate

oxalosuccinate

D-erythro-imidazole-glycerol-phosphate

hexulose 6-phosphate

prephenate

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

7-carboxy-7-deazaguanine

isopentenyl diphosphate

4-prenylphlorisobutyrophenone

prenyl diphosphate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

2-phosphoglycolate

glycolate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine phosphate

3-phosphooxypyruvate

citrate

preuroporphyrinogen

N-acetyl-L-glutamate 5-semialdehyde

chloramphenicol

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

shikimate

L-selenocystathionine

coproporphyrinogen III

3-hydroxypropanoate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

4-aminobutanoate

(R)-mevalonate

3-dehydroquinate

3-dehydroshikimate

O-acetyl-L-serine

coenzyme B

methanophenazine

CoB-CoM heterodisulfide

dihydromethanophenazine

DNA without lesion

creatinine

hydrogen peroxide

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

porphobilinogen

Coα-[α-(5-hydroxybenzimidazolyl)]-Coβ-methylcobamide

phosphoenolpyruvate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

histidinal

histidinol

hydrogenobyrinate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

propan-2-ol

(2S)-lactyl-2-diphospho-5'-guanosine

carbon monoxide

imidazole acetol-phosphate

L-histidinol phosphate

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

H₂

N-(5-phosphoribosyl)-anthranilate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

2-C-methyl-D-erythritol 4-phosphate

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

L-arginino-succinate

O-ureido-L-homoserine

canavaninosuccinate

oxaloacetate

carbamoyl phosphate

carboxyphosphate

β-D-mannosyl-(C55 ω-saturated dolichyl phosphate)

sn-glycerol 1-phosphate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

ω-saturated C55 dolichol phosphate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(S)-citramalate

preQ₀

chloramphenicol 3-acetate

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

molybdate

sulfite

hydrogencarbonate

phosphate

diphosphate

chloride

H⁺

ammonium

Ni²⁺

Co²⁺

Fe²⁺

Mg²⁺

(2E,6E)-farnesyl diphosphate

(2Z)-2-aminobut-2-enoate

2-iminopropanoate

2-aminoprop-2-enoate

agmatine

dehydrospermidine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

S-(hydroxymethyl)glutathione

methanethiol

glutathione

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

sulfoacetaldehyde

L-cysteate

3-sulfopyruvate

coenzyme M

(2R)-3-sulfolactate

(2R)-phospho-3-sulfolactate

(R)-S-lactoylglutathione

2-methylacetoacetyl-CoA

acetyl-CoA

isobutanoyl-CoA

phenylacetyl-CoA

3-hydroxypropanoyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

3'-dephospho-CoA

succinyl-CoA

propanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

tributyrin

1,2-dibutyrin

methane

phenylacetate

riboflavin

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

FAD

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

caldariellaquinone

caldariellaquinol

glycine betaine

ADP

ATP

XMP

GMP

AMP

cyclic-AMP

hypoxanthine

dGDP

dGTP

dIDP

dITP

IDP

ITP

dADP

dATP

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

IMP

adenylo-succinate

5'-deoxyadenosine

GTP

GDP

5-fluorocytosine

5-fluorouracil

xanthosine

inosine

adenosine

uridine

cytidine

dTTP

dUTP

dCTP

UTP

CTP

dUMP

dTMP

dCMP

UMP

CMP

dTDP

dUDP

dCDP

CDP

UDP

β-nicotinamide D-ribonucleotide

GDP-α-D-mannose

GDP-4-dehydro-α-D-rhamnose

cytosine

uracil

thymine

adenine

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-galactofuranose

UDP-α-D-galactose

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

coenzyme A

5-methyl-tetrahydrosarcinapterin

tetrahydrosarcinapterin

methyl-CoM

oxidized coenzyme F₄₂₀-0

(S)-1-pyrroline-5-carboxylate

precorrin-1

precorrin-2

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-2

cobalt-precorrin-5B

cobalt-precorrin-6A

precorrin-8x

cobalt-precorrin-4

cobalt-precorrin-5A

cobyrinate

sirohydrochlorin

Coα-[α-(5-hydroxybenzimidazolyl)]-cobamide

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin

7,8-dihydromonapterin

6-(hydroxymethyl)-7,8-dihydropterin

orotate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

diacetyl

acetone

methylglyoxal

glycolaldehyde

formaldehyde

acetaldehyde

(S)-lactaldehyde

D-glyceraldehyde

α-D-ribofuranose

ethanol

methanol

D-ribitol 5-phosphate

1D-myo-inositol 3-monophosphate

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-glucose 6-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

β-D-ribose 5-phosphate

α-D-ribose 5-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

daunorubicin

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

saturated archaetidylserine

saturated archaetidylethanolamine

unsaturated archaetidylserine

unsaturated archaetidylethanolamine

geranyl diphosphate

geranylgeranyl diphosphate

phlorisovalerophenone

deoxyhumulone

deoxycohumulone

4-prenylphlorisovalerophenone

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

chorismate

succinate

fumarate

L-aspartate

(S)-malate

D-threo-isocitrate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

2-oxobutanoate

pyruvate

2-oxoglutarate

butanoate

(S)-lactate

acetate

L-α-amino-ε-keto-pimelate

carbamate

L-serine

L-threonine

L-glutamine

L-cysteine

glycine

L-tyrosine

L-lysine

L-arginine

L-histidine

L-glutamate

L-leucine

L-valine

L-isoleucine

L-methionine

L-proline

L-phenylalanine

L-tryptophan

creatine

D-glutamate

L,L-diaminopimelate

L-cystathionine

L-ornithine

L-aspartyl-4-phosphate

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

S-sulfanyl-L-cysteine

seleno-L-homocysteine

3-phospho-L-serine

N-acetyl-L-glutamate

trans-4-hydroxy-L-proline

O-acetyl-L-homoserine

L-citrulline

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

O-phospho-L-homoserine

L-homocysteine

L-homoserine

L-aspartate 4-semialdehyde

L-glutamate-5-semialdehyde

L-cystine

L-canaline

meso-diaminopimelate

DNA with lesion

N₂

cobalt-factor III

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobalt-sirohydrochlorin

Mg-protoporphyrin

uroporphyrinogen-III

uroporphyrinogen-I

protoporphyrinogen IX

protoporphyrin IX

siroheme

hydrogen sulfide

oxygen

2-iminobutanoate

2-iminosuccinate