an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

2-(sulfomethyl)thiazolidine-4-carboxylate

sulfoethylcysteine

(R)-mevalonate diphosphate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

citraconate

(2R,3S)-3-methylmalate

4-amino-2-methyl-5-pyrimidinemethanol

autoinducer 2

S-ribosyl-L-homocysteine

α-D-galacturonate 1-phosphate

L-gulono-1,4-lactone

L-xylo-hex-3-ulono-1,4-lactone

carbamoyl phosphate

L-histidinol phosphate

imidazole acetol-phosphate

preuroporphyrinogen

porphobilinogen

oxaloacetate

prenyl diphosphate

isopentenyl diphosphate

dethiobiotin

CO₂

7,8-diaminopelargonate

H₂O

pimeloyl-CoA

8-amino-7-oxononanoate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

orotidine 5'-phosphate

urea

anthranilate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-enolpyruvoyl-shikimate 3-phosphate

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

H₂

(R)-5-phosphomevalonate

(R)-mevalonate

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

α-ribazole 5'-phosphate

β-nicotinate D-ribonucleotide

5,6-dimethylbenzimidazole

histidinol

histidinal

3-dehydroshikimate

3-dehydroquinate

1-deoxy-L-glycero-tetrulose 4-phosphate

N-succinyl-L,L-2,6-diaminopimelate

3-phosphooxypyruvate

dialurate

CoB-CoM heterodisulfide

coenzyme B

L-arginino-succinate

canavaninosuccinate

O-ureido-L-homoserine

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

phosphoenolpyruvate

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

N-(5-phosphoribosyl)-anthranilate

5-amino-6-(D-ribitylamino)uracil

shikimate

L-quinate

thiamine diphosphate

thiamine phosphate

shikimate 3-phosphate

(S)-2,3,4,5-tetrahydrodipicolinate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

(S)-3-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

glycolate

2-phosphoglycolate

4'-phosphopantetheine

(R)-4'-phosphopantothenoyl-L-cysteine

(R)-4'-phosphopantothenate

dihydromethanophenazine

methanophenazine

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

4-(β-D-ribofuranosyl)-N-succinylaminobenzene 5'-phosphate

crotonate

cyclohex-1,5-diene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

3-hydroxypimeloyl-CoA

3-oxopimeloyl-CoA

cyclohexane-1-carboxylate

cyclohexane-1-carbonyl-CoA

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

carbonic acid

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

glycerone phosphate

ADP-L-glycero-β-D-manno-heptose

ADP-D-glycero-β-D-manno-heptose

prephenate

carbon monoxide

S-adenosyl 3-(methylsulfanyl)propylamine

(R)-2,3-dihydroxy-3-methylpentanoate

nicotinate adenine dinucleotide

quinolinate

(2S)-2-isopropylmalate

2-isopropylmaleate

L-dehydro-ascorbate

ammonia

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

dehydroascorbate (bicyclic form)

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

2,3-dioxo-L-gulonate

2-carboxy-L-xylonolactone

2-carboxy-L-threo-pentonate

3-deoxy-D-arabino-heptulosonate 7-phosphate

L-canavanine

pimelate

(S)-dihydroorotate

hydrogenobyrinate a,c-diamide

arsenite

L-β-lysine

(S)-ureidoglycolate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

D-erythro-imidazole-glycerol-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-oxo-L-proline

3'-phosphoadenylyl-sulfate

hexulose 6-phosphate

2-oxoadipate

S-Inosyl-L-homocysteine

hydrogenobyrinate

creatinine

selenophosphate

3-phosphonopyruvate

coproporphyrinogen III

γ-L-glutamyl 5-phosphate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

3-ureidopropanoate

oxalate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

itaconate

α-ribazole

S-methyl-5'-thioadenosine

(2S)-lactyl-2-diphospho-5'-guanosine

4-acetamidobutanoate

4-acetamidobutanal

N²-succinylglutamate

N²-succinyl-L-glutamate 5-semialdehyde

(L-threonylcarbamoyl)adenylate

5-deoxy-α-ribose 1-phosphate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(R)-1-amino-2-propanol O-2-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl 5-phosphate]-D-ribitol

hydrogen peroxide

cis-(homo)₂aconitate

2-oxopimelate

cis-(homo)₃aconitate

2-oxosuberate

7-oxoheptanoate

7-mercaptoheptanoate

7-mercaptoheptanoylthreonine

(2E,6E)-farnesyl diphosphate

sulfate

sulfite

selenate

selenide

thiosulfate

hydrogensulfite

hydrogencarbonate

sulfide(2-)

molybdate

phosphate

diphosphate

triphosphate

Fe³⁺

ammonium

H⁺

Fe²⁺

Mg²⁺

Co²⁺

(2R)-phospho-3-sulfolactate

coenzyme M

sulfoacetaldehyde

3-sulfopyruvate

(2R)-3-sulfolactate

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

thiocyanate

4-nitrophenol

4-nitrophenyl phosphate

monodehydroascorbate radical

nitric oxide

(S)-2-hydroxyglutarate

2-octaprenylphenol

(R)-citramalate

(S)-citramalate

(2R)-2,3-dihydroxy-3-methylbutanoate

(2S)-2-phospholactate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 1-phosphate

hydrogen sulfide

oxygen

uroporphyrinogen-I

Mg-protoporphyrin

protoporphyrin IX

uroporphyrinogen-III

protoporphyrinogen IX

siroheme

N₂

hydrogen cyanide

adenosylcobalamin

cob(II)yrinate a,c-diamide

adenosylcobalamin 5'-phosphate

adenosylcobinamide-GDP

adenosylcobyrate

adenosyl-cob(III)yrinate a,c-diamide

cobyrinate

cob(II)yrinate c-monoamide

cobalt-precorrin-5B

cobalt-precorrin-5A

cobalt-precorrin-4

cobalt-precorrin-6A

cobalt-precorrin-6B

cobalt-precorrin-8

cobalt-precorrin-7

cobalt-sirohydrochlorin

cobalt-precorrin-3

cobalt-factor III

cob(I)yrinate a,c-diamide

adenosyl-cobinamide phosphate

phosphonoacetaldehyde

ethylphosphate

L-homocysteine

L-α-amino-ε-keto-pimelate

L-2-aminoadipate

L-cysteine

L-glutamine

L-tyrosine

L-serine

L-asparagine

glycine

L-threonine

L-aspartate

L-glutamate

L-lysine

L-histidine

L-arginine

N^ω-hydroxy-L-arginine

L-alanine

L-leucine

creatine

β-alanine

L-valine

L-tryptophan

L-isoleucine

L-methionine

L-aspartyl-4-phosphate

L,L-diaminopimelate

L-ornithine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

L-citrulline

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-aspartate 4-semialdehyde

O-phospho-L-homoserine

L-homoserine

meso-diaminopimelate

L-selenomethionine

seleno-L-homocysteine

3-phospho-L-serine

N-carbamoylglycine

N-acetyl-L-glutamate

2-iminosuccinate

2'-deoxyguanosine

2'-deoxyadenosine

dGMP

dAMP

AMP

ATP

ADP

5'-deoxyadenosine

dATP

GTP

dGTP

adenylo-succinate

GDP

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

GMP

XMP

IMP

hypoxanthine

dADP

dGDP

ITP

IDP

dITP

dIDP

cyclic-AMP

dIMP

XTP

ADP-D-ribose

ADP ribose 1''-phosphate

ADP ribose 1'',2''-cyclic phosphate

GDP-4-dehydro-α-D-rhamnose

GDP-α-D-mannose

NADP⁺

NAD⁺

NADPH

NADH

5,6-dihydrothymine

5,6-dihydrouracil

dTDP-4-dehydro-β-L-rhamnose

dTDP-β-L-rhamnose

dTDP-α-D-glucose

UDP-α-D-galacturonate

UDP-α-D-glucose

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-glucosamine

adenine

uracil

thymine

dTMP

dCMP

dUMP

dTDP

dCDP

dUDP

dCTP

dUTP

dTTP

CDP

UDP

β-nicotinamide D-ribonucleotide

reduced β-nicotinamide D-ribonucleotide

CTP

UTP

UMP

CMP

2'-deoxyuridine

2'-deoxycytidine

thymidine

adenosine

uridine

cytidine

aldehydo-L-galactonate

L-gulonate

maltotriose

sucrose

maltotetraose

maltopentaose

maltohexaose

maltoheptaose

aldehydo-D-galacturonate

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

α-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

β-D-fructose 1,6-bisphosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

sucrose 6^F-phosphate

D-ribulose-1,5-bisphosphate

β-D-fructofuranose

D-glyceraldehyde

glycolaldehyde

β-D-glucopyranose

α-D-glucopyranose

salicylaldehyde

(3S)-linalool

(3R)-linalool

geranyl diphosphate

apo-4'-lycopenal

apo-4'-lycopenoate

phytyl diphosphate

unsaturated CDP-archaeol

saturated CDP-archaeol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

di-trans,octa-cis-undecaprenyl diphosphate

geranylgeranyl diphosphate

all-trans-octaprenyl diphosphate

3-octaprenyl-4-hydroxybenzoate

ethanol

myo-inositol

1D-myo-inositol 3-monophosphate

1D-myo-inositol 4-monophosphate

1D-myo-inositol 5-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 1-monophosphate

1D-myo-inositol 2-monophosphate

benzaldehyde

(R)-lactaldehyde

acetaldehyde

1-octanal

diacetyl

menadione

octanoate

acetate

pyruvate

formate

propanoate

(R)-lactate

(S)-lactate

(-)threo-iso(homo)₂citrate

(-)threo-iso(homo)₃citrate

(R)-2-hydroxybutanoate

(1R,2S)-homoisocitrate

(2R)-homocitrate

dihomocitrate

trihomocitrate

cis-homoaconitate

3-(carbamoylamino)-2-methylpropanoate

chorismate

fumarate

succinate

(S)-malate

(R)-malate

2-oxoglutarate

2-oxobutanoate

glyoxylate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

salicylate

4-aminobenzoate

benzoate

orotate

aldehydo-D-glucuronate

4-hydroxybenzoate

menadiol

demethylmenaquinol-8

menaquinol-8

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

tyramine

(indole-3-yl)acetonitrile

tetrahydromethanopterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

molybdopterin adenine dinucleotide

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

7,8-dihydroneopterin 3'-triphosphate

molybdopterin

cyclic pyranopterin phosphate

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol 5'-phosphate

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

7,8-dihydropteroate

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

5-methyltetrahydropteroyl tri-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

N⁵-methyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

7,8-dihydromethanopterin

demethylated 7,8-dihydromethanopterin

7,8-dihydrofolate monoglutamate

FAD

riboflavin

FMN

FMNH₂

reduced riboflavin

6,7-dimethyl-8-(1-D-ribityl)lumazine

hydantoin

sirohydrochlorin

precorrin-5

precorrin-4

precorrin-6A

precorrin-6B

precorrin-3B

precorrin-2

precorrin-1

precorrin-8x

precorrin-7

precorrin-3A

nicotinate

L-ascorbate

coenzyme A

methyl-CoM

oxidized coenzyme F₄₂₀-0

(R)-NADHX

(S)-NADHX

glutaryl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

succinyl-CoA

3'-dephospho-CoA

acetyl-CoA

malonyl-CoA

isobutanoyl-CoA

(E)-glutaconyl-CoA

(R)-2-hydroxyglutaryl-CoA

itaconyl-CoA

acetoacetyl-CoA

propanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

crotonyl-CoA

L-galactono-1,4-lactone

(indol-3-yl)acetate

methane

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

agmatine

putrescine

spermidine

dehydrospermidine