an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

L-dehydro-ascorbate

α-D-galacturonate 1-phosphate

L-xylo-hex-3-ulono-1,4-lactone

L-gulono-1,4-lactone

S-ribosyl-L-homocysteine

autoinducer 2

(R)-mevalonate diphosphate

4-amino-2-methyl-5-pyrimidinemethanol

(2R,3S)-3-methylmalate

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl 5-phosphate]-D-ribitol

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol

dialurate

ammonia

N⁵-carboxyaminoimidazole ribonucleotide

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

acetyl phosphate

5,6-dimethylbenzimidazole

(R)-1-amino-2-propanol O-2-phosphate

(2S)-2-isopropylmalate

2-isopropylmaleate

(L-threonylcarbamoyl)adenylate

1-deoxy-L-glycero-tetrulose 4-phosphate

hydroxylamine

α-ribazole

α-ribazole 5'-phosphate

γ-L-glutamyl 5-phosphate

(2S)-lactyl-2-diphospho-5'-guanosine

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

selenophosphate

creatinine

4-amino-4-deoxychorismate

coproporphyrinogen III

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

hydrogenobyrinate

shikimate

hydrogen peroxide

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

porphobilinogen

citraconate

N¹-(5-phospho-β-D-ribosyl)glycinamide

hydroxypyruvate

arsenite

L-canavanine

carbon monoxide

(R)-2,3-dihydroxy-3-methylpentanoate

isopentenyl diphosphate

prenyl diphosphate

hydrogenobyrinate a,c-diamide

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

α-D-glucosamine 1-phosphate

N-acetyl-L-glutamate 5-semialdehyde

O-ureido-L-homoserine

canavaninosuccinate

L-arginino-succinate

S-Inosyl-L-homocysteine

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

N-(5-phosphoribosyl)-anthranilate

shikimate 3-phosphate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

S-adenosyl 3-(methylsulfanyl)propylamine

(S)-ureidoglycolate

(S)-2,3,4,5-tetrahydrodipicolinate

hexulose 6-phosphate

(S)-dihydroorotate

histidinal

2-oxoadipate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

7,8-diaminopelargonate

nicotinate adenine dinucleotide

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

preuroporphyrinogen

orotidine 5'-phosphate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

3α,7α-dihydroxy-24-oxo-5β-cholestanoyl CoA

prephenate

pimelate

carbamoyl phosphate

3-dehydroshikimate

2-carboxy-L-threo-pentonate

2-carboxy-L-xylonolactone

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

2,3-dioxo-L-gulonate

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

dehydroascorbate (bicyclic form)

pyruvic oxime

4-(β-D-ribofuranosyl)-N-succinylaminobenzene 5'-phosphate

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

methanophenazine

dihydromethanophenazine

L-histidinol phosphate

histidinol

N-acetylglutamyl-phosphate

urea

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

5-phospho-β-D-ribosylamine

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

N-succinyl-L,L-2,6-diaminopimelate

(R)-5-phosphomevalonate

5-amino-6-(D-ribitylamino)uracil

oxaloacetate

dethiobiotin

2-phosphoglycolate

glycolate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

3-methyl-2-oxobutanoate

(S)-3-methyl-2-oxopentanoate

coenzyme B

CoB-CoM heterodisulfide

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

anthranilate

H₂

phosphoenolpyruvate

5-enolpyruvoyl-shikimate 3-phosphate

carbonic acid

β-nicotinate D-ribonucleotide

quinolinate

(2S)-2-isopropyl-3-oxosuccinate

(2R,3S)-3-isopropylmalate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

ADP-D-glycero-β-D-manno-heptose

ADP-L-glycero-β-D-manno-heptose

(R)-mevalonate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

glycerone phosphate

8-amino-7-oxononanoate

CO₂

pimeloyl-CoA

3-phosphooxypyruvate

thiamine phosphate

thiamine diphosphate

H₂O

(2E,6E)-farnesyl diphosphate

agmatine

dehydrospermidine

spermidine

putrescine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

1-oleoyl-2-palmitoyl-phosphatidylglycerol

2-chloroacetate

5-amino-4-imidazolecarboxyamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

methane

3,24-dioxocholest-4-en-26-oyl-CoA

3-oxochol-4-en-24-oyl-CoA

L-galactono-1,4-lactone

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

CoA-disulfide

3'-dephospho-CoA

succinyl-CoA

chenodeoxycholoyl-CoA

3α,7α,12α-trihydroxy-24-oxo-5-β-cholestanoyl CoA

choloyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

acetyl-CoA

propanoyl-CoA

acetoacetyl-CoA

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

menaquinol-8

demethylmenaquinol-8

tetrahydrosarcinapterin

5-methyl-tetrahydrosarcinapterin

molybdopterin

coenzyme M

methyl-CoM

coenzyme A

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

oxidized coenzyme F₄₂₀-0

7,8-dihydrofolate monoglutamate

demethylated 7,8-dihydromethanopterin

7,8-dihydromethanopterin

5,10-methylene-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5,6,7,8-tetrahydrofolate

tetrahydropteroyl tri-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

L-ascorbate

nicotinate

riboflavin

pyridoxamine 5'-phosphate

pyridoxal 5'-phosphate

menadione

adenine

2'-deoxyadenosine

2'-deoxyguanosine

adenosine

hypoxanthine

dAMP

dGMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

GMP

IMP

XMP

AMP

ITP

GTP

ATP

uracil

dTMP

dUMP

dCMP

orotate

dUDP

dTDP

dCDP

dUTP

dCTP

UTP

UDP

CTP

CDP

dTTP

cytidine

uridine

2'-deoxycytidine

2'-deoxyuridine

thymidine

thymine

UMP

CMP

UDP-α-D-galacturonate

UDP-α-D-galactofuranose

UDP-β-L-iduronate

UDP-α-D-galactose

UDP-α-D-glucuronate

UDP-α-D-glucose

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-glucosamine

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

dTDP-α-D-glucose

adenosylcobalamin

precorrin-3A

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-4

cobalt-precorrin-5A

cobalt-precorrin-5B

cobalt-precorrin-6A

precorrin-7

precorrin-8x

cobalt-precorrin-2

cobalt-precorrin-3

precorrin-3B

precorrin-1

precorrin-2

precorrin-6B

precorrin-6A

precorrin-4

precorrin-5

sirohydrochlorin

cobyrinate

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

molybdopterin adenine dinucleotide

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol

cyclic pyranopterin phosphate

7,8-dihydroneopterin 3'-triphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

4-hydroxybenzoate

4-aminobenzoate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

menadiol

4-nitrophenol

L-α-amino-ε-keto-pimelate

L-cysteine

L-tyrosine

L-asparagine

glycine

L-threonine

L-glutamine

L-serine

N^ω-hydroxy-L-arginine

L-arginine

L-histidine

L-lysine

L-glutamate

L-aspartate

L-phenylalanine

L-tryptophan

seleno-L-homocysteine

L-selenomethionine

L-aspartyl-4-phosphate

N-acetyl-L-ornithine

N-acetyl-L-methionine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

3-phospho-L-serine

L-citrulline

L-homoserine

L-ornithine

O-phospho-L-homoserine

L-homocysteine

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

meso-diaminopimelate

L-methionine

L-valine

L-leucine

L-isoleucine

L-alanine

L,L-diaminopimelate

creatine

acetate

aldehydo-D-glucuronate

aldehydo-D-galacturonate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

pyruvate

glyoxylate

2-oxobutanoate

2-oxoglutarate

chorismate

succinate

fumarate

(R)-malate

(S)-malate

(1R,2S)-homoisocitrate

(R)-2-hydroxybutanoate

(S)-lactate

(S)-2-hydroxyglutarate

(R)-glycerate

formate

propanoate

diacetyl

glycolaldehyde

D-glyceraldehyde

α-D-glucopyranose

β-D-glucopyranose

acetaldehyde

formaldehyde

(S)-lactaldehyde

myo-inositol

1D-myo-inositol 2-monophosphate

1D-myo-inositol 1-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 5-monophosphate

1D-myo-inositol 4-monophosphate

1D-myo-inositol 3-monophosphate

(3R)-linalool

(3S)-linalool

saturated archaetidylserine

saturated archaetidylethanolamine

unsaturated archaetidylserine

unsaturated archaetidylethanolamine

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

geranyl diphosphate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

phytyl diphosphate

3-octaprenyl-4-hydroxybenzoate

iron(III) dicitrate

ferric-enterobactin complex

keto-D-fructose

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose

D-ribulose-1,5-bisphosphate

sucrose 6^F-phosphate

GDP-α-D-mannose

GDP-4-dehydro-α-D-rhamnose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

L-fuculose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

maltotriose

maltotetraose

maltoheptaose

maltohexaose

maltopentaose

sucrose

aldehydo-L-galactonate

L-gulonate

cyclic-AMP

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

5'-deoxyadenosine

adenylo-succinate

β-nicotinamide D-ribonucleotide

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

2-iminosuccinate

adenosyl-cobinamide phosphate

cob(I)yrinate a,c-diamide

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

cob(II)yrinate c-monoamide

cobalt-sirohydrochlorin

cobalt-factor III

cob(II)yrinate a,c-diamide

Mg-protoporphyrin

N₂

protoporphyrinogen IX

protoporphyrin IX

uroporphyrinogen-III

uroporphyrinogen-I

siroheme

oxygen

sn-glycerol 1-phosphate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(R)-citramalate

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol

nitric oxide

monodehydroascorbate radical

4-nitrophenyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

taurine

sulfoacetaldehyde

L-cysteate

3-sulfopyruvate

(2R)-3-sulfolactate

(2R)-phospho-3-sulfolactate

sulfate

sulfite

selenate

selenide

thiosulfate

nitrite

nitrate

hydrogencarbonate

molybdate

chloride

phosphonate

phosphate

triphosphate

diphosphate

Fe³⁺

ammonium

H⁺

Cu²⁺

Fe²⁺

Ca²⁺

Mg²⁺

Co²⁺