an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

L-dehydro-ascorbate

α-D-galacturonate 1-phosphate

L-xylo-hex-3-ulono-1,4-lactone

L-gulono-1,4-lactone

4-amino-2-methyl-5-pyrimidinemethanol

ammonia

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

S-ribosyl-L-homocysteine

autoinducer 2

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl 5-phosphate]-D-ribitol

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol

2-carboxy-L-threo-pentonate

2-carboxy-L-xylonolactone

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

cyclohexane-1-carbonyl-CoA

2,3-dioxo-L-gulonate

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

acetyl phosphate

(2R,3S)-3-methylmalate

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

dehydroascorbate (bicyclic form)

pyruvic oxime

1-piperideine 6-carboxylate

(R)-mevalonate diphosphate

(S)-2,3,4,5-tetrahydrodipicolinate

N⁵-carboxyaminoimidazole ribonucleotide

5,6-dimethylbenzimidazole

dialurate

(R)-1-amino-2-propanol O-2-phosphate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

L-canavanine

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

ADP-D-glycero-β-D-manno-heptose

ADP-L-glycero-β-D-manno-heptose

urea

γ-L-glutamyl 5-phosphate

(R)-5-phosphomevalonate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

selenophosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

S-methyl-5'-thioadenosine

orotidine 5'-phosphate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

oxalate

N²-succinyl-L-glutamate 5-semialdehyde

N²-succinylglutamate

4-acetamidobutanal

4-acetamidobutanoate

creatinine

7,8-didemethyl-8-hydroxy-5-deazariboflavin

(2S)-lactyl-2-diphospho-5'-guanosine

L-β-lysine

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

(S)-2-amino-6-oxohexanoate

L-histidinol phosphate

α-ribazole

α-ribazole 5'-phosphate

shikimate

4-amino-4-deoxychorismate

hexulose 6-phosphate

(2S)-2-isopropylmalate

2-isopropylmaleate

(R)-mevalonate

pseudouridine 5'-phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

shikimate 3-phosphate

itaconate

hydroxylamine

(L-threonylcarbamoyl)adenylate

coproporphyrinogen III

hydrogenobyrinate

4-(β-D-ribofuranosyl)-N-succinylaminobenzene 5'-phosphate

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

3'-phosphoadenylyl-sulfate

hydrogenobyrinate a,c-diamide

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

8-amino-7-oxononanoate

pimelate

pimeloyl-CoA

prenyl diphosphate

oxaloacetate

5-enolpyruvoyl-shikimate 3-phosphate

hydrogen peroxide

methanophenazine

dihydromethanophenazine

S-adenosyl 3-(methylsulfanyl)propylamine

arsenite

quinolinate

5-aminolevulinate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

isopentenyl diphosphate

porphobilinogen

preuroporphyrinogen

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

citraconate

thiamine phosphate

thiamine diphosphate

(S)-dihydroorotate

O-ureido-L-homoserine

canavaninosuccinate

L-arginino-succinate

β-nicotinate D-ribonucleotide

β-D-ribosylnicotinate

nicotinate adenine dinucleotide

H₂

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

carbon monoxide

coenzyme B

CoB-CoM heterodisulfide

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

α-D-glucosamine 1-phosphate

prephenate

7,8-diaminopelargonate

dethiobiotin

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

3-dehydroquinate

3-dehydroshikimate

5-carboxymethyl-2-hydroxymuconate

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

3-phosphooxypyruvate

histidinal

histidinol

carbamoyl phosphate

(S)-4-amino-5-oxopentanoate

5-amino-6-(D-ribitylamino)uracil

phosphoenolpyruvate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

CO₂

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

anthranilate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

H₂O

glycerone phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

N-(5-phosphoribosyl)-anthranilate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

(2E,6E)-farnesyl diphosphate

L-homocysteine

adenosylcobalamin

cobalt-factor III

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-4

cobalt-precorrin-5A

adenosyl-cobinamide phosphate

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

cobalt-sirohydrochlorin

cobalt-precorrin-2

cob(II)yrinate c-monoamide

cobyrinate

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cobalt-precorrin-5B

cobalt-precorrin-6A

cob(II)yrinate a,c-diamide

Mg-protoporphyrin

hydrogen cyanide

N₂

uroporphyrinogen-I

uroporphyrinogen-III

protoporphyrinogen IX

protoporphyrin IX

siroheme

oxygen

sn-glycerol 1-phosphate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(R)-citramalate

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol

(S)-2-hydroxyglutarate

monodehydroascorbate radical

thiocyanate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

L-cysteate

3-sulfopyruvate

sulfoacetaldehyde

coenzyme M

(2R)-3-sulfolactate

(2R)-phospho-3-sulfolactate

sulfate

sulfite

selenate

selenide

thiosulfate

nitrate

hydrogensulfite

hydrogencarbonate

molybdate

phosphate

triphosphate

diphosphate

Mg²⁺

Co²⁺

Fe²⁺

Mo²⁺

H⁺

ammonium

agmatine

putrescine

dehydrospermidine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

methane

2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

glutaryl-CoA

2-methylacetoacetyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

succinyl-CoA

itaconyl-CoA

3'-dephospho-CoA

acetyl-CoA

crotonyl-CoA

(S)-3-hydroxybutanoyl-CoA

propanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

L-galactono-1,4-lactone

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

menaquinol-8

demethylmenaquinol-8

molybdopterin

tetrahydrosarcinapterin

5-methyl-tetrahydrosarcinapterin

coenzyme A

methyl-CoM

MoO₂-molybdopterin cofactor

oxidized coenzyme F₄₂₀-0

7,8-dihydrofolate monoglutamate

demethylated 7,8-dihydromethanopterin

7,8-dihydromethanopterin

5,10-methylene-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

L-ascorbate

nicotinate

riboflavin

pyridoxal 5'-phosphate

precorrin-3A

precorrin-1

precorrin-2

precorrin-6A

precorrin-6B

precorrin-7

precorrin-8x

precorrin-3B

precorrin-4

precorrin-5

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

molybdopterin adenine dinucleotide

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol

7,8-dihydroneopterin 2'-phosphate

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin

6-(hydroxymethyl)-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydroneopterin 2',3'-cyclic phosphate

cyclic pyranopterin phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

adenine

2'-deoxyadenosine

2'-deoxyguanosine

guanosine

inosine

xanthosine

adenosine

hypoxanthine

dAMP

dGMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

XMP

GMP

AMP

IMP

ITP

GTP

ATP

dUMP

uracil

UTP

dUDP

dUTP

dTTP

dCTP

CTP

dCMP

dCDP

UDP

CDP

orotate

dTMP

dTDP

UDP-α-D-galacturonate

UDP-α-D-glucose

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-glucosamine

cytidine

uridine

2'-deoxyuridine

2'-deoxycytidine

thymidine

thymine

UMP

CMP

salicylaldehyde

4-hydroxybenzoate

benzaldehyde

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

salicylate

4-aminobenzoate

benzoate

L-α-amino-ε-keto-pimelate

L-serine

creatine

(R)-β-lysine

L-alanine

L-leucine

L-glutamine

glycine

L-glutamate

L-lysine

L-histidine

L-arginine

L-aspartate

L-cysteine

L-tyrosine

L-threonine

L-asparagine

L-tryptophan

L-phenylalanine

L-aspartyl-4-phosphate

3-phospho-L-serine

N-acetyl-L-ornithine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

L-citrulline

L-valine

L-isoleucine

O-phospho-L-homoserine

L-homoserine

L-aspartate 4-semialdehyde

L-ornithine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

meso-diaminopimelate

L-methionine

L,L-diaminopimelate

chorismate

fumarate

succinate

(R)-malate

(S)-malate

(2R)-homocitrate

(1R,2S)-homoisocitrate

cis-homoaconitate

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

(R)-2-hydroxybutanoate

(S)-lactate

pyruvate

acetate

formate

propanoate

octanoate

apo-4'-lycopenoate

aldehydo-D-glucuronate

aldehydo-D-galacturonate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

2-oxoglutarate

2-oxobutanoate

diacetyl

glycolaldehyde

1-octanal

acetaldehyde

formaldehyde

D-glyceraldehyde

α-D-glucopyranose

β-D-glucopyranose

myo-inositol

1D-myo-inositol 2-monophosphate

1D-myo-inositol 1-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 5-monophosphate

1D-myo-inositol 4-monophosphate

1D-myo-inositol 3-monophosphate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

apo-4'-lycopenal

phytyl diphosphate

3-octaprenyl-4-hydroxybenzoate

1-(β-D ribofuranosyl)nicotinamide

maltotriose

maltotetraose

maltoheptaose

maltohexaose

maltopentaose

sucrose

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

D-ribulose-1,5-bisphosphate

sucrose 6^F-phosphate

GDP-α-D-mannose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

aldehydo-L-galactonate

L-gulonate

cyclic-AMP

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-AMP

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-ATP

β-nicotinamide D-ribonucleotide

2-iminosuccinate

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide