an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

cyclohexane-1-carbonyl-CoA

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

enolaldehyde

5,6-dimethylbenzimidazole

dialurate

(R)-1-amino-2-propanol O-2-phosphate

3-dehydroquinate

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

L-arginino-succinate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribitylamino)uracil

N⁵-carboxyaminoimidazole ribonucleotide

4-amino-2-methyl-5-pyrimidinemethanol

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(D-ribitylamino)uracil

O-ureido-L-homoserine

thiamine phosphate

thiamine diphosphate

nigerose

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

enol-phenylpyruvate

ammonia

aminoacetone

hexulose 6-phosphate

L-canavanine

urea

carbon monoxide

ethanolamine

isopentenyl diphosphate

prenyl diphosphate

γ-L-glutamyl 5-phosphate

(R)-mevalonate

(R)-5-phosphomevalonate

S-methyl-5-thio-α-D-ribose 1-phosphate

pyrazine-2-carboxylate

N¹-(5-phospho-β-D-ribosyl)glycinamide

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-phospho-β-D-ribosylamine

4-amino-4-deoxychorismate

quinolinate

β-L-arabinose 1-phosphate

nicotinate adenine dinucleotide

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

3'-phosphoadenylyl-sulfate

itaconate

deethylsimazine

N-ethylammeline

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

4-aminobutanoate

succinate semialdehyde

3-oxopropanoate

H₂

coproporphyrinogen III

(lipoyl)adenylate

3-phosphooxypyruvate

α-D-glucosamine 1-phosphate

carbamoyl phosphate

β-nicotinate D-ribonucleotide

(S)-dihydroorotate

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

S-adenosyl 3-(methylsulfanyl)propylamine

S-methyl-5'-thioadenosine

CDP-glycerol

orotidine 5'-phosphate

2-phosphoglycolate

α-D-ribose 1,5-bisphosphate

urea-1-carboxylate

hydrogen selenide

O-acetyl-L-serine

glycolate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

arsenite

oxaloacetate

glycerone phosphate

L-histidinol phosphate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

histidinal

histidinol

hydrogen peroxide

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

CO₂

(R)-4-phosphopantoate

(R)-4'-phosphopantothenate

phosphoenolpyruvate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

3-methyl-2-oxobutanoate

2-dehydropantoate

(R)-1-aminopropan-2-ol

α-ribazole

α-ribazole 5'-phosphate

H₂O

vanillin

(2E,6E)-farnesyl diphosphate

pristanate

agmatine

putrescine

dehydrospermidine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

(2Z)-2-aminobut-2-enoate

glycerophosphoglycerol

glycerophosphoserine

sn-glycero-3-phosphoethanolamine

1-oleoyl-2-palmitoyl-phosphatidylglycerol

pyrazinamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

D-glucono-1,5-lactone

glutaryl-CoA

(E)-glutaconyl-CoA

itaconyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

3'-dephospho-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

succinyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

crotonyl-CoA

phytenoyl-CoA

oleoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

octanoyl-CoA

decanoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

menaquinol-8

demethylmenaquinol-8

molybdopterin

(R)-lipoate

coenzyme A

MoO₂-molybdopterin cofactor

7,8-dihydrofolate monoglutamate

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

5,6,7,8-tetrahydrofolate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

nicotinate

riboflavin

thiamine

pyridoxal 5'-phosphate

menadione

adenine

2'-deoxyadenosine

2'-deoxyguanosine

adenosine

dAMP

dGMP

dITP

dATP

dGTP

dIDP

dADP

dGDP

IDP

GDP

ADP

XMP

IMP

GMP

AMP

ITP

GTP

ATP

dCMP

orotate

dTMP

dUMP

cytosine

dTDP

dTTP

CDP

CTP

dCDP

dCTP

dUDP

dUTP

UDP

UTP

uracil

cytidine

uridine

2'-deoxycytidine

thymidine

2'-deoxyuridine

thymine

CMP

UMP

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-glucose

UDP-α-D-galactose

UDP-β-L-arabinopyranose

UDP-N-acetyl-α-D-glucosamine

dTDP-α-D-glucose

adenosylcobalamin

cob(I)alamin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

7,8-dihydroneopterin 2'-phosphate

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin

6-(hydroxymethyl)-7,8-dihydropterin

molybdopterin adenine dinucleotide

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

cyclic pyranopterin phosphate

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydroneopterin 2',3'-cyclic phosphate

7,8-dihydropteroate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

4-hydroxybenzoate

4-aminobenzoate

menadiol

L-phenylalanine

L-tyrosine

L-histidine

D-aspartate

L-aspartyl-4-phosphate

L-2-amino-3-oxobutanoate

N-acetyl-L-ornithine

N-acetyl-L-citrulline

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

N^ω-phospho-L-arginine

3-phospho-L-serine

L-citrulline

L-canaline

L-homoserine

L-aspartate 4-semialdehyde

O-phospho-L-homoserine

S-sulfo-L-cysteine

L-homocysteine

L-ornithine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-selenocysteine

L-methionine

L-leucine

L-threonine

L-arginine

L-asparagine

L-serine

glycine

L-glutamine

L-glutamate

L-aspartate

L-cysteine

L-cystathionine

β-alanine

acetate

D-gluconate

(R)-pantoate

3-phenyl-2-oxopropanoate

pyruvate

2-oxobutanoate

glyoxylate

2-oxoglutarate

chorismate

succinate

maleate

fumarate

(S)-malate

(R)-glycerate

formate

propanoate

octanoate

decanoate

(15Z)-tetracosenoate

oleate

linoleate

α-linolenate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

phytenate

palmitate

methylglyoxal

hydroxypyruvaldehyde phosphate

glycolaldehyde

α-D-glucopyranose

β-D-glucopyranose

α-D-galactopyranose

formaldehyde

(S)-lactaldehyde

myo-inositol

1D-myo-inositol 3-monophosphate

glycerol

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

geranylgeranyl diphosphate

all-trans-octaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

3-octaprenyl-4-hydroxybenzoate

vanillylamine

N-acetyl-α-D-mannosamine

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

D-ribulose-1,5-bisphosphate

sucrose 6^F-phosphate

GDP-α-D-mannose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

6-deoxy-5-ketofructose 1-phosphate

β-D-fructofuranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

L-fuculose 1-phosphate

α-D-galactose 1-phosphate

β-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

maltotriose

maltotetraose

maltoheptaose

maltopentaose

maltohexaose

α-maltose

sucrose

1-(5-phospho-β-D-ribosyl)-AMP

5'-deoxyadenosine

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-ATP

cyclic-AMP

β-nicotinamide D-ribonucleotide

2-iminobutanoate

2-iminosuccinate

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

adenosyl-cobinamide phosphate

cob(II)yrinate a,c-diamide

cob(I)yrinate a,c-diamide

cob(I)inamide

adenosylcobinamide

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

protoporphyrinogen IX

hydrogen sulfide

oxygen

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

5,10-methenyltetrahydrofolate mono-L-glutamate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

L-cysteate

3-sulfopyruvate

tungstate

sulfate

selenate

thiosulfate

hydrogencarbonate

molybdate

chloride

phosphate

triphosphate

diphosphate

Fe³⁺

ammonium

H⁺

Zn²⁺

Co²⁺

Mn²⁺

Cd²⁺