an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

H₂O

ethanolamine

3-phosphooxypyruvate

4-phosphooxy-L-threonine

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

oxaloacetate

(2S)-2-isopropylmalate

3-methyl-2-oxobutanoate

H₂

phosphoenolpyruvate

CO₂

carbon monoxide

tartronate semialdehyde

S-adenosyl 3-(methylsulfanyl)propylamine

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

3-amino-1-hydroxyacetone 1-phosphate

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

nicotinate adenine dinucleotide

β-nicotinate D-ribonucleotide

selenophosphate

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

orotidine 5'-phosphate

2-C-methyl-D-erythritol 4-phosphate

(E)-4-coumaroyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

2,3-didehydroadipyl-CoA

butanoyl phosphate

5-enolpyruvoyl-shikimate 3-phosphate

3-dehydroshikimate

3-dehydroquinate

3-deoxy-D-arabino-heptulosonate 7-phosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

isopentenyl diphosphate

prenyl diphosphate

porphobilinogen

5-aminolevulinate

5-amino-6-(D-ribitylamino)uracil

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

4-methyl-2-oxopentanoate

enol-phenylpyruvate

L-arginino-succinate

canavaninosuccinate

O-ureido-L-homoserine

1,4-dihydroxy-2-naphthoyl-CoA

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

carbamoyl phosphate

S-methyl-5'-thioadenosine

O-D-alanyl-poly(ribitol phosphate)

poly(ribitol phosphate)

(R)-4'-phosphopantothenate

(R)-pantothenate

glycerone phosphate

DNA without lesion

acetyl phosphate

α-D-glucosamine 1-phosphate

quinolinate

4-amino-4-deoxychorismate

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

5-phospho-β-D-ribosylamine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

histidinol

histidinal

D-erythro-imidazole-glycerol-phosphate

(S)-2,3,4,5-tetrahydrodipicolinate

hydroxylamine

anthranilate

N-(5-phosphoribosyl)-anthranilate

ammonia

citrate

3'-phosphoadenylyl-sulfate

1,4-dihydroxy-2-naphthoate

(S)-2,3-dihydrodipicolinate

coproporphyrinogen III

(S)-4-amino-5-oxopentanoate

preuroporphyrinogen

α-ribazole 5'-phosphate

α-ribazole

5,6-dimethylbenzimidazole

1-deoxy-L-glycero-tetrulose 4-phosphate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

γ-L-glutamyl 5-phosphate

2-oxovalerate

3-ethylmalate

(2S)-2-isopropyl-3-oxosuccinate

4'-phosphopantetheine

2-succinylbenzoate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

succinate semialdehyde

isochorismate

2-dehydropantoate

hydrogen peroxide

2-amino-3-carboxymuconate-6-semialdehyde

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

(R)-4'-phosphopantothenoyl-L-cysteine

(R)-1-amino-2-propanol O-2-phosphate

dialurate

(S)-dihydroorotate

L-histidinol phosphate

imidazole acetol-phosphate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

N¹-(5-phospho-β-D-ribosyl)glycinamide

(S)-ureidoglycolate

5-ureidoimidazole-4-carboxylate

5-aminoimidazole-4-carboxylate

4-aminoimidazole

3,5-dihydro-4H-imidazol-4-one

xanthine

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

shikimate 3-phosphate

shikimate

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA

2-oxepin-2(3H)-ylideneacetyl-CoA

3-oxo-5,6-didehydrosuberyl-CoA

3-oxo-5,6-didehydrosuberyl-CoA semialdehyde

glutathione disulfide

hydrogen selenide

glutathioselenol

selenodiglutathione

pyruvic oxime

bisorganyltrisulfane

2-iminobutanoate

2-iminosuccinate

2-iminopropanoate

N-acetyl-L-glutaminyl-L-glutamine amide

N-acetyl-L-glutaminyl-L-glutamine

D-alanyl-D-alanine

L-homocysteine

L-α-amino-ε-keto-pimelate

L-tryptophan

L-valine

L-leucine

glycine

L-isoleucine

L-phenylalanine

L-alanine

L-methionine

L-cysteine

L-glutamine

L-glutamate

L-arginine

L-serine

L-threonine

L-aspartate

L-tyrosine

L-aspartyl-4-phosphate

L-histidine

L,L-diaminopimelate

L-lysine

L-ornithine

L-cystathionine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

L-citrulline

S-adenosyl-L-methionine

O-succinyl-L-homoserine

L-homoserine

S-adenosyl-L-homocysteine

O-phospho-L-homoserine

L-glutamate-5-semialdehyde

L-aspartate 4-semialdehyde

meso-diaminopimelate

3-phospho-L-serine

N-formimino-glycine

N-acetyl-L-glutamate

N-acetyl-L-methionine

(2S, 3S)-3-methylaspartate

D-serine

D-alanine

D-glutamate

D-aspartate

β-alanine

(S)-3-amino-2-methylpropanoate

5'-deoxyadenosine

AMP

ATP

ADP

GMP

XMP

IMP

GDP

GTP

dADP

dATP

dGDP

dGTP

1-(5-phospho-β-D-ribosyl)-ATP

dITP

dIDP

ITP

IDP

adenylo-succinate

2'-deoxyguanosine

2'-deoxyadenosine

dGMP

dAMP

1-(5-phospho-β-D-ribosyl)-AMP

hypoxanthine

ADP-α-D-glucose

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-α-D-glucose

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

adenine

guanine

purine

uracil

preQ₁

NADP⁺

NAD⁺

NADPH

NADH

dTMP

dUMP

dCMP

dUDP

dCDP

dTDP

dCTP

dUTP

dTTP

UDP

CDP

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

β-nicotinamide D-ribonucleotide

CTP

UTP

UMP

CMP

adenosine

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

5-phospho-α-D-ribose 1-diphosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

4-phospho-D-erythronate

α-D-glucopyranose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

6-deoxy-5-ketofructose 1-phosphate

D-fructose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

α-D-ribose-1-phosphate

1-deoxy-D-xylulose 5-phosphate

aldehydo-D-ribose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan dimer (mycobacteria)

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

a peptidoglycan dimer (E. faecium, tetrapeptide)

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine

a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

a peptidoglycan dimer (meso-diaminopimelate containing)

a peptidoglycan with L,D cross-links (mycobacteria)

a peptidoglycan with D,D cross-links (mycobacteria)

a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium)

β-D-fructofuranose

aldehydo-D-ribose

β-D-ribofuranose

α-D-ribofuranose

β-D-glucopyranose

α-D-glucopyranose

maltotriose

sucrose

maltopentaose

maltohexaose

maltotetraose

maltoheptaose

trans,octacis-decaprenyl phosphate

mono-trans,octa-cis-decaprenyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

di-trans,octa-cis-undecaprenyl diphosphate

all-trans-octaprenyl diphosphate

dioleoyl phosphatidate

1-oleoyl-2-lyso-glycerone phosphate

1-oleoyl-sn-glycerol 3-phosphate

1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate

methylglyoxal

acetaldehyde

caldariellaquinone

diacetyl

pyruvate

2-oxoglutarate

2-oxobutanoate

3-phenyl-2-oxopropanoate

4-aminobenzoate

orotate

allantoate

acetate

(R)-pantoate

butanoate

formate

propanoate

(R)-lactate

(R)-glycerate

(2S,3S)-2-methylcitrate

D-threo-isocitrate

chorismate

fumarate

succinate

(S)-malate

urate

6,8-dihydroxypurine

8-hydroxypurine

phenol

caldariellaquinol

demethylmenaquinol-8

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

preQ₀

tetrahydromethanopterin

7,8-dihydrofolate monoglutamate

5,6,7,8-tetrahydrofolate

tetrahydropteroyl tri-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

N⁵-methyltetrahydromethanopterin

riboflavin

FAD

FMN

FMNH₂

FADH₂

6,7-dimethyl-8-(1-D-ribityl)lumazine

dipicolinate

sirohydrochlorin

cobyrinate

cobalt-precorrin-6A

cobalt-precorrin-5B

precorrin-8x

precorrin-7

precorrin-6B

cobalt-precorrin-3

cobalt-precorrin-2

cobalt-precorrin-5A

cobalt-precorrin-4

cobalt-precorrin-6B

precorrin-2

precorrin-1

cobalt-precorrin-8

cobalt-precorrin-7

adenosylcobalamin

cob(I)alamin

nicotinate

nicotinamide

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

coenzyme A

methyl-CoM

coenzyme M

(R)-NADHX

(S)-NADHX

acetyl-CoA

succinyl-CoA

malonyl-CoA

methylacrylyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

(3S)-hydroxyadipyl-CoA

(E)-2-methylcrotonoyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

3-hydroxyisovaleryl-CoA

3'-dephospho-CoA

phenylacetyl-CoA

isobutanoyl-CoA

2-methylacetoacetyl-CoA

2-methylbutanoyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

oleoyl-CoA

3-oxoadipyl-CoA

acetoacetyl-CoA

hexadecanedioyl-CoA

propanoyl-CoA

butanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(2E)-dec-2-enoyl-CoA

(2E)-oct-2-enoyl-CoA

crotonyl-CoA

phenylacetate

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

(S)-(+)-allantoin

spermidine

putrescine

(2Z)-2-aminobut-2-enoate

2-aminoprop-2-enoate

nitrate

nitrite

selenate

hydrogencarbonate

hydrogensulfite

OH^-

trithionate

sulfite

selenide

thiosulfate

selenite

sulfate

phosphate

diphosphate

triphosphate

Co²⁺

Fe²⁺

H⁺

ammonium

trimethyl sulfonium

dimethyl sulfide

glutathione

3-sulfopyruvate

L-cysteate

sulfoacetaldehyde

S-sulfanylglutathione

(S)-3-hydroxy-isobutanoate

5,10-methenyltetrahydrofolate mono-L-glutamate

(S)-methylmalonate-semialdehyde

(R)-methylmalonate-semialdehyde

(S)-ureidoglycine

(2R)-2,3-dihydroxy-3-methylbutanoate

D-alanyl-D-lactate

3-phospho-D-glyceroyl-phosphate

2,3-diphospho-D-glycerate

2-phospho-D-glycerate

3-phospho-D-glycerate

sn-glycerol 3-phosphate

oxygen

hydrogen sulfide

protoporphyrinogen IX

uroporphyrinogen-III

protoporphyrin IX

uroporphyrinogen-I

protoheme

N₂

cobalt-sirohydrochlorin

adenosylcobyrate

adenosyl-cob(III)yrinate a,c-diamide

cob(II)yrinate a,c-diamide

cob(II)yrinate c-monoamide

adenosylcobinamide

cob(I)inamide

cob(I)yrinate a,c-diamide

adenosylcobalamin 5'-phosphate

adenosylcobinamide-GDP

adenosyl-cobinamide phosphate

cobalt-factor III

DNA with lesion

cis-1,2-dichloroethene

chloride

trichloroethene

tetrachloroethene